Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis

Effects of the <i>obese</i> Gene Product on Body Weight Regulation in <i>ob</i> / <i>ob</i> Mice

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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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Identification and expression cloning of a leptin receptor, OB-R.

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Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

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Leptin

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A leptin missense mutation associated with hypogonadism and morbid obesity

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Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

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Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

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Leptin Regulation of Neuroendocrine Systems

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

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Human Leptin Deficiency Caused by a Missense Mutation: Multiple Endocrine Defects, Decreased Sympathetic Tone, and Immune System Dysfunction Indicate New Targets for Leptin Action, Greater Central than Peripheral Resistance to the Effects of Leptin, and Spontaneous Correction of Leptin-Mediated Defects

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Metabolic fuels and reproduction in female mammals

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Leptin in Human Physiology and Pathophysiology

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Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

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Leptin is a potent stimulator of bone growth in ob/ob mice

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Visceral Obesity: A “Civilization Syndrome”

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Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

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Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

Gao, Q., Wolfgang, M. J., Neschen, S., Morino, K., Horvath, T. L., Shulman, G. I., & Fu, X.-Y. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0303992101 · Cited by 385 · see citing works

The carbohydrate-insulin model: A physiological perspective on the obesity pandemic

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Obesity, A Disorder Of Nutrient Partitioning: The MONA LISA Hypothesis

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Glucose-Induced Intracellular Ion Changes in Sugar-Sensitive Hypothalamic Neurons

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Thermic effect of glucose in man. Obligatory and facultative thermogenesis.

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Hypertension in Obese Zucker Rats: Role of Angiotensin II and Adrenergic Activity

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Involvement of Sex, Strain and Age Factors in High Fat Diet-Induced Obesity in C57BL/6J and BALB/cA Mice

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Insulin: its relationship to the central nervous system and to the control of food intake and body weight

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Cardiac Myocyte Apoptosis Is Associated With Increased DNA Damage and Decreased Survival in Murine Models of Obesity

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Influence of beta-adrenergic blockade on glucose-induced thermogenesis in man.

Acheson, K., Jéquier, E., & Wahren, J. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111070 · Cited by 171 · see citing works

Opposite effects of leptin on bone metabolism: a dose-dependent balance related to energy intake and insulin-like growth factor–I pathway

Martin, A., David, V., Malaval, L., Lafage-Proust, M.-H., Vico, L., & Thomas, T. (2007) · Endocrinology · doi:10.1210/en.2006-1541 · Cited by 111 · see citing works

Obesity and food intake in children: Evidence for a role of metabolic and/or behavioral daily rhythms

Bellisle, F., Rolland-Cachera, M.-F., Deheeger, M., & Guilloud-Bataille, M. (1988) · Appetite · doi:10.1016/s0195-6663(88)80010-2 · Cited by 83 · see citing works

The development of obesity in animals: The role of dietary factors

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IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis

Gao, Y., Liu, Y., Yang, M., Guo, X., Zhang, M., Li, H., Li, J., & Zhao, J. (2016) · Oncotarget · doi:10.18632/oncotarget.9259 · Cited by 79 · see citing works

Leptin substitution results in the induction of menstrual cycles in an adolescent with leptin deficiency and hypogonadotropic hypogonadism

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Effect of impaired glucose tolerance and type II diabetes on resting metabolic rate and thermic response to a glucose meal in obese women

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Insulin binding in the hypothalamus of lean and genetically obese Zucker rats

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Glucose-dependent alterations of intracellular free calcium by glucagon-like peptide-1(7-36amide) in individual mouse β-cells

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The temporal role of leptin within fracture healing and the effect of local application of recombinant leptin on fracture healing

Khan, S. N., DuRaine, G., Virk, S. S., Fung, J., Rowland, D. J., Reddi, A. H., & Lee, M. A. (2013) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0b013e3182847968 · Cited by 28 · see citing works

Low 24-hour core body temperature as a thrifty metabolic trait driving catch-up fat during weight regain after caloric restriction

Calonne, J., Arsenijevic, D., Scerri, I., Miles-Chan, J. L., Montani, J.-P., & Dulloo, A. G. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00092.2019 · Cited by 15 · see citing works

Exogenous Glucocorticoids and a High-Fat Diet Cause Severe Hyperglycemia and Hyperinsulinemia and Limit Islet Glucose Responsiveness in Young Male Sprague-Dawley Rats

Beaudry, J. L., D'souza, A. M., Teich, T., Tsushima, R. G., & Riddell, M. C. (2013) · Endocrinology · doi:10.1210/en.2012-2114 · Cited by 44 · see citing works

The Effect of Fasting on Tissue Cyclic cAMP and Plasma Glucagon in the Obese Hyperglycemic Mouse

VINE, R. L. L., Voyles, N. R., Perrino, P. V., & Recant, L. (1975) · Endocrinology · doi:10.1210/endo-97-3-615 · Cited by 38 · see citing works

Modulation of Adipoinsular Axis in Prediabetic Zucker Diabetic Fatty Rats by Diazoxide

Alemzadeh, R., & Tushaus, K. (2004) · Endocrinology · doi:10.1210/en.2003-1523 · Cited by 38 · see citing works

The Paraventricular Nucleus of the Hypothalamus Has a Major Role in Thyroid Hormone Feedback Regulation of Thyrotropin Synthesis and Secretion

Taylor, T., Wondisford, F. E., Blaine, T. A., & Weintraub, B. D. (1990) · Endocrinology · doi:10.1210/endo-126-1-317 · Cited by 54 · see citing works

Growth hormone binding protein in the rat: effects of gonadal steroids

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