The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease
Abstract
BACKGROUND: Non-invasive positive pressure ventilation (NPPV) is being used increasingly in the management of patients admitted to hospital with acute respiratory failure secondary to an exacerbation of chronic obstructive pulmonary disease (COPD). OBJECTIVES: To determine the efficacy of NPPV in the management of patients with respiratory failure due to an acute exacerbation of COPD. SEARCH STRATEGY: An initial search was performed using the Cochrane Airways Group trials register and other relevant electronic databases. An updated search was conducted in September 2003 and another in April 2004. SELECTION CRITERIA: Randomised controlled trials comparing NPPV plus usual medical care (UMC) versus UMC alone were selected. Trials needed to recruit adult patients admitted to hospital with respiratory failure due to an exacerbation of COPD and with PaCO2 > 6 kPa (45 mmHg). DATA COLLECTION AND ANALYSIS: Two reviewers independently selected articles for inclusion, evaluated methodological quality of the studies and abstracted the data. MAIN RESULTS: Fourteen studies were included in the review. NPPV resulted in decreased mortality (Relative Risk 0.52; 95%CI 0.35 to 0.76), decreased need for intubation (RR 0.41; 95%CI 0.33 to 0.53), reduction in treatment failure (RR 0.48; 95%CI 0.37 to 0.63), rapid improvement within the first hour in pH (Weight Mean Difference 0.03; 95%CI 0.02 to 0.04), PaCO2 (WMD -0.40 kPa; 95%CI -0.78 to -0.03) and respiratory rate (WMD -3.08 bpm; 95%CI -4.26 to -1.89). In addition, complications associated with treatment (RR 0.38; 95%CI 0.24 to 0.60) and length of hospital stay (WMD -3.24 days; 95%CI -4.42 to -2.06) was also reduced in the NPPV group. REVIEWERS' CONCLUSIONS: Data from good quality randomised controlled trials show benefit of NPPV as first line intervention as an adjunct therapy to usual medical care in all suitable patients for the management of respiratory failure secondary to an acute exacerbation of COPD. NPPV should be considered early in the course of respiratory failure and before severe acidosis ensues, as a means of reducing the likelihood of endotracheal intubation, treatment failure and mortality.
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Cites
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Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
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Cited by
Evolution of Mortality over Time in Patients Receiving Mechanical Ventilation
Esteban, A., Frutos-Vivar, F., Muriel, A., Ferguson, N. D., Peñuelas, O., Abraira, V., Raymondos, K., Rios, F., Nin, N., Apezteguía, C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201212-2169oc · Cited by 676
Guidelines for the physiotherapy management of the adult, medical, spontaneously breathing patient
Bott, J., Blumenthal, S., Buxton, M., Ellum, S., Falconer, C., Garrod, R., Harvey, A., Hughes, T., Lincoln, M., Mikelsons, C., et al. (2009) · Thorax · doi:10.1136/thx.2008.110726 · Cited by 451
COPD Guidelines: A Review of the 2018 GOLD Report
Mirza, S., Clay, R. D., Koslow, M. A., & Scanlon, P. D. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.05.026 · Cited by 444
BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults
Davidson, A. C., Banham, S., Elliott, M., Kennedy, D., Gelder, C., Glossop, A., Church, A. C., Creagh-Brown, B., Dodd, J. W., Felton, T., et al. (2016) · Thorax · doi:10.1136/thoraxjnl-2015-208209 · Cited by 426
Osadnik, C. R., Tee, V. S., Carson-Chahhoud, K. V., Picot, J., Wedzicha, J. A., & Smith, B. J. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004104.pub4 · Cited by 422
Self-citation
Metadata
- Authors
- Ram, F. S., Picot, J., Lightowler, J., & Wedzicha, J. A.
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- John Wiley & Sons, Ltd
- Published
- 2004-07-19
- Issue
- 3
- Pages
- CD004104-CD004104
- ISSN
- 1361-6137 (ISSN-L)
- OpenAlex
- W2124129697
- Cited by
- 552
- References
- 73
- Type
- reference entry
- Language
- en
- Open access
- closed
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