Complement Inhibition in Age-Related Macular Degeneration—Treat Early!
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Early therapeutic intervention in the disease course may offer the greatest benefit.
“Early therapeutic intervention in the disease course may offer the greatest benefit [279]”
From Bruch’s Membrane: A Key Consideration with Complement-Based Therapies for Age-Related Macular Degeneration (2023) · cites this paper as [279]
Cites
Liao, D. S., Grossi, F. V., Mehdi, D. E., Gerber, M. R., Brown, D. M., Heier, J. S., Wykoff, C. C., Singerman, L. J., Abraham, P., Graßmann, F., et al. (2019) · Ophthalmology · doi:10.1016/j.ophtha.2019.07.011 · Cited by 556 · see citing works
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
Weismann, D., Hartvigsen, K., Lauer, N., Bennett, K. L., Scholl, H. P. N., Issa, P. C., Cano, M., Brandstätter, H., Tsimikas, S., Skerka, C., et al. (2011) · Nature · doi:10.1038/nature10449 · Cited by 533 · see citing works
C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration
Jaffe, G. J., Westby, K., Csaky, K. G., Monés, J., Pearlman, J. A., Patel, S. S., Joondeph, B. C., Randolph, J. C., Masonson, H., & Rezaei, K. A. (2020) · Ophthalmology · doi:10.1016/j.ophtha.2020.08.027 · Cited by 484 · see citing works
Scholl, H. P. N., Fleckenstein, M., Fritsche, L. G., Schmitz-Valckenberg, S., Göbel, A. P., Adrion, C., Herold, C., Keilhauer, C. N., Mackensen, F., Mößner, A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007418 · Cited by 105 · see citing works
Self-citationMicroperimetry of Nascent Geographic Atrophy in Age-Related Macular Degeneration
Wu, Z., Ayton, L. N., Luu, C. D., et al. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-15614 · Cited by 60 · see citing works
Correction: Systemic Complement Activation in Age-Related Macular Degeneration
Scholl, H. P. N., Charbel Issa, P., Walier, M., Janzer, S., Pollok-Kopp, B., Börncke, F., Fritsche, L. G., Chong, N. V., Fimmers, R., Wienker, T., et al. (2008) · PLoS ONE · doi:10.1371/annotation/32b9bc31-ed6d-4d31-9ce0-480407017bad · Cited by 39 · see citing works
Self-citation
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Hammadi, S., Tzoumas, N., Ferrara, M., Meschede, I. P., Lo, K., Harris, C., Lako, M., & Steel, D. H. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12082870 · Cited by 44 · see citing works
- Authors
- Scholl, H. P. N.
- Affiliations
- University of Basel (CH)
- Corresponding author
- Scholl, Hendrik P. N.
- Venue
- JAMA Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 2022-03-01
- Volume
- 140
- Issue
- 3
- Pages
- 250
- ISSN
- 2168-6165 (ISSN-L)
- OpenAlex
- W4210681215
- Cited by
- 6
- References
- 6
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2022: 1
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Life Sciences › Immunology and Microbiology › Immunology › Complement system in diseases
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Keywords
- age-related macular degeneration, complement inhibition, early treatment, complement system
- MeSH terms
- Animals, Atrophy, Female, Horses, Humans, Macular Degeneration, Peptides, Cyclic, Retinal Pigment Epithelium
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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