Cited by 101Intensive Care Unit Cognitive DisordersGeriatric Care and Nursing HomesDementia and Cognitive Impairment Research

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Interventions for preventing delirium in older people in institutional long-term care

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Clegg, Andrew, Siddiqi, Najma, Heaven, Anne, Young, John, Holt, Rachel·2014·Cochrane Database of Systematic Reviews

DOI 10.1002/14651858.cd009537.pub2PMC PMC6478111

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Abstract

Background Delirium is a common and distressing complication of a range of stressor events including infection, new medications and environment change that is often experienced by older people with frailty and dementia. Older people living in institutional long-term care (LTC)are at high risk of delirium, which increases the risk of admission to hospital, development of or worsening of dementia, and mortality.Delirium is also associated with substantial healthcare costs. Although it is possible to prevent delirium in the hospital setting by providing multicomponent delirium prevention interventions it is currently unclear whether interventions to prevent delirium in LTCare effective. Objectives To assess the effectiveness of interventions for preventing delirium in older people in long term care. Search methods We searched ALOIS (www.medicine.ox.ac.uk/alois) - the Cochrane Dementia and Cognitive Improvement Group's Specialised Register- on 23 April 2013. The search was as sensitive as possible to identify all studies on ALOIS relating to delirium. We ran additional separate searches in major healthcare databases, trial registers, the Cochrane Central Register of Controlled Trials (CENTRAL) and grey literature sources, to ensure that the search was as comprehensive as possible. Selection criteria We included randomised controlled trials (RCTs) and cluster-randomised controlled trials (cluster-RCTs) of single- and multi componentn on-pharmacological and pharmacological interven…

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Authors: Clegg, A., Siddiqi, N., Heaven, A., Young, J., & Holt, R.
Affiliations: University of Leeds (GB)
Bradford Institute for Health Research (GB)
Bradford Royal Infirmary (GB)
ORCID: Clegg, Andrew
Siddiqi, Najma
Heaven, Anne
Young, John
Venue: Cochrane Database of Systematic Reviews
Publisher: Wiley
Published: 2014-01-31
Volume: 4
Issue: 1
Pages: CD009537-CD009537
ISSN: 1361-6137 (ISSN-L)
1465-1858
DOI: 10.1002/14651858.cd009537.pub2
PMC: PMC6478111
OpenAlex: W1567489802
Cited by: 100
References: 63
Citations by year: 2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 14 · 2021: 9 · 2020: 16 · 2019: 11 · 2018: 7 · 2017: 11 · 2016: 7 · 2015: 7 · 2014: 6
FWCI: 1.62
Type: journal article
Language: en
Update notices: new_version (2019-04-23)
Open access: green
www.ncbi.nlm.nih.gov
Locations: Cochrane Database of Systematic Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute for Health and Care Research (PB-PG-0610-22068)
Topics: Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: delirium prevention, long-term care facilities, older adults, non-pharmacological treatment, hydration, dementia, activities of daily living, quality of life, frailty, nursing homes, delirium incidence, delirium severity, dementia incidence, adverse outcomes, risk of bias, trial reporting quality, multicomponent intervention, pharmacological interventions, mortality, health care costs
MeSH terms: Aged, Delirium, Fluid Therapy, Humans, Institutionalization, Long-Term Care, Randomized Controlled Trials as Topic, Frail Elderly, Medication Reconciliation

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Interventions for preventing delirium in older people in institutional long-term care

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