The DOI matches its Crossref record; 196 of the 199 references it cites were found in a registry or an index.
Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults
Open accessAbstract
BACKGROUND: Medically unexplained physical symptoms (MUPS) are physical symptoms for which no adequate medical explanation can be found after proper examination. The presence of MUPS is the key feature of conditions known as 'somatoform disorders'. Various psychological and physical therapies have been developed to treat somatoform disorders and MUPS. Although there are several reviews on non-pharmacological interventions for somatoform disorders and MUPS, a complete overview of the whole spectrum is missing. OBJECTIVES: To assess the effects of non-pharmacological interventions for somatoform disorders (specifically somatisation disorder, undifferentiated somatoform disorder, somatoform disorders unspecified, somatoform autonomic dysfunction, pain disorder, and alternative somatoform diagnoses proposed in the literature) and MUPS in adults, in comparison with treatment as usual, waiting list controls, attention placebo, psychological placebo, enhanced or structured care, and other psychological or physical therapies. SEARCH METHODS: We searched the Cochrane Depression, Anxiety and Neurosis Review Group's Specialised Register (CCDANCTR) to November 2013. This register includes relevant randomised controlled trials (RCTs) from The Cochrane Library, EMBASE, MEDLINE, and PsycINFO. We ran an additional search on the Cochrane Central Register of Controlled Trials and a cited reference search on the Web of Science. We also searched grey literature, conference proceedings, international trial registers, and relevant systematic reviews. SELECTION CRITERIA: We included RCTs and cluster randomised controlled trials which involved adults primarily diagnosed with a somatoform disorder or an alternative diagnostic concept of MUPS, who were assigned to a non-pharmacological intervention compared with usual care, waiting list controls, attention or psychological placebo, enhanced care, or another psychological or physical therapy intervention, alone or in combination. DATA COLLECTION AND ANALYSIS: Four review authors, working in pairs, conducted data extraction and assessment of risk of bias. We resolved disagreements through discussion or consultation with another review author. We pooled data from studies addressing the same comparison using standardised mean differences (SMD) or risk ratios (RR) and a random-effects model. Primary outcomes were severity of somatic symptoms and acceptability of treatment. MAIN RESULTS: We included 21 studies with 2658 randomised participants. All studies assessed the effectiveness of some form of psychological therapy. We found no studies that included physical therapy.Fourteen studies evaluated forms of cognitive behavioural therapy (CBT); the remainder evaluated behaviour therapies, third-wave CBT (mindfulness), psychodynamic therapies, and integrative therapy. Fifteen included studies compared the studied psychological therapy with usual care or a waiting list. Five studies compared the intervention to enhanced or structured care. Only one study compared cognitive behavioural therapy with behaviour therapy.Across the 21 studies, the mean number of sessions ranged from one to 13, over a period of one day to nine months. Duration of follow-up varied between two weeks and 24 months. Participants were recruited from various healthcare settings and the open population. Duration of symptoms, reported by nine studies, was at least several years, suggesting most participants had chronic symptoms at baseline.Due to the nature of the intervention, lack of blinding of participants, therapists, and outcome assessors resulted in a high risk of bias on these items for most studies. Eleven studies (52% of studies) reported a loss to follow-up of more than 20%. For other items, most studies were at low risk of bias. Adverse events were seldom reported.For all studies comparing some form of psychological therapy with usual care or a waiting list that could be included in the meta-analysis, the psychological therapy resulted in less severe symptoms at end of treatment (SMD -0.34; 95% confidence interval (CI) -0.53 to -0.16; 10 studies, 1081 analysed participants). This effect was considered small to medium; heterogeneity was moderate and overall quality of the evidence was low. Compared with usual care, psychological therapies resulted in a 7% higher proportion of drop-outs during treatment (RR acceptability 0.93; 95% CI 0.88 to 0.99; 14 studies, 1644 participants; moderate-quality evidence). Removing one outlier study reduced the difference to 5%. Results for the subgroup of studies comparing CBT with usual care were similar to those in the whole group.Five studies (624 analysed participants) assessed symptom severity comparing some psychological therapy with enhanced care, and found no clear evidence of a difference at end of treatment (pooled SMD -0.19; 95% CI -0.43 to 0.04; considerable heterogeneity; low-quality evidence). Five studies (679 participants) showed that psychological therapies were s
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Cognitive behavioral therapy (CBT) has been shown effective for health anxiety [17] and seems promising for PPS, although, with generally modest effects and limited data on environmental intolerance [18].”
From Work Ability and Functioning Among Individuals with Persistent Indoor Environment-Related Symptoms or Chronic Fatigue: Nine-Month Follow-Up of a Web-Based Randomized Controlled Trial. (2026) · cites this paper as [18]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Similarly, CBT has shown more pronounced effects on diagnosed health anxiety [17] than PPS [18].”
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Selection bias may exist due to voluntary enrollment, as intervention studies in general [18], and only those capable of using the online program via computer or smartphone could participate, affecting representativeness.”
From Work Ability and Functioning Among Individuals with Persistent Indoor Environment-Related Symptoms or Chronic Fatigue: Nine-Month Follow-Up of a Web-Based Randomized Controlled Trial. (2026) · cites this paper as [18]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
(1992) · PubMed · Cited by 33,716
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
Flagged first, then by citations
3 of the 199 references couldn’t be matched to a known paper.
Research works printed but not linked: 34
- Allen L A new treatment for somatization disorder. Proceedings of the World Psychiatric Association, International Congress; 2006 Jul 12-16; Istanbul, Turkey 2006
- Escobar JI An effective intervention for medically unexplained symptoms in primary care. Proceedings of the World Psychiatric Association, International Congress; 2006 Jul 12-16; Istanbul, Turkey 2006
- Escobar, 2007, Treatment of patients presenting with unexplained physical symptoms in primary care, Neuropsychopharmacology, 29 Suppl 1, S101
- Fjorback, 2012, Mindfulness therapy for Bodily distress syndrome: Economic evaluation alongside a randomized trial, Journal of Psychosomatic Research, 72, 480
- Fjorback, 2012, Mindfulness therapy for Bodily distress syndrome - randomized trial, one-year follow-up, active control, Journal of Psychosomatic Research, 72, 480
- Lahmann, 2007, PISO - an evidence-based approach in the therapy of somatoform disorders, PDP Psychodynamische Psychotherapie, 6, 131
- Speckens, 1996, Favourable effects of cognitive behavioural therapy on unexplained physical symptoms: A randomized trial, Nederlands Tijdschrift voor Geneeskunde, 140, 1227
- Ravesteijn, 2012, Mindfulness training for patients with medically unexplained symptoms in primary care, an RCT, Journal of Psychosomatic Research, 72, 506
- Blankenstein, 2001, Somatisation in General Practice. Reattribution, a Promising Approach [thesis]
- Gottschalk, 2011, Cognitive-behavioral therapy enriched with emotion regulation training (ENCERT) in patients with multiple somatoform symptoms: preliminary findings, Verhaltenstherapie, 21 Suppl 1, 1
- Pols RG Battersby M Searcy D Hawkins R Mahoney S Allen K A controlled trial of coordinated care for somatisation disorders. Proceedings of the WPA, Section of Epidemiology and Community Psychiatry Symposium; 1997 Oct 19-22; Sydney, Australia 1997
- Van der Feltz-Cornelis CM Van Oppen P Ader H Van Dyk R Psychiatric consultation for somatoform disorder in primary care. Proceedings of the 157th Annual Meeting of the American Psychiatric Association; 2004 May 1-6; New York 2004
- Wiefferink, 1997, Effect of a psychiatric intervention, aimed at the family situation, at the consumption of care by somatic patients, Tijdschrift voor Sociale Gezondheidszorg, 1, 31
- Burwell-Walsh, 2002, Emotion-Focused Couples Therapy as a Treatment of Somatoform Disorders: an Outcome Study [Doctoral dissertation]
- Mussgay, 2006, Effects of aerobic exercise on autonomic dysregulation in patients with anxiety and somatization disorders, 183
- Woolfolk, 2007, Clinical trial assessing the efficacy of affective cognitive-behavioral therapy, 165
- Agger JL Treatment of multi-organ bodily distress syndrome. A randomized controlled trial of the effects of acceptance and commitment therapy given as group therapy or workshop compared to standard treatment (Stress-4) clinicaltrials.gov/show/NCT01518647
- Sitnikova, Cost-effectiveness of a short-term cognitive-behavioural intervention by mental health nurse practitioners for primary care patients with an undifferentiated somatoform disorder - CIPRUS, http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4686
- American Psychiatric Association, 1980, Diagnostic and Statistical Manual of Mental Health Disorders
- American Psychiatric Association, 2000, Diagnostic and Statistical Manual of Mental Health Disorders
- Chernyak, 2014, Economic evaluation of brief psychodynamic interpersonal therapy in patients with multisomatoform disorder, PLoS One, 22, e83894, 10.1371/journal.pone.0083894 · DOI
- Derogatis, 1986, The SCL-90-R: Administration, Scoring, and Procedures Manual II
- First, 2002, Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition
- Gili, 2014, Health related quality of life changes in somatising patients after individual versus group cognitive behavioural therapy: a randomized clinical trial, Journal of Psychosomatic Research, 76, 89, 10.1016/j.jpsychores.2013.10.018 · DOI
- Guy, 1976, 028 CGI Clinical Global Impressions, 218
- Hakkaart-van Roijen, 2002, Trimbos/iMTA Questionnaire for Costs Associated with Psychiatric Illness (TiC-P)
- Nanke, 2003, Biofeedback-based interventions in somatoform disorders: a randomized controlled trial, Acta Neuropsychiatrica, 15, 249, 10.1034/j.1601-5215.2003.00028.x · DOI
- The Nordic Cochrane Centre, The Cochrane Collaboration Review Manager (RevMan) 2012
- Rief, 1997, SOMS: Das Screening für Somatoforme Störungen [SOMS: Screening for Somatoform Disorders]
- Spitzer, 1990, Structured Clinical Interview for DSM-III-R
- Ravensteijn, 2013, Mindfulness-based cognitive therapy for patients with medically unexplained symptoms: a randomized controlled trial, Psychotherapy and Psychosomatics, 82, 299, 10.1159/000348588 · DOI · Paper page
- World Health Organization, 1975, International Statistical Classification of Diseases and Related Health Problems
- World Health Organization, 1990, Composite International Diagnostic Interview
- Zaby, 2008, Waiting, relaxation, or cognitive-behavioral therapy - how effective is outpatient group therapy for somatoform symptoms?, Zeitschrift für Klinische Psychologie und Psychotherapie, 37, 15, 10.1026/1616-3443.37.1.15 · DOI
Cited by
Sorted by citations
Items 201–300 of 303
Yoshiike, T., Kuriyama, K., Nakasato, Y., & Nakamura, M. (2020) · Journal of Behavioral and Cognitive Therapy · doi:10.1016/j.jbct.2020.03.012 · Cited by 2
Funktionelle Störungen – somatoforme Störungen
Langewitz, W. A., & Degen, L. P. (2016) · Elsevier eBooks · doi:10.1016/b978-3-437-21833-0.00066-8 · Cited by 3
Kleinstäuber, M., & Rief, W. (2015) · doi:10.1002/9781394259229.ch16 · Cited by 3
Self-citationInternal medicine at the crossroads of long COVID diagnosis and management
Ranque, B., & Cogan, E. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1521472 · Cited by 2
Transdiagnostic approach to understanding persistent physical symptoms
Felton, L., Mahalingappa, S. S., Husain, M., & Chalder, T. (2025) · BJPsych Advances · doi:10.1192/bja.2025.10145 · Cited by 2
“In a Cochrane review, van Dessel et al (2014) found CBT to be more effective than control conditions in reducing psychological distress and improving medical status of people with PPS.”
Gouraud, C., Ancellin-Geay, A., Verot, C., Bergeras, I., Poudevigne, L., Cormier, L., Gilbert, S., Limosin, F., Lacoste, L., Ribayrol, D., et al. (2025) · BMC Psychology · doi:10.1186/s40359-025-03820-8 · Cited by 2
Randomized controlled trial protocol of health coaching for veterans with complex chronic pain
Crosky, S., McFarlin, M. L., Sullivan, N. L., Winograd, D. M., Litke, D. R., Masheb, R. M., Lu, S., Costanzo, M. E., Anastasides, N., Gonzalez, C., et al. (2023) · Trials · doi:10.1186/s13063-023-07113-6 · Cited by 2
“Considering that CMI is reactive to placebo interventions [60], it will be difficult to interpret the results of a comparative effectiveness trial without knowing if health coaching is more effective than a placebo.”
BackgroundBratty, A. J. (2023) · PubMed Central · Cited by 2
Abrahamsen, C., Wangen, K. R., Lindbæk, M., & Werner, E. L. (2024) · BJGP Open · doi:10.3399/bjgpo.2024.0004 · Cited by 2
Mehta, U. M., & Chaturvedi, S. K. (2022) · doi:10.1093/med/9780198861478.003.0044 · Cited by 2
Somatoforme Störungen - der Körper spiegelt die Last der Seele
Kunzel, H. E. (2022) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-022-1802-2 · Cited by 2
Evidenzbasierte Therapie somatoformer Störungen
Depping, M. K., & Löwe, B. (2018) · PSYCH up2date · doi:10.1055/s-0043-121603 · Cited by 2
The reasons for an unjustified visit by patients with somatoform disorders to general practitioners
Погосов, А. В., Борисович, Л. В., & Bogushevskaya, Y. V. (2018) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2018-4-40-45 · Cited by 2
Карпушкин, А. М., & Овчинников, А. А. (2022) · Сибирский вестник психиатрии и наркологии · doi:10.26617/1810-3111-2021-4(113)-79-92 · Cited by 2
Somatic symptom disorder in primary care: A collaborative approach
Pilipenko (2022) · The Journal of Family Practice · doi:10.12788/jfp.0384 · Cited by 3
The Relationship Between Body Mass Index and Body Dysmorphic Disorder in Adolescents
Aritonang, C. R. L., & Munthe, R. V. (2022) · International Journal of Health Sciences and Research · doi:10.52403/ijhsr.20221225 · Cited by 2
“In the Diagnostic and Statistical Manual of Mental Disorders, revised III edition (DSM-III-R) and DSM IV, BDD is included in the somatoform disorder, which means complaints or physical symptoms that give the impression of a physical disorder, without which the disorder can be found objectively, or no mechanism can exp…”
BackgroundChapman, A., Poliakoff, E., Chew-Graham, C., & Brown, R. J. (2018) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2018.08.002 · Cited by 2
“, reporting disproportionate numbers of symptoms) are well documented [8, 9], they remain poorly understood and existing interventions only produce modest improvements [10-13].”
BackgroundRathod, D., Xu, B., Filipi, Z. S., & Hoffman, M. (2020) · SAE International Journal of Engines · doi:10.4271/03-13-04-0029 · Cited by 2
Functional Symptoms and Disorders
Hulgaard, D. R. (2020) · Wiley eBooks · doi:10.1002/9781119438519.ch100 · Cited by 2
Modern approaches to psychoterapy of somatoform disorders
Mukhametova, A. I., & Vasilyev, V. V. (2024) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2024-907 · Cited by 1
Hüsing, P., & Löwe, B. (2025) · Verhaltenstherapie · doi:10.1159/000542766 · Cited by 1
Eichhorn, H., Leydecker, L. E., Brand, S., & Jungmann, S. M. (2025) · BMC Psychology · doi:10.1186/s40359-025-03705-w · Cited by 1
“At the same time the treatment of somatic symptom disorder shows only small to medium effects [2, 3] and mechanisms behind the emergence of somatic symptoms are not yet fully understood [4].”
Hammerman, O., Rasooly, A., Greenberg, D., Kushnir, T., Yaakobi, E., & Ezra, Y. (2026) · Israel Journal of Health Policy Research · doi:10.1186/s13584-026-00750-7 · Cited by 1
“Clinical guidelines recommend multidisciplinary care for FSD, integrating medical management with non-pharmacological approaches, including mind–body therapies (MBT) such as hypnotherapy, cognitive behavioral therapy, mindfulness meditation, and pain reprocessing therapy [6, 7].”
A Brief Review of Physical and Psychosocial Factors Involved in Chronic Low Back Pain
Rishiraj, N. (2015) · Occupational Medicine & Health Affairs · doi:10.4172/2329-6879.1000201 · Cited by 1
Cochrane Insurance Medicine (CIM): bekendheid en interesse onder verzekeringsartsen
Hoving, J. L., Cornelius, B., de Boer, W. E. L., Kok, R., Brouwer, S., & Schaafsma, F. G. (2017) · Tijdschrift voor bedrijfs- en verzekeringsgeneeskunde · doi:10.1007/s12498-017-0003-x · Cited by 1
Chapitre 15 – Troubles somatoformes et intrications médicopsychiatriques
Hardy, P. (2017) · doi:10.1016/b978-2-294-74927-8.00015-2 · Cited by 1
Lennox, G. A. K., & Kendall, R. (2019) · European Journal of Emergency Medicine · doi:10.1097/mej.0000000000000613 · Cited by 1
Treatment-associated network dynamics in patients with globus sensations: a proof-of-concept study
Imperiale, M. N., Lieb, R., & Meinlschmidt, G. (2023) · Scientific Reports · doi:10.1038/s41598-023-42186-y · Cited by 1
Disorders of Bodily Distress and Bodily Experience
Feltz-Cornelis, C. M. V. D. (2023) · Springer eBooks · doi:10.1007/978-3-030-42825-9_99-1 · Cited by 1
Psychotherapie bei Somatischer Belastungsstörung
Kleinstäuber, M. (2024) · PiD - Psychotherapie im Dialog · doi:10.1055/a-2249-8180 · Cited by 1
Self-citationDaehler, S., Lutz, W., Probst, T., Rief, W., Rubel, J. A., Schwartz, S., & Kleinstäuber, M. (2025) · Cognitive Therapy and Research · doi:10.1007/s10608-024-10571-0 · Cited by 1
“A different meta-analysis of 21 studies including 2658 patients found that CBT significantly reduced somatic symptom severity by the end of treatment (van Dessel et al., 2014).”
InfluentialSelf-citationBoluda-Verdú, I., & Catalá-López, F. (2025) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2025.102457 · Cited by 3
“De ellas, tres presentaron resultados favora-bles respecto al comparador y en una fueron neutros/no concluyentes por alta heterogeneidad .”
Gulati, K., Gunasekaran, D. M., Bhargav, H., Bhaskarapillai, B., Nanjaiah, N. D., Varambally, S. S., Gangadhar, B. N., & Desai, G. (2025) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry.indianjpsychiatry_932_24 · Cited by 1
Neuropsychological Assessment and Management of Older Adults with Multiple Somatic Symptoms
Lamberty, G. J., & Bares, K. K. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3106-0_9 · Cited by 1
When Trauma Is in the Body: Managing Physical Concerns
Greenberg, T. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-45285-8_7 · Cited by 1
Does it mean anything to diagnose fibromyalgia (FM) in somebody with chronic widespread pain?
Catoggio, L. J. (2015) · Clinical Rheumatology · doi:10.1007/s10067-015-2982-2 · Cited by 1
Somatic symptom and related disorders
Murray, A., Toussaint, A. C., & Löwe, B. (2017) · doi:10.1093/med/9780198746638.003.0013 · Cited by 1
Medically Unexplained Symptoms
FHEA, G. G. M. M. F. F. P. (., GradDipUTL, W. C. M. B. B. D. D. M. M. M., & FTCD, B. D. K. M. B. B. M. M. M. M. P. D. P. M. (. O. M. F. F. (2021) · Wiley eBooks · doi:10.1002/9781394322978.ch23 · Cited by 1
Terapia cognitivo conductual para los trastornos de ansiedad en niños y adolescentesPreprint
Hechenleitner, G., Ruiz, P., Cortés-Jofré, M., & Ortiz-Muñoz, L. E. (2023) · doi:10.31219/osf.io/zkd7b · Cited by 1
Röhricht, F., Green, C., Filippidou, M., Lowe, S., Power, N., Rassool, S., Rothman, K., Shah, M., & Papadopoulos, N. L. R. (2024) · Research Square · doi:10.21203/rs.3.rs-3939984/v1 · Cited by 1
Vuokko, A., Immonen, M., Lappalainen, P., Keinonen, K., Sainio, M., Lappalainen, R., Paunio, T., & Selinheimo, S. (2026) · Journal of Occupational Rehabilitation · doi:10.1007/s10926-026-10400-z
Veselinović, T., & Schneider, F. W. (2015) · Springer eBooks · doi:10.1007/978-3-642-54571-9_18
Movement Aberrations in Patients with Long Lasting Subacromial Impingement Syndrome
Berg, V. K. (2014) · NORA - Norwegian Open Research Archives
SOLK hoeft niet naar de psycholoog
Houwen, J., & Hartman, T. O. (2015) · Huisarts en Wetenschap · doi:10.1007/s12445-015-0357-1
Les troubles somatoformes : quelles approches psychothérapeutiques ?
Rapoport-Hubschman, N. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.09.118
‘Zakendoen met emoties’, besparen op verzuim?
Homeijer, I. (2016) · Tijdschrift voor bedrijfs- en verzekeringsgeneeskunde · doi:10.1007/s12498-016-0165-y
Een goede arts-patiëntrelatie bij SOLK is van belang
Weiland, A. (2017) · Praktische huisartsgeneeskunde · doi:10.1007/978-90-368-0639-8_5
Premature Ejaculation: A Redundant Entity in the Era of Somatic Symptom Disorder?
Pal, A., & Acharya, R. (2017) · Indian Journal of Psychological Medicine · doi:10.4103/0253-7176.207324
“[2] This is very similar to the etiopathological model of somatic symptoms.[6] The treatment of both the disorders”
ResultDe somatische symptoom- en aanverwante stoornissen en persoonlijkheidspathologie
Kooiman, K. (2017) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-0931-3_27
Management der somatischen Belastungsstörung
Roenneberg, C., & Henningsen, P. (2016) · NeuroTransmitter · doi:10.1007/s15016-016-5397-7
“Bei kurzen «erapiedauern zeigten sich jedoch nur kleine Eekte [7, 8].”
Background8.6 Somatisch symptoomsyndroom
Feltz-Cornelis, C. M. V. D. (2017) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2052-3_36
Functional (Medically Unexplained) Physical Syndromes/Symptoms: The Cognitive Behavioral Perspective
Karademas, E. C. (2018) · Springer eBooks · doi:10.1007/978-3-319-89360-0_3
Medizinisch nicht begründbare Symptome
Reuter, J. (2018) · Elsevier eBooks · doi:10.1016/b978-3-437-15340-2.00018-5
Hartman, T. O., & Tak, L. M. (2018) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2174-2_11
Cognitieve therapie bij ziekteangststoornis en de somatisch-symptoomstoornis
Visser, S., & Reinders, M. (2019) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2021-9_10
Burch, J., & Preda, A. (2019) · Cochrane Clinical Answers · doi:10.1002/cca.2344
Salimi, N. (2018) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Bodily Distress Syndrome (BDS), Bodily Stress Syndrome (BSS) and Health Anxiety in Older Adults
Ivbijaro, G. O., Goldberg, D. P., Kolkiewicz, L., Edwards, T. M., McReynolds, C., & Švab, I. (2019) · Springer eBooks · doi:10.1007/978-3-030-10814-4_15
Trastornos somatomorfos y facticios
Morán, M. T. V., García, L. S. M., & Cabeza, I. G. (2019) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/j.med.2019.07.003
Functional Symptoms and Disorders
Hulgaard, D. R. (2020) · Wiley eBooks · doi:10.1002/9781119788409.ch18
Hughes, T., Meredith, F., Monteregge, S., Bennett, S. D., & Shafran, R. (2020) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465820000752
Carmassi, C., Cappelli, A., Dell’Oste, V., Amatori, G., Bertelloni, C. A., Massimetti, G., Nisita, C., & Dell’Osso, L. (2020) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001288
“In particular, cognitive behavioral therapy (CBT) could help patients change the way they perceive and manage their symptoms and seems to be promising, especially in a multidisciplinary treatment (Houtveen et al., 2015; van Dessel et al., 2014).”
BackgroundDoes CBT decrease physical symptoms in somatic symptom disorder in adults?
O'Hara, M., & Howard, C. J. (2021) · Evidence-Based Practice · doi:10.1097/ebp.0000000000001189
Satô, A., Itagaki, S., Matsumoto, T., Ise, Y., Yokokura, S., Wada, T., Hayashi, K., Kakamu, T., Fukushima, T., Nikaido, T., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-150296/v2
Astenia funcional o síndrome de fatiga crónica
Kachaner, A., & Ranque, B. (2021) · EMC - Tratado de Medicina · doi:10.1016/s1636-5410(21)45104-4
A Review on Cognitive Impairments in Parkinson’s Disease
Sharma, S., Sunil, S., Kochhar, K. P., & Jain, S. (2021) · Acta Scientific Veterinary Sciences · doi:10.31080/asvs.2021.03.0246
Leentjens, A. F. G., & Verhey, F. R. J. (2017) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2052-3_30
Veselinovic, T., & Schneider, F. W. (2016) · Springer eBooks · doi:10.1007/978-3-662-50345-4_27
Satô, A., Itagaki, S., Matsumoto, T., Ise, Y., Yokokura, S., Wada, T., Hayashi, K., Kakamu, T., Fukushima, T., Nikaido, T., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-150296/v1
Therapieansätze für unerklärte Körperbeschwerden und somatoforme Störungen
Kleinstäuber, M., Thomas, P., Witthöft, M., & Hiller, W. F. A. (2017) · Springer eBooks · doi:10.1007/978-3-662-54664-2_3
Self-citationSOLK hoeft niet naar de psycholoog
van Loghum, B. S. (2016) · Huisarts en Wetenschap · doi:10.1007/s12445-016-0079-z
Beperkt effect psychologische behandeling bij SOLK
van Loghum, B. S. (2015) · Huisarts en Wetenschap · doi:10.1007/s12445-015-0356-2
(2016) · Elsevier eBooks · doi:10.1016/b978-3-437-21833-0.16001-2
Neuropsychological Assessment and Management of Older Adults with Multiple Somatic Symptoms
Lamberty, G. J., & Bares, K. K. (2019) · Clinical handbooks in neuropsychology · doi:10.1007/978-3-319-93497-6_21
Mills, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-57111-9_9257
Ramírez-Aranda, J. M., Sanchez, M. S. G., Guedea, M. A. H., Azuara, Y. G. O., Uresti, Y. K. T., & Heredia, S. A. B. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_2254_21
“This represents a challenge for the practicing physician due to the need to normalize the symptom, and the patient can more easily accept alternative treatments in stress management such as mindfulness, physical activity, yoga, speech therapy, among others.[28] This study has implications for the design of interventio…”
BackgroundSatô, A., Itagaki, S., Matsumto, T., Ise, Y., Yokokura, S., Wada, T., Hayashi, K., Kakamu, T., Fukushima, T., Nikaido, T., et al. (2023) · FUKUSHIMA JOURNAL OF MEDICAL SCIENCE · doi:10.5387/fms.2022-04
Clinical impact and misdiagnosis of functional ophthalmological symptoms: a case report
Moyano, B. P., Duquenne, C., Favrat, B., Francois-Xavier, B., Kokkinakis, I., & Tzartzas, K. (2023) · Journal of Medical Case Reports · doi:10.1186/s13256-023-04063-0
“From a therapeutic point of view, meta-analytic evidence supports the efficacy of psychotherapeutic treatment for the somatic syndrome disorder and functional somatic syndromes [16, 27], early psychological interventions being promising but challenging [28].”
BackgroundImproving clinical practice over the years: exploring the Journal archive
Lawson, E., & Khan, N. (2023) · British Journal of General Practice · doi:10.3399/bjgp23x734949
Guthrie, E. (2023) · Cambridge University Press eBooks · doi:10.1017/9781911623533.015
Disorders of Bodily Distress and Bodily Experience
Feltz-Cornelis, C. M. V. D. (2024) · Springer eBooks · doi:10.1007/978-3-030-51366-5_99
Körperliche Aktivität bei der Behandlung psychischer Erkrankungen
Bendau, A., Heuer, S., Meska, S., Terziska, A., & Plag, J. (2024) · Elsevier eBooks · doi:10.1016/b978-3-437-15091-3.00006-7
Zimmer, P. D. C., & Rubín, R. T. (2025) · PLOS mental health. · doi:10.1371/journal.pmen.0000214
General principles of management of somatization
Orsolini, L., Cicolini, A., Salvi, V., & Volpe, U. (2025) · doi:10.1093/med/9780192858290.003.0019
González, I., Melgarejo, O. J., & Torales, J. C. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780192858290.003.0012
Grundlagen der Diagnostik und Therapie
(2024) · Elsevier eBooks · doi:10.1016/b978-3-437-22487-4.16001-0
Naylor, C. (2024) · Springer eBooks · doi:10.1007/978-3-031-25376-8_43-1
(2025) · Elsevier eBooks · doi:10.1016/b978-3-437-21835-4.00116-5
EMDR in Somatization and Persistent Physical Symptoms
Grant, M., & Tesarz, J. (2025) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780192898357.013.15
Prado, D. (2025) · Revista de Psicoterapia · doi:10.5944/rdp.v36i131.43900
SOMATINIŲ SIMPTOMŲ SUTRIKIMAS: NAUJA DIAGNOZĖ, SENI KLINIKINIAI IŠŠŪKIAI
Sergejev, K. (2025) · Health Sciences · doi:10.35988/sm-hs.2025.228
Adapt—Life on Remand: A Pilot Randomized Trial With Individuals in Pretrial Detention
Andrade, J., Gonçalves, R. A., & Rodrigues, A. D. C. (2025) · Journal of Clinical Psychology · doi:10.1002/jclp.70035 · Cited by 1
Kleinstäuber, M., Thomas, P., Witthöft, M., & Hiller, W. (2025) · Springer eBooks · doi:10.1007/978-3-662-69726-9_3
Self-citationSolving the mystery of emergency medicine: medically unexplained syndromes
Diószeghy, C., & Prentice, C. (2025) · Frontiers in Disaster and Emergency Medicine · doi:10.3389/femer.2025.1674150
Rovers, J. J. E., Braam, S., Scheffers, M., & Scharroo, J. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1661471
Feltz-Cornelis, C. M. V. D., & de Beurs, E. (2026) · Frontiers in Health Services · doi:10.3389/frhs.2026.1754286
yogev, M., & Gewirtz‐Meydan, A. (2026) · The Canadian Journal of Human Sexuality · doi:10.3138/cjhs-2025-0043
Nakamura, H., Taguchi, K., Katsushima, M., Okawa, S., Miyoshi, M., & Shimizu, E. (2026) · JMIR Formative Research · doi:10.2196/86698
“Among these, cognitive behavioral therapy (CBT) is the most commonly used psychosocial intervention for SSD [13,14].”
Lewis, H., Burton, L.-J., Morton, K., Wray, F., Kelley, R., Radford, K., & Guthrie, E. (2026) · Disability and Rehabilitation · doi:10.1080/09638288.2026.2679886
Metadata
- Authors
- van Dessel, N., den Boeft, M., van der Wouden, J. C., Kleinstäuber, M., Leone, S. S., Terluin, B., Numans, M. E., van der Horst, H. E., & van Marwijk, H.
- Affiliations
- EMGO Institute for Health and Care Research, VU University Medical Center; Department of General Practice and Elderly Care Medicine; Van der Boechorststraat 7, room D-550 Amsterdam Netherlands 1081 BT
- VU University Medical Center; Department of General Practice and Elderly Care Medicine, EMGO Institute for Health and Care Research; PO Box 7057 Amsterdam Netherlands 1007 MB
- Philipps University of Marburg (DE)
- Trimbos Institute (NL)
- Amsterdam Public Health (NL)
- Leiden University Medical Center (NL)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- Wiley
- Published
- 2014-11-01
- Volume
- 2014
- Issue
- 11
- Pages
- CD011142-CD011142
- ISSN
- 1361-6137 (ISSN-L)
- 1465-1858
- PMC
- PMC10984143
- OpenAlex
- W1603996513
- Cited by
- 302
- References
- 199
- Citations by year
- 2026: 9 · 2025: 22 · 2024: 19 · 2023: 24 · 2022: 18 · 2021: 35 · 2020: 23 · 2019: 41 · 2018: 32 · 2017: 36 · 2016: 23 · 2015: 18 · 2014: 1
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Digital Commons - USU (Utah State University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Keywords
- somatoform disorders, medically unexplained physical symptoms, non-pharmacological treatment, psychotherapy, cognitive behavioral therapy, mindfulness-based interventions, psychodynamic psychotherapy, integrative therapy, somatization disorder, undifferentiated somatoform disorder, pain disorders, treatment acceptability, somatic symptom severity, adults, third-wave CBT, behavior therapy
- MeSH terms
- Adult, Humans, Psychotherapy, Somatoform Disorders, Waiting Lists, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
