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Next Generation Sequence Assembly with AMOS

Open access
Treangen, Todd J., Sommer, Dan D., Angly, Florent E., Koren, Sergey, Pop, Mihai·2011·Current Protocols in Bioinformatics

Abstract

A Modular Open‐Source Assembler (AMOS) was designed to offer a modular approach to genome assembly. AMOS includes a wide range of tools for assembly, including the lightweight de novo assemblers Minimus and Minimo, and Bambus 2, a robust scaffolder able to handle metagenomic and polymorphic data. This protocol describes how to configure and use AMOS for the assembly of Next Generation sequence data. Additionally, we provide three tutorial examples that include bacterial, viral, and metagenomic datasets with specific tips for improving assembly quality.Curr. Protoc. Bioinform. 33:11.8.1‐11.8.18. © 2011 by John Wiley & Sons, Inc.

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Metadata

Authors
Treangen, T. J., Sommer, D. D., Angly, F. E., Koren, S., & Pop, M.
Venue
Current Protocols in Bioinformatics
Publisher
Wiley
Published
2011-03
Volume
33
Issue
1
Pages
Unit 11.8-Unit 11.8
ISSN
  • 1934-3396 (ISSN-L)
  • 1934-340X
OpenAlex
W1550594300
Cited by
212
References
2
FWCI
4.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Next Generation Sequence Assembly with AMOS. https://app.cochat.ai/papers/10.1002/0471250953.bi1108s33
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Treangen, T. J., Sommer, D. D., Angly, F. E., Koren, S., & Pop, M. (2011). Next Generation Sequence Assembly with AMOS. Current Protocols in Bioinformatics. https://doi.org/10.1002/0471250953.bi1108s33

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