Nasal decongestants for the common cold
Abstract
Background The common cold is a major and recurrent cause of morbidity, on average affecting children and adults two or more times each year. Nasal congestion is its commonest symptom and many therapies are marketed for its relief. There is no meta-analysis of controlled clinical trials on the effects of nasal decongestants in the common cold. Objectives To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use. Search strategy In this updated review in 2006, the following databases were searched: the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 3, 2006); MEDLINE (January 1996 to September 2006); OLDMEDLINE (1951 to 1965); EMBASE (1980 to Week 36, 2006). We contacted known principal investigators and pharmaceutical companies. Selection criteria Randomised, placebo controlled trials of single-active oral and topical nasal decongestants in adults and children suffering from common cold. Data collection and analysis Two review authors (DT and GJL) independently extracted data. All outcomes variables were continuous. Subjective outcomes were normalised to a common scale and a weighted mean difference (WMD) was calculated. A standardised mean difference (SMD) was calculated for the objective outcomes. Main results Seven studies in adults, but none in children, fitted all inclusion criteria. There was…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
One systematic review showed that a single intranasal dose significantly improved acute nasal congestion and reduced nasal airway resistance in adults with common cold.
“One systematic review showed that a single intranasal dose significantly improved acute nasal congestion and reduced nasal airway resistance in adults with common cold [125].”
From Position Paper on Nasal Obstruction: Evaluation and Treatment (2018) · cites this paper as [125]
Cites
Moher, D., Jadad, A. R., Nichol, G., Penman, M., Tugwell, P., & Walsh, S. (1995) · Controlled Clinical Trials · doi:10.1016/0197-2456(94)00031-w · Cited by 1,308 · see citing works
Bye, C. E., Cooper, J., Empey, D. W., Fowle, A. S., Hughes, D. T., Letley, E., & O'Grady, J. (1980) · BMJ · doi:10.1136/bmj.281.6234.189 · Cited by 46 · see citing works
Sperber, S. J. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.10.979 · Cited by 28 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Allergic Rhinitis and Its Impact on Asthma
Bousquet, J., van Cauwenberge, P., & Khaltaev, N. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.118891 · Cited by 3,588 · see citing works
Prevention and treatment of the common cold: making sense of the evidence
Allan, G. M., & Arroll, B. (2014) · Canadian Medical Association Journal · doi:10.1503/cmaj.121442 · Cited by 207 · see citing works
“with a single dose and 4% with recurrent doses, but clinical relevance is uncertain.(56) Although”
BackgroundOral antihistamine-decongestant-analgesic combinations for the common cold
Sutter, A. I. D., van Driel, M., Kumar, A. A., Lesslar, O., & Skrt, A. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004976.pub3 · Cited by 90 · see citing works
Lai, K., Shen, H., Zhou, X., Qiu, Z., Shaoxi, C., Huang, K., Wang, Q., Wang, C., Lin, J., Hao, C., et al. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.09.153 · Cited by 133 · see citing works
“Combined treatment with decongestants and firstgeneration antihistamines (brompheniramine maleate and pseudoephedrine) can significantly improve cough, sneezing, and nasal discharge in adult and adolescent patients (114-116) (2A).”
BackgroundFalagas, M., Giannopoulou, K., Vardakas, K., Dimopoulos, G., & Karageorgopoulos, D. (2008) · Lancet. Infectious Diseases (Print) · doi:10.1016/s1473-3099(08)70202-0 · Cited by 109 · see citing works
Nasal decongestants in monotherapy for the common cold
Deckx, L., De Sutter, A. I., Guo, L., Mir, N. A., & van Driel, M. L. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009612.pub2 · Cited by 107 · see citing works
Smith, T. J., Radler, D. R., Denmark, R., Haley, T. F., & Touger-Decker, R. E. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512004138 · Cited by 86 · see citing works
“Further, OTC drugs may have unwanted side effects, such as drowsiness((11)), xerostomia (dry mouth)((11)), nervousness((11)), irritability((11)), difficulty sleeping((11,12)) and elevated blood pressure((12)).”
BackgroundAdverse drug reactions in childhood: a review of prospective studies and safety alerts
Clavenna, A., & Bonati, M. (2009) · Archives of Disease in Childhood · doi:10.1136/adc.2008.154377 · Cited by 90 · see citing works
Position Paper on Nasal Obstruction: Evaluation and Treatment
SEAIC Rhinoconjunctivitis Committee & SEORL Rhinology, A., Valero, A., Navarro, A., del Cuvillo, A., Alobid, I., Benito, Jr., Colás, C., de los Santos, G., Fernández Liesa, R., García-Lliberós, A., et al. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0232 · Cited by 76 · see citing works
Eccles, R. (2007) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2006.02833.x · Cited by 73 · see citing works
Fazekas, T., Eickhoff, P., Pruckner, N., Vollnhofer, G., Fischmeister, G., Diakos, C., Rauch, M., Verdianz, M., Zoubek, A., Gadner, H., et al. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-147 · Cited by 71 · see citing works
“Due to insufficient data on the application of nasal decongestants for common cold in children, their use is not recommended in patients below 12 years of age [20].”
BackgroundBakhriansyah, H. M., Farmakologi, B., Unlam, F. K., Obstruktif, P. P., Ppom, M., & Terapi, P. (2024) · doi:10.1007/springerreference_31994 · Cited by 67
Nasal decongestants in the treatment of chronic nasal obstruction: efficacy and safety of use
Passàli, D., Salerni, L., Passali, G., Passàli, F., & Bellussi, L. (2006) · Expert Opinion on Drug Safety · doi:10.1517/14740338.5.6.783 · Cited by 67
“(2006) 5(6) 785 nasal decongestants, through the activation of α-adrenergic receptors, which increase noradrenalin release by the adrenergic terminations, lead to rapid relief of obstructive symptoms thanks to their vasoconstrictive action on capacitance blood vessels, particularly abundant in the nasal mucosa [4], an…”
BackgroundHunter, J., Arentz, S., Goldenberg, J., Yang, G.-Y., Beardsley, J., Myers, S., Mertz, D., & Leeder, S. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-047474 · Cited by 57 · see citing works
Acetaminophen (paracetamol) for the common cold in adults
Li, S., Yue, J., Dong, B. R., Yang, M. J., Lin, X., & Wu, T. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008800.pub2 · Cited by 50 · see citing works
Leitlinie „Rhinosinusitis“ – Langfassung
Stuck, B., Beule, A. G., Jobst, D., Klimek, L., Laudien, M., Lell, M., Vogl, T. J., & Popert, U. (2017) · HNO · doi:10.1007/s00106-017-0401-5 · Cited by 75 · see citing works
Lissiman, E., Bhasale, A. L., & Cohen, M. M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006206.pub4 · Cited by 143 · see citing works
The pathophysiology, clinical impact, and management of nasal congestion in allergic rhinitis.
Nathan, R. (2008) · Clinical Therapeutics · doi:10.1016/j.clinthera.2008.04.011 · Cited by 49 · see citing works
The diagnosis and treatment of acute cough in adults.
Holzinger, F., Beck, S., Dini, L., Stöter, C., & Heintze, C. (2014) · Deutsches Ärzteblatt International · doi:10.3238/arztebl.2014.0356 · Cited by 48 · see citing works
Restricting cough and cold medicines in children
Isbister, G., Prior, F., & Kilham, H. (2012) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2010.01780.x · Cited by 41 · see citing works
Examining the evidence for the use of vitamin C in the prophylaxis and treatment of the common cold
Heimer, K., Hart, A., Martin, L., & Rubio-Wallace, S. (2009) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.2009.00409.x · Cited by 39 · see citing works
“The common cold presents amajor nuisance to activities of daily living and is one of the most recurrent and common causes of morbidity (Taverner & Latte, 2007).”
BackgroundKollar, C., Schneider, H., Waksman, J., & Krusinska, E. (2007) · Clinical Therapeutics · doi:10.1016/j.clinthera.2007.05.021 · Cited by 39 · see citing works
Picon, P. D., Costa, M. B., Picon, R. V., Fendt, L. C. C., Suksteris, M. L., Saccilotto, I. C., Dornelles, A. D., & Schmidt, L. F. C. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-556 · Cited by 36 · see citing works
Pharmacology of cough and cold medicines.
Woo, T. (2008) · Journal of Pediatric Health Care · doi:10.1016/j.pedhc.2007.12.007 · Cited by 34
Upper Respiratory Tract Infections (Including Otitis Media)
Morris, P. S. (2009) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2008.10.009 · Cited by 41 · see citing works
“Of these interventions, only decongestants have been proven to be effective, but their beneficial effect is small.(26) Decongestants have not”
BackgroundSafety and efficacy of over- the-counter cough and cold medicines for use in children
Vassilev, Z., Kabadi, S. M., & Villa, R. (2010) · Expert Opinion on Drug Safety · doi:10.1517/14740330903496410 · Cited by 30
“The efficacy of decongestant use remains unproven in children [26].”
BackgroundStuck, B., Bachert, C., Federspil, P., Hosemann, W., Klimek, L., Mösges, R., Pfaar, O., Rudack, C., Sitter, H., Wagenmann, M., et al. (2007) · HNO (Berlin. Print) · doi:10.1007/s00106-007-1589-6 · Cited by 25 · see citing works
Mösges, R., Shah-Hosseini, K., Hucke, H., & Joisten, M. (2017) · Advances in Therapy · doi:10.1007/s12325-017-0581-0 · Cited by 23 · see citing works
“This situation leads to a reduction in hypersecretion and reduced nasal blockage [5, 6].”
BackgroundKung, K., Wong, C., Wong, S., Lam, A., Chan, C., Griffiths, S., & Butler, C. (2014) · BMC Family Practice · doi:10.1186/1471-2296-15-95 · Cited by 23 · see citing works
“Evidence shows that symptomatic medications including antibiotics are of marginal or no benefit [7-13].”
BackgroundSumaila, A.-N., & Tabong, P. (2018) · BMC Research Notes · doi:10.1186/s13104-018-3542-z · Cited by 22 · see citing works
Upper Respiratory Tract Infections in Athletes
Page, C. L., & Diehl, J. J. (2007) · Clinics in Sports Medicine · doi:10.1016/j.csm.2007.04.001 · Cited by 22 · see citing works
“Sinusitis is one of the most common illnesses diagnosed in the United States, affecting about 16% of the adult population annually [16].”
BackgroundInfluentialTopical treatment of rhinosinusitis
Fiocchi, A., Sarratud, T., Bouygue, G. R., Ghiglioni, D., Bernardo, L., & Terracciano, L. (2007) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2007.00637.x · Cited by 19
“However, a systematic review of randomized, placebo-controlled trials found in favor of a modest effect of oral and nasal decongestants in the relief of common cold symptoms (26).”
BackgroundSymptomatic treatment of upper respiratory tract symptoms in children
Green, R. J. (2006) · doi:10.1080/20786204.2006.10873374 · Cited by 18
“However, all other therapies have never been proven to work.(8) These include antihistamines, oral decongestants and antitussives and especially combination preparations.”
BackgroundViral Upper Respiratory Infection
Barrett, B. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35868-2.00018-9 · Cited by 22 · see citing works
Hersberger, K., Botomino, A., Sarkar, R., Tschudi, P., Bucher, H. C., & Briel, M. (2009) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/j.1365-2710.2009.01049.x · Cited by 16 · see citing works
Rise and fall of decongestants in treating nasal congestion related diseases
Wang, J., Mao, Z.-F., & Cheng, L. (2024) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2024.2411009 · Cited by 14 · see citing works
“A single nasal decongestant effectively reduces the overall subjective symptoms of nasal congestion by 13% within 2 h, suggesting that nasal decongestants provide excellent clinical benefits in patients with common cold [68].”
Thielmann, A., Gerasimovska-Kitanovska, B., Buczkowski, K., Koskela, T., Mevsim, V., Czachowski, S., Petrazzuoli, F., Petek-Šter, M., Lingner, H., Hoffman, R., et al. (2016) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2016/6949202 · Cited by 14 · see citing works
“(4) “Evidence-based self-care”: based on 14 Cochrane reviews [15–17, 20–30] and one other review [31], items were grouped according to their evidence of effectiveness for the treatment of common colds in adults.”
BackgroundAcute coronary syndrome after nasal spray of oxymetazoline.
Montastruc, F., Montastruc, G., Taudou, M., Olivier-Abbal, P., Montastruc, J., & Bondon-Guitton, E. (2014) · Chest · doi:10.1378/chest.14-1873 · Cited by 12
Mostov, P. D. (2007) · Primary Care · doi:10.1016/j.pop.2006.09.009 · Cited by 12 · see citing works
“Use of oral and topical nasal decongestants provides benefit for shortterm use in adults; there is no evidence supporting their use in children [18].”
BackgroundAlharthi, A., Alharthi, S. A., Altowairqi, A., Alswat, S. H., & Alnofaie, M. F. (2022) · Cureus · doi:10.7759/cureus.31892 · Cited by 10 · see citing works
Evaluation of the prescriptions written for upper respiratory tract infections
Ozdemir, S., Ozturk, T., Metiner, Y., Ak, R., & Ocal, O. (2015) · İstanbul Kuzey Klinikleri · doi:10.14744/nci.2015.69885 · Cited by 10 · see citing works
“, while usefulness of antihistamines could not be demonstrated [11, 16].”
BackgroundComplementary and Integrative Treatments
Weiss, J. R., Tessema, B., & Brown, S. M. (2013) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2012.12.007 · Cited by 9 · see citing works
Huang, S., Constant, S., Servi, B. D., Meloni, M., Culig, J., Bertini, M., & Saaid, A. (2019) · Medical devices · doi:10.2147/mder.s209644 · Cited by 9
“In addition, commonly used medications in adults including vasoconstrictors such as pseudoephedrine and phenylephrine or bronchodilators such as ipratropium, have modest effects on symptom alleviation and duration.(7) Furthermore, nasally administered vasoconstrictors such as oxymetazoline, pseudoephedrine, phenylephr…”
BackgroundPediatric allergy medications: review of currently available formulations
Scadding, G. (2009) · Current Medical Research and Opinion · doi:10.1185/03007990903116875 · Cited by 9
Upper Respiratory Infections in Adults
Kim, S. (2010) · Journal of Korean Medical Association · doi:10.5124/jkma.2010.53.1.10 · Cited by 11 · see citing works
Septimus, E., Albrecht, H., Solomon, G., Shea, T., & Guenin, E. (2017) · Current Therapeutic Research · doi:10.1016/j.curtheres.2017.04.004 · Cited by 7 · see citing works
Evidence and evidence gaps in therapies of nasal obstruction and rhinosinusitis
Rotter, N. (2016) · GMS current topics in otorhinolaryngology, head and neck surgery · doi:10.3205/cto000133 · Cited by 7 · see citing works
“with threemeta-analyses [37], [38], [39] and one systematic review [40] found.”
BackgroundInfections of the Upper Respiratory Tract
Asher, M. I., & Grant, C. C. (2008) · Elsevier eBooks · doi:10.1016/b978-032304048-8.50036-0 · Cited by 40 · see citing works
Choi, I.-K., Lee, H.-K., Ji, Y.-J., Hwang, I.-H., & Kim, S. Y. (2013) · Korean Journal of Family Medicine · doi:10.4082/kjfm.2013.34.4.241 · Cited by 6 · see citing works
Complementary and Integrative Treatments
Garbo, G., Tessema, B., & Brown, S. M. (2013) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2012.12.005 · Cited by 3 · see citing works
Evidence-Based Pediatric Infectious Diseases
Isaacs, D. (2007) · doi:10.1002/9780470692172 · Cited by 6
Geppe, N. A., Oserskaya, I. V., & Kolosova, N. G. (2019) · Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) · doi:10.21508/1027-4065-2019-64-5-14-20 · Cited by 5 · see citing works
Nasal patches containing naphazoline for management of nasal impairments
Laffleur, F., Strasdat, B., Mahmood, A., Reichenberger, T., Gräber, M., & Netsomboon, K. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.02.012 · Cited by 5 · see citing works
Weltermann, B., Gerasimovska-Kitanovska, B., Thielmann, A., Chambe, J., Lingner, H., Pirrotta, E., Buczkowski, K., Tekiner, S., Czachowski, S., Edirne, T., et al. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/272189 · Cited by 6 · see citing works
“The evidence for common cold treatments is poor with only few medications proven effective in relieving symptoms or in reducing the duration of the disease, for example, nonsteroidal anti-inflammatory drug [9], oral antihistaminedecongestant-analgesic combinations [10], nasal decongestants [11], and zinc (lozenges or…”
Responsible Prescribing for Upper Respiratory Tract Infections
Turnidge, J. (2012) · Drugs · doi:10.2165/00003495-200161140-00004 · Cited by 5
“Single doses have been shown to be quite effective in short term relief of symptoms but repeated use over days shows little extra benefit.[20] Nasal decongestants are not without their problems, and alternatives such as saline nasal sprays are recommended by some to prevent the rebound congestion associated with decon…”
BackgroundPeynegre, R., Dessanges, J. F., Bruhwyler, J., & Concas, V. (2005) · Annales d Otolaryngologie et de Chirurgie Cervico-Faciale · doi:10.1016/s0003-438x(05)82356-4 · Cited by 3 · see citing works
Evidenz und Evidenzlücken bei der Behandlung der behinderten Nasenatmung und der Rhinosinusitis
Rotter, N. (2016) · Laryngo-Rhino-Otologie · doi:10.1055/s-0041-109059 · Cited by 3
Therapeutic management of allergic diseases
Watelet, J., Gillard, M. R., Benedetti, M. S., Lelièvre, B., & Diquet, B. (2009) · Drug Metabolism Reviews · doi:10.1080/10837450902891204 · Cited by 4 · see citing works
“In a recent Cochrane systematic review (Taverner and Latte, 2007), decongestants induce a small, but statistically significant, 6% decrease in subjective symptoms after a single dose of decongestant, compared with placebo.”
BackgroundNasir, F., Itrat, M., & Kunnavil, R. (2024) · Advances in Integrative Medicine · doi:10.1016/j.aimed.2024.10.005 · Cited by 2
The use of decongestants in children in otorhinolaryngological practice
Egorova, O. (2021) · Pediatrics. Consilium Medicum · doi:10.26442/26586630.2021.2.200906 · Cited by 2
Nasal decongestants for the common cold
Ta’i, S., Ferguson, K. A., Singh, H. K., Sharma, A. N., Kumar, S., van Driel, M., & Sutter, A. I. M. D. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009612 · Cited by 3 · see citing works
Diagnosis and recommended treatment of common URTIs
Virgincar, N., & Spencer, R. (2008) · Prescriber · doi:10.1002/psb.244 · Cited by 2 · see citing works
[Systemic and local antibiotic therapy for acute sinusitis].
Nosulya, E. V., Kunelskaya, N., & Kim, I. A. (2020) · Vestnik otorinolaringologii · doi:10.17116/otorino20208505140 · Cited by 2
Infections of the upper respiratory tract
Francis, N., & Butler, C. (2010) · Elsevier eBooks · doi:10.1016/b978-0-7020-4064-1.00044-0 · Cited by 2 · see citing works
Intoxicación accidental por descongestionante tópico nasal
Campos, S. R., Santervás, Y. F., Jordana, E., & Cubells, C. (2006) · doi:10.1016/s1695-4033(06)70023-6 · Cited by 2
Svistushkin, V., Morozova, S. V., & Keda, L. (2021) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2021-6-36-42 · Cited by 1 · see citing works
The efficacy of silver proteinate in the treatment of acute nasopharyngitis
Sobolev, V. P., Свистушкин, В. М., Leyzerman, M. G., Magomedov, K. R., Bidanova, D. B., & Budagova, G. N. (2020) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2020-16-43-49 · Cited by 4 · see citing works
“Промывание полости носа приводит к снижению микробной контаминации, микроэлементный состав раствора, которым проводится ирригация (чаще это морская вода), улучшает мукоцилиарный клиренс, стимулирует барьерную функцию слизистой оболочки [26, 27].”
Применение местных деконгестантов в детской практике
Бараташвили, А. Д., & Карпова, Е. П. (2017) · doi:10.21518/2079-701x-2017-9-44-47 · Cited by 1
Leitliniengerechte Therapie von Schnupfen und Sinusitis
Dippold, N., & Klimek, L. (2017) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-017-9158-8 · Cited by 1 · see citing works
Ganzheitliche Therapieoptionen bei akuten Atemwegsinfekten
Croessmann, M., & Rose, M. A. (2016) · Der Pneumologe · doi:10.1007/s10405-016-0052-3 · Cited by 1 · see citing works
“Die Evidenz der zugrunde liegenden Studien ist jedoch von niedriger bis sehr niedrigerQualität [55].”
BackgroundDrug therapy for the common cold
Kim, S. (2015) · Journal of Korean Medical Association · doi:10.5124/jkma.2015.58.2.147 · Cited by 1 · see citing works
“성인에서 충혈완화제는 경구, 국소 약제 모두 기침 증상호전에 위약에 비해 효과적이었다[25].”
KAPITEL 28 – Entzündliche Erkrankungen der Nase und der Nasennebenhöhlen
Klimek, L. (2009) · Elsevier eBooks · doi:10.1016/b978-3-437-24660-9.10028-4 · Cited by 1 · see citing works
Chang, A. B. (2009) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2008.11.001 · Cited by 1 · see citing works
“Some of the skeletal abnormalities associated with this syndrome include increased height and arm span, scoliosis, thoracic lordosis, and disorders of the anterior chest, including pectus deformities (LOE 5).(26) Approximately 66% of patients with Marfan syndrome have pectus excavatum or pectus carinatum (LOE 5).”
InfluentialPadberg, J., & Bauer, T. (2006) · doi:10.1055/s-2006-955015 · Cited by 1
Heated, humidified air for the common cold.
Singh, M. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001728.pub3 · Cited by 1
Topical decongestants in otorhinolaryngologist practice
Krivopalov, A. A., & Shamkina, P. A. (2021) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2020-21-84-89
Complex treatment of diseases of the nasal cavity and paranasal sinuses at the present time
Svistushkin, V., & Eremeeva, K. (2021) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2021-18-134-139
Nasal decongestants in the treatment of nasal obstruction
Nikitin, K. A., & Baranskaya, S. (2021) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2021-6-120-124
Larem, A., Aljariri, A. A., Ghannam, M., Aly, A., Mohammed, S., & Shabana, S. (2020) · Textbook of Clinical Otolaryngology · doi:10.1007/978-3-030-54088-3_52
“Over-the-counter decongestants for infants with common cold” – A pediatrician’s dilemma!
Sharma, S. (2020) · Indian Journal of Child Health · doi:10.32677/ijch.2020.v07.i06.001 · Cited by 1 · see citing works
“symptoms, according to the three meta-analyses [21-23] and a”
BackgroundMethodViral Upper Respiratory Infection
Barrett, B. P. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1793-8.00016-9 · Cited by 1 · see citing works
Viral Upper Respiratory Infection
Barrett, B. P. (2007) · Elsevier eBooks · doi:10.1016/b978-1-4160-2954-0.50024-7 · Cited by 8 · see citing works
Therapy of acute upper respiratory tract infections
Schalek, P. (2018) · Praktické lékárenství · doi:10.36290/lek.2018.022
“snižují otok nosní sliznice a mají tak pozitivní vliv na nosní průchodnost (14), je třeba mít v patrnosti jejich možné lékové interakce (antihypertenziva, tricyklická antidepresiva) a kontraindikace (diabe”
Antigripales y vasoconstrictores
Sánchez, L., Velázquez, C., & Hernández, S. (2012) · doi:10.1016/s1134-2072(12)70488-7
Turner, R. (2012) · Goldman's Cecil Medicine · doi:10.1016/b978-1-4377-1604-7.00369-9
Park, K. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0755-7.00371-7
Infecciones virales de las vías respiratorias altas
Barrett, B. P. (2009) · Elsevier eBooks · doi:10.1016/b978-84-458-1911-1.50020-8 · Cited by 1 · see citing works
Arroll, B. (2005) · Clinical evidence · doi:10.1002/0471743984.vse1932
“Decongestants for short-term relief One already-included systematic review updated, benefits and harms data enhanced; [11] categorisation unchanged (Likely to be beneficial).”
BackgroundInfluentialTest Your Knowledge: Ten Questions about the Common Cold
Yamey, G. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020217
Entzündliche Erkrankungen der Nase und der Nasennebenhöhlen
Klimek, L. (2019) · Pädiatrische HNO-Heilkunde · doi:10.1016/b978-3-437-24661-6.00027-1
Graffelman, A. W., & Eekhof, J. (2016) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-1386-0_61
Arroll, B. (2011) · Clinical evidence · doi:10.1016/b978-1-4557-0790-4.00106-2
“08 Objective nasal airways resistance , 3 to 10 hours with single dose of decongestant (oral norephedrine, topical 606 adults 6 RCTs in this analysis [11]”
BackgroundInfluentialSmith, R. P. (2007) · Primary Care in Obstetrics and Gynecology · doi:10.1007/978-0-387-32328-2_19
Arzneiverordnungen im Kindesalter
Schwabe, U. (2006) · doi:10.1007/3-540-30505-x_53
- Authors
- Taverner, D., & Latte, G. J.
- Affiliations
- Royal Adelaide Hospital (AU)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- John Wiley & Sons, Ltd
- Published
- 2007-01-24
- Issue
- 1
- Pages
- CD001953-CD001953
- ISSN
- 1361-6137 (ISSN-L)
- OpenAlex
- W2111275099
- Cited by
- 134
- References
- 59
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 4 · 2021: 5 · 2020: 3 · 2019: 2 · 2018: 7 · 2017: 7 · 2016: 5 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 9
- Type
- reference entry
- Language
- en
- Status
- Retracted
- Update notices
- withdrawal (2009-04-15)
- Open access
- closed
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Complementary and alternative medicine › Herbal Medicine Research Studies
- Health Sciences › Health Professions › Emergency Medical Services › Pediatric health and respiratory diseases
- Keywords
- nasal decongestants, common cold, nasal congestion, pseudoephedrine, adverse effects, insomnia, children, adults, symptom relief, repeated dosing, topical decongestants, oral decongestants, drug safety in children, rhinovirus infection, pharmacodynamics
- MeSH terms
- Adult, Child, Common Cold, Female, Humans, Male, Nasal Decongestants, Randomized Controlled Trials as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
