The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Overview of Animal Models of Obesity
Open accessAbstract
The focus of this overview is on the animal models of obesity most commonly utilized in research. The models include monogenic models in the leptin pathway, polygenic diet‐dependent models, and, in particular for their historical perspective, surgical and chemical models of obesity. However, there are far too many models to consider all of them comprehensively, especially those caused by selective molecular genetic approaches modifying one or more genes in specific populations of cells. Further, the generation and use of inducible transgenic animals (induced knock‐out or knock‐in) is not covered, even though they often carry significant advantages compared to traditional transgenic animals, e.g., influences of the genetic modification during the development of the animals can be minimized. The number of these animal models is simply too large to be covered in this unit. Curr. Protoc. Pharmacol. 58:5.61.1‐5.61.18. © 2012 by John Wiley & Sons, Inc.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., & Burn, P. (1995) · Science · doi:10.1126/science.7624778 · Cited by 3,243
Epigenetic inheritance at the agouti locus in the mouse
Morgan, H. D., Sutherland, H. G. E., Martin, D. I. K., & Whitelaw, E. (1999) · Nature Genetics · doi:10.1038/15490 · Cited by 1,476
Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis
Bray, G. A., & York, D. A. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.3.719 · Cited by 1,132
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
Bates, S. H., Stearns, W. H., Dundon, T. A., Schubert, M., Tso, A. W. K., Wang, Y., Banks, A. S., Lavery, H. J., Haq, A. K., Maratos-Flier, E., et al. (2003) · Nature · doi:10.1038/nature01388 · Cited by 1,010 · cited 1×
“Analogous to the ob gene mutation, the mutation of the leptin receptor gene is also found in some human families; however, the mutation is very rare. s/s mouse The s/s mouse is a more specific, genetically engineered animal model of leptin receptor deficiency (Bates et al., 2003, 2005).”
BackgroundBenoit, S. C., Kemp, C. J., Elias, C. F., Abplanalp, W., Herman, J. P., Migrenne, S., Lefevre, A.-L., Cruciani-Guglielmacci, C., Magnan, C., Yu, F., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36714 · Cited by 351
Bates, S. H., Kulkarni, R. N., Seifert, M., & Myers, M. G. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.02.001 · Cited by 173
Cited by
Is Weight Loss Harmful for Skeletal Health in Obese Older Adults?
Papageorgiou, M., Kerschan-Schindl, K., Sathyapalan, T., & Pietschmann, P. (2020) · Gerontology · doi:10.1159/000500779 · Cited by 45
Transgenerational effects of obesogenic diets in rodents: A meta‐analysis
Anwer, H., Morris, M. J., Noble, D. W. A., Nakagawa, S., & Lagisz, M. (2022) · Obesity Reviews · doi:10.1111/obr.13342 · Cited by 14
Metadata
- Authors
- Lutz, T. A., & Woods, S. C.
- Venue
- Current Protocols in Pharmacology
- Publisher
- Wiley
- Published
- 2012-09
- Volume
- 58
- Issue
- 1
- Pages
- Unit5.61-Unit5.61
- ISSN
- 1934-8282 (ISSN-L)
- 1934-8290
- OpenAlex
- W1542645650
- Cited by
- 375
- References
- 7
- FWCI
- 4.56
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Overview of Animal Models of Obesity. https://app.cochat.ai/papers/10.1002/0471141755.ph0561s58
- The paper
- Lutz, T. A., & Woods, S. C. (2012). Overview of Animal Models of Obesity. Current Protocols in Pharmacology. https://doi.org/10.1002/0471141755.ph0561s58
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
