Perinatal Depression Screening Among Sexual Minority Women
Open accessAbstract
Importance: A substantial number of births in the US are to sexual minority women (17% based on a nationally representative survey), yet there is little research on perinatal depression screening rates or symptom endorsement among sexual minority women (including women who identify as lesbian, bisexual, queer, pansexual, asexual, demisexual, and kinky as well as other-identified women who have sex with women). High rates of risk factors for perinatal depression (eg, intimate partner violence and history of mental illness) among sexual minority individuals magnify this gap in the literature. Objective: To describe the prevalence of female-identified sexual minority people giving birth in an academic medical center and compare perinatal depression screening rates and scores among sexual minority women and heterosexual cisgender women. Design, Setting, and Participants: This retrospective cohort study used deidentified medical record review of 18 243 female-identified individuals who gave birth at an academic medical center in Chicago, Illinois, between January 1 and December 31, 2019. Data were analyzed from April 5, 2021, to August 1, 2022. Main Outcomes and Measures: Proportion of women identified as having sexual minority status in the medical record, rates of standard care administration of the 9-item Patient Health Questionnaire between sexual minority women and heterosexual women, and depression screening scores and rates of positive depression screening results for sexual minority and heterosexual women. Results: Among 18 243 women (mean [SD] age, 33.8 [5.1] years; 10 453 [57.3%] of non-Hispanic White race and ethnicity), only 280 (1.5%; 95% CI, 1.3%-1.7%) were identified as having sexual minority status in the medical record. Significantly more sexual minority women vs heterosexual women attended at least 1 prenatal care visit (56 [20.0%] vs 2459 [13.7%]; P = .002) and at least 1 postpartum care visit (52 [18.6%] vs 2304 [12.8%]; P = .004). Sexual minority women were more likely to be screened for depression during postpartum care (odds ratio, 1.77; 95% CI, 1.22-2.52; P = .002) and more likely to screen positive for depression during the postpartum period (odds ratio, 2.38; 95% CI, 0.99-5.02; P = .03) than heterosexual women. Conclusions and Relevance: In this cohort study, sexual minority women identified in the medical record were highly engaged in obstetric care yet at high risk of postpartum depression. In addition, their sexual orientation was largely undocumented in medical records. These results highlight the need for investigations that include strategies for measuring sexual orientation because medical record review is unlikely to reliably capture these sexual identities during the perinatal period.
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Sexual and gender minority parents are at greater risk for internalizing problems and may experience stigma and discrimination in obstetrical settings.
“Exploring patterns and predictors of internalizing problems among a more diverse group of parents is particularly important given that sexual and gender minority parents are at greater risk for internalizing problems [108] and may experience stigma and discrimination in obstetrical settings [109].”
From Trajectories of Maternal and Paternal Internalizing Symptoms from Pregnancy to 2 Years Postpartum: Identifying Modifiable Risk and Protective Factors (2024) · cites this paper as [108]
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Lu, J. A., Soltani, S., Austin, S. B., Rehkopf, D. H., Lunn, M. R., & Langston, M. E. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.56264 · Cited by 44 · see citing works
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- Authors
- Lapping-Carr, L., Dennard, A., Wisner, K. L., & Tandon, S. D.
- Affiliations
- Northwestern University (US)
- Corresponding author
- Lapping-Carr, Leiszle
- Venue
- JAMA Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2023-11-01
- Volume
- 80
- Issue
- 11
- Pages
- 1142
- ISSN
- 2168-622X (ISSN-L)
- PMC
- PMC10398540
- OpenAlex
- W4385476017
- Cited by
- 14
- References
- 46
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 8
- FWCI
- 3.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Keywords
- perinatal depression, sexual minority women, depression screening, Patient Health Questionnaire, postpartum depression, prenatal care, postpartum care, intimate partner violence, maternal mental health, LGBTQ health disparities, lesbians, bisexual women, queer women
- MeSH terms
- Sexual and Gender Minorities, Adult, Depression, Female, Humans, Male, Pregnancy, Retrospective Studies, Sexual Behavior, Cohort Studies, Homosexuality, Female
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