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Cited by 143Pressure Ulcer Prevention and ManagementClinical Nutrition and GastroenterologyWound Healing and Treatments

Nutritional interventions for preventing and treating pressure ulcers

Langer, Gero, Knerr, Astrid, Kuss, Oliver, Behrens, Johann, Schlömer, Gabriele J·2003·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd003216
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Abstract

BACKGROUND: Pressure ulcers affect 10% of people in hospitals and older people are at highest risk. The correlation between nutritional intake and the development of pressure ulcers is suggested by several studies, but the results are inconsistent. OBJECTIVES: To evaluate the effectiveness of enteral and parenteral nutrition on the prevention and treatment of pressure ulcers. SEARCH STRATEGY: The Cochrane Wounds Group Specialised Trials Register and the Cochrane Central register of Controlled Trials were searched in September 2002. An additional search of PubMed and Cinahl and hand search of conference proceedings and journals was performed, bibliographies of relevant articles were examined and experts in the field as well as manufacturers were contacted in order to find additional literature that may be relevant. SELECTION CRITERIA: Randomised controlled trials evaluating the effectiveness of enteral or parenteral nutrition on the prevention and treatment of pressure ulcers by measuring the incidence of new ulcers, ulcer healing or changes in pressure ulcer severity. There were no restrictions on patients, setting, date, publication status or language. DATA COLLECTION AND ANALYSIS: Abstracts were independently inspected and full articles were obtained of potentially relevant studies. In case of disagreement advice was sought from a third person (AK). Data extraction and assessment of quality were undertaken by the three reviewers independently. MAIN RESULTS: Only 8 randomised controlled trials out of 16 potentially relevant articles were included. However, most of the 8 trials included are small and of poor methodological quality. PREVENTION: Four studies compared a combination of nutritional supplements, consisting of a minimum of energy and protein in different dosages, for the prevention of pressure ulcers. The largest study found that nutritional supplements reduced the number of new pressure ulcers (Bourdel-M 2000). The three smaller studies lacked power. TREATMENT: Four studies evaluated the effects of nutritional supplements for the treatment of existing pressure ulcers: one trial examined mixed nutritional supplements, one trial examined zinc, another the effect of proteins, and two studies compared ascorbic acid. The trials included are heterogeneous with regard to participants, interventions and outcomes; therefore it was considered inappropriate to perform a meta-analysis. REVIEWER'S CONCLUSIONS: It was not possible to draw any firm conclusions on the effect of enteral and parenteral nutrition on the prevention and treatment of pressure ulcers. Further trials of high methodological quality are necessary.

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  • There is evidence that ACE inhibitors may halt or slow the decline in muscle strength in older age.

    “there is evidence that ACE inhibitors may halt or slow the decline in muscle strength in older age (129)”

    From Frailty in elderly people (2013) · cites this paper as [129]

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Authors
Langer, G., Knerr, A., Kuss, O., Behrens, J., & Schlömer, G. J.
Affiliations
  • Martin Luther University Halle-Wittenberg (DE)
  • Universität Hamburg (DE)
ORCID
Venue
Cochrane Database of Systematic Reviews
Publisher
John Wiley & Sons, Ltd
Published
2003-10-20
Issue
4
Pages
CD003216-CD003216
ISSN
1361-6137 (ISSN-L)
DOI
10.1002/14651858.cd003216
OpenAlex
W4237874047
Cited by
143
References
26
Citations by year
2026: 1 · 2025: 4 · 2024: 4 · 2023: 7 · 2022: 3 · 2021: 5 · 2020: 3 · 2019: 3 · 2018: 7 · 2017: 4 · 2016: 6 · 2015: 13 · 2014: 13 · 2013: 11 · 2012: 11
Type
reference entry
Language
en
Update notices
new_version (2014-06-12)
Open access
closed
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Health Professions › Occupational Therapy › Pressure Ulcer Prevention and Management
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
Keywords
pressure ulcers, enteral nutrition, parenteral nutrition, dietary supplements, pressure ulcer prevention, pressure ulcer treatment, zinc supplementation, protein supplementation, vitamin C, wound healing, older adults, hospitalized patients
MeSH terms
Aged, Pressure Ulcer, Enteral Nutrition, Humans, Parenteral Nutrition, Randomized Controlled Trials as Topic

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