Epithelial‐to‐mesenchymal transition transcription factors in cancer‐associated fibroblasts

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

Desmoulière, A., Geinoz, A., Gabbiani, F., & Gabbiani, G. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.1.103 · Cited by 2,226 · see citing works

Molecular Genetics of Colorectal Cancer

Fearon, E. R. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130235 · Cited by 1,805 · see citing works

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

Calvo, F., Ege, N., Grande-Garcia, A., Hooper, S., Jenkins, R. P., Chaudhry, S. I., Harrington, K., Williamson, P., Moeendarbary, E., Charras, G., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2756 · Cited by 1,478 · see citing works

Collagen density promotes mammary tumor initiation and progression

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,364 · see citing works

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Conklin, M. W., Eickhoff, J. C., Riching, K. M., Pehlke, C. A., Eliceiri, K. W., Provenzano, P. P., Friedl, A., & Keely, P. J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.11.076 · Cited by 1,293 · see citing works

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

Calon, A., Espinet, E., Palomo-Ponce, S., Tauriello, D. V. F., Iglesias, M., Céspedes, M. V., Sevillano, M., Nadal, C., Jung, P., Zhang, X. H.-F., et al. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.08.013 · Cited by 1,060 · see citing works

Oncogenic roles of EMT-inducing transcription factors

Puisieux, A., Brabletz, T., & Caramel, J. (2014) · Nature Cell Biology · doi:10.1038/ncb2976 · Cited by 1,032 · see citing works

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

Wei, S. C., Fattet, L., Tsai, J. H., Guo, Y., Pai, V. H., Majeski, H. E., Chen, A. C., Sah, R. L., Taylor, S. S., Engler, A. J., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3157 · Cited by 934 · see citing works

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

Ansieau, S., Bastid, J., Doreau, A., Morel, A., Bouchet, B. P., Thomas, C., Fauvet, F., Puisieux, I., Doglioni, C., Piccinin, S., et al. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.06.005 · Cited by 713 · see citing works

The myofibroblast: Paradigm for a mechanically active cell

Hinz, B. (2009) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2009.09.020 · Cited by 695 · see citing works

CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS

Richards, K. E., Zeleniak, A. E., Fishel, M., Wu, J.-M., Littlepage, L. E., & Hill, R. (2016) · Oncogene · doi:10.1038/onc.2016.353 · Cited by 656 · see citing works

Mechanisms, mechanics and function of epithelial–mesenchymal transitions in early development

Shook, D. R., & Keller, R. E. (2003) · Mechanisms of Development · doi:10.1016/j.mod.2003.06.005 · Cited by 577 · see citing works

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

Zhang, P., Wei, Y., Wang, L., Debeb, B. G., Yuan, Y., Zhang, J., Yuan, J., Wang, M., Chen, D., Sun, Y., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3013 · Cited by 454 · see citing works

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes

Webber, J. P., Spary, L. K., Sanders, A. J., Chowdhury, R., Jiang, W. G., Steadman, R., Wymant, J. M., Jones, A. T., Kynaston, H., Mason, M. D., et al. (2014) · Oncogene · doi:10.1038/onc.2013.560 · Cited by 438 · see citing works

Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma

Wu, W.-S., Heinrichs, S., Xu, D., Garrison, S. P., Zambetti, G. P., Adams, J. M., & Look, A. T. (2005) · Cell · doi:10.1016/j.cell.2005.09.029 · Cited by 398 · see citing works

Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer

Malik, R., Lelkes, P. I., & Cukierman, E. (2015) · Trends in biotechnology · doi:10.1016/j.tibtech.2015.01.004 · Cited by 349 · see citing works

TGF-beta in CAF-mediated tumor growth and metastasis

Calon, A., Tauriello, D. V. F., & Batlle, E. (2014) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2013.12.008 · Cited by 342 · see citing works

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

Lehmann, W., Mossmann, D., Kleemann, J., Mock, K., Meisinger, C., Brummer, T., Herr, R., Brabletz, S., Stemmler, M. P., & Brabletz, T. (2016) · Nature Communications · doi:10.1038/ncomms10498 · Cited by 305 · see citing works

Fibroblast activation in cancer: when seed fertilizes soil

Kužet, S.-E., & Gaggioli, C. (2016) · Cell and Tissue Research · doi:10.1007/s00441-016-2467-x · Cited by 286 · see citing works

High levels of transforming growth factor beta 1 in patients with colorectal cancer: Association with disease progression

Tsushima, H., Kawata, S., Tamura, S., Ito, N., Shirai, Y., Kiso, S., Imai, Y., Shimomukai, H., Nomura, Y., Matsuda, Y., et al. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8566583 · Cited by 282 · see citing works

The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity

Nieto, M. A., & Cano, A. (2012) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2012.05.003 · Cited by 263 · see citing works

Snail and Slug Play Distinct Roles during Breast Carcinoma Progression

Côme, C., Magnino, F., Bibeau, F., Barbara, P. D. S., Becker, K., Theillet, C. G., & Savagner, P. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-0478 · Cited by 261 · see citing works

The wound healing, chronic fibrosis, and cancer progression triad

Rybinski, B., Franco‐Barraza, J., & Cukierman, E. (2014) · Physiological Genomics · doi:10.1152/physiolgenomics.00158.2013 · Cited by 255 · see citing works

Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro.

Steiner, M. S., & Barrack, E. R. (1992) · Molecular Endocrinology · doi:10.1210/mend.6.1.1738367 · Cited by 239 · see citing works

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1

Ota, I., Li, X.-Y., Hu, Y., & Weiss, S. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910962106 · Cited by 224 · see citing works

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

Procopio, M.-G., Laszlo, C., Al Labban, D., Kim, D. E., Bordignon, P., Jo, S.-H., Goruppi, S., Menietti, E., Ostano, P., Ala, U., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3228 · Cited by 223 · see citing works

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming

Liu, X., Sun, H., Qi, J. Y., Wang, L., He, S., Liu, J., Feng, C., Chen, C., Li, W., Guo, Y., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2765 · Cited by 220 · see citing works

Expression of Snail protein in tumor–stroma interface

Francı́, C., Takkunen, M., Dave, N., Alameda, F., Gómez, S., Rodríguez, R., Escrivà, M., Montserrat-Sentís, B., Baró, T., Garrido, M., et al. (2006) · Oncogene · doi:10.1038/sj.onc.1209519 · Cited by 219 · see citing works

ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis

Peng, D. H., Ungewiss, C., Tong, P., Byers, L. A., Wang, J., Canales, J. R., Villalobos, P. A., Uraoka, N., Mino, B., Behrens, C., et al. (2016) · Oncogene · doi:10.1038/onc.2016.358 · Cited by 211 · see citing works

TWIST Family of Basic Helix-Loop-Helix Transcription Factors Mediate Human Mesenchymal Stem Cell Growth and Commitment

Isenmann, S., Arthur, A., Zannettino, A. C. W., Turner, J. L., Shi, S., Glackin, C. A., & Gronthos, S. (2009) · Stem Cells · doi:10.1002/stem.181 · Cited by 209 · see citing works

Carcinoma‐associated fibroblasts: Non‐neoplastic tumour‐promoting mesenchymal cells

Polanska, U. M., & Orimo, A. (2013) · Journal of Cellular Physiology · doi:10.1002/jcp.24347 · Cited by 208 · see citing works

Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation

Tang, Y., Feinberg, T. Y., Keller, E. T., Li, X.-Y., & Weiss, S. J. (2016) · Nature Cell Biology · doi:10.1038/ncb3394 · Cited by 208 · see citing works

Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis

Escrivà, M., Peiró, S., Herranz, N., Villagrasa, P., Dave, N., Montserrat-Sentís, B., Murray, S. A., Francı́, C., Gridley, T., Virtanen, I., et al. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.02061-07 · Cited by 190 · see citing works

Expression of M‐twist during postimplantation development of the mouse

Füchtbauer, E. (1995) · Developmental Dynamics · doi:10.1002/aja.1002040309 · Cited by 178 · see citing works

Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature

Herrera, M., Islam, A. B. M. M. K., Herrera, A., Martín, P., García‐Barberán, V., Silva, J., Garcia, J. M., Salas, C., Casal, J. I., de Herreros, A. G., et al. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-0694 · Cited by 177 · see citing works

TWISTing an embryonic transcription factor into an oncoprotein

Ansieau, S., Morel, A.-P., Hinkal, G. W., Bastid, J., & Puisieux, A. (2010) · Oncogene · doi:10.1038/onc.2010.92 · Cited by 169 · see citing works

Epidermal Growth Factor Receptor and Mutant p53 Expand an Esophageal Cellular Subpopulation Capable of Epithelial-to-Mesenchymal Transition through ZEB Transcription Factors

Ohashi, S., Natsuizaka, M., Wong, G. S., Michaylira, C. Z., Grugan, K. D., Stairs, D. B., Kalabis, J., Vega, M. E., Kalman, R. A., Nakagawa, M., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4614 · Cited by 164 · see citing works

Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion

Zhang, H., von Gise, A., Liu, Q., Hu, T., Tian, X., He, L., Pu, W., Huang, X., He, L., Cai, C., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.554584 · Cited by 162 · see citing works

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

Rowe, R. G., Li, X.-Y., Hu, Y., Saunders, T. L., Virtanen, I., de Herreros, A. G., Becker, K., Ingvarsen, S., Engelholm, L. H., Bommer, G. T., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200810113 · Cited by 159 · see citing works

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

Weiss, M. B., Abel, E. V., Mayberry, M. M., Basile, K. J., Berger, A. C., & Aplin, A. E. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-1033 · Cited by 155 · see citing works

Twist1 Is a Key Regulator of Cancer-Associated Fibroblasts

Lee, K.-W., Yeo, S.-Y., Sung, C. O., & Kim, S. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-0350 · Cited by 140 · see citing works

Arecoline‐induced myofibroblast transdifferentiation from human buccal mucosal fibroblasts is mediated by ZEB 1

Chang, Y., Tsai, C., Lai, Y., Yu, C., Chi, W., Li, J. J., & Chang, W. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12219 · Cited by 137 · see citing works

Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer

Ni, T., Li, X.-Y., Lu, N., An, T., Liu, Z., Fu, R., Lv, W.-C., Zhang, Y.-W., Xu, X.-J., Rowe, R. G., et al. (2016) · Nature Cell Biology · doi:10.1038/ncb3425 · Cited by 129 · see citing works

F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check

Diaz, V. M., & de Herreros, A. G. (2015) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2015.10.003 · Cited by 126 · see citing works

Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis

Stanisavljević, J., Loubat‐Casanovas, J., Herrera, M., Luque, T., Peña, R., Lluch, A. M., Albanell, J., Bonilla, F., Rovira, A., Peña, C., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-1903 · Cited by 123 · see citing works

Cloning of the human twist gene: Its expression is retained in adult mesodermally-derived tissues

Wang, S. M., Coljee, V. W., Pignolo, R. J., Rotenberg, M. O., Cristofalo, V. J., & Sierra, F. (1997) · Gene · doi:10.1016/s0378-1119(96)00727-5 · Cited by 116 · see citing works

Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1

Zhao, X., Sun, T., Che, N., Sun, D., Zhao, N., Dong, X.-Y., Gu, Q., Yao, Z., & Sun, B. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01052.x · Cited by 115 · see citing works

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

Vellinga, T. T., den Uil, S., Rinkes, I. H. B., Marvin, D., Ponsioen, B., Alvarez-Varela, A., Fatrai, S., Scheele, C., Zwijnenburg, D. A., Snippert, H., et al. (2016) · Oncogene · doi:10.1038/onc.2016.60 · Cited by 115 · see citing works

A “Twist box” Code of p53 Inactivation: Twist box:p53 Interaction Promotes p53 Degradation

Piccinin, S., Tonin, E., Sessa, S., Demontis, S., Rossi, S., Pecciarini, L., Zanatta, L., Pivetta, F., Grizzo, A., Sonego, M., et al. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.08.003 · Cited by 112 · see citing works

Snail1 Protein in the Stroma as a New Putative Prognosis Marker for Colon Tumours

Francı́, C., Gallén, M., Alameda, F., Baró, T., Iglesias, M., Virtanen, I., & de Herreros, A. G. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005595 · Cited by 106 · see citing works

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer

Selth, L. A., Das, R., Townley, S. L., Coutinho, I., Hanson, A. R., Centenera, M. M., Stylianou, N., Sweeney, K. G., Soekmadji, C., Jovanovic, L., et al. (2016) · Oncogene · doi:10.1038/onc.2016.185 · Cited by 106 · see citing works

Regulation of the protein stability of EMT transcription factors

Diaz, V. M., Viñas-Castells, R., & de Herreros, A. G. (2014) · Cell Adhesion & Migration · doi:10.4161/19336918.2014.969998 · Cited by 103 · see citing works

Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro

Steiner, M. S. (1992) · Molecular Endocrinology · doi:10.1210/me.6.1.15 · Cited by 95 · see citing works

Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer

Bronsert, P., Kohler, I., Timme, S., Kiefer, S., Werner, M., Schilling, O., Vashist, Y. K., Makowiec, F., Brabletz, T., Hopt, U. T., et al. (2014) · Surgery · doi:10.1016/j.surg.2014.02.018 · Cited by 93 · see citing works

Mesenchymal CD44 Expression Contributes to the Acquisition of an Activated Fibroblast Phenotype via TWIST Activation in the Tumor Microenvironment

Spaeth, E. L., LaBaff, A. M., Toole, B. P., Klopp, A. H., Andreeff, M., & Marini, F. C. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-0087 · Cited by 90 · see citing works

Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients

Romàn-Pèrez, E., Casbas-Hernández, P., Pirone, J. R., Rein, J., Carey, L., Lubet, R. A., Mani, S. A., Amos, K. D., & Troester, M. A. (2012) · Breast Cancer Research · doi:10.1186/bcr3152 · Cited by 87 · see citing works

Twist1 Is Up-Regulated in Gastric Cancer-Associated Fibroblasts with Poor Clinical Outcomes

Sung, C. O., Lee, K., Han, S., & Kim, S. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.06.032 · Cited by 79 · see citing works

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI)

García‐Palmero, I., Torres, S., Bartolomé, R. A., Peláez‐García, A., Larriba, M. J., López-Lucendo, M. F., Peña, C., Escudero-Paniagua, B., Múñoz, A., & Casal, J. I. (2016) · Oncogene · doi:10.1038/onc.2016.57 · Cited by 79 · see citing works

Dorso-ventral and rostro-caudal sequential expression of M-twist in the postimplantation murine embryo

Stoetzel, C., Weber, B., Bourgeois, P., Bolcato‐Bellemin, A., & Perrin‐Schmitt, F. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(95)00369-x · Cited by 78 · see citing works

Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of cancer-associated fibroblasts

Zhang, K., Grither, W. R., Hove, S. V., Biswas, H., Ponik, S. M., Eliceiri, K. W., Keely, P. J., & Longmore, G. D. (2016) · Journal of Cell Science · doi:10.1242/jcs.180539 · Cited by 78 · see citing works

Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis

Alba‐Castellón, L., Olivera‐Salguero, R., Mestre‐Farrera, A., Peña, R., Herrera, M., Bonilla, F., Casal, J. I., Baulida, J., Peña, C., & de Herreros, A. G. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-0176 · Cited by 78 · see citing works

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer

Galván, J. A., Stüssi‐Helbling, M., Koelzer, V. H., Tschan, M. P., Berger, M. D., Hädrich, M., Schnüriger, B., Karamitopoulou, E., Dawson, H., Inderbitzin, D., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.2716 · Cited by 72 · see citing works

Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells

Batlle, R., Alba‐Castellón, L., Loubat‐Casanovas, J., Armenteros-Monterroso, E., Francı́, C., Stanisavljević, J., Banderas, R., Martín‐Caballero, J., Bonilla, F., Baulida, J., et al. (2012) · Oncogene · doi:10.1038/onc.2012.342 · Cited by 71 · see citing works

Snail1-driven plasticity of epithelial and mesenchymal cells sustains cancer malignancy

Baulida, J., & de Herreros, A. G. (2015) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2015.05.005 · Cited by 64 · see citing works

EMT or EMT-Promoting Transcription Factors, Where to Focus the Light?

Ansieau, S., Collin, G., & Hill, L. (2014) · Frontiers in Oncology · doi:10.3389/fonc.2014.00353 · Cited by 62 · see citing works

Inhibition of TWIST1 Leads to Activation of Oncogene-Induced Senescence in Oncogene-Driven Non–Small Cell Lung Cancer

Burns, T. F., Dobromilskaya, I., Murphy, S. C., Gajula, R. P., Thiyagarajan, S., Chatley, S. N. H., Aziz, K., Cho, Y., Tran, P. T., & Rudin, C. M. (2013) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-12-0456 · Cited by 61 · see citing works

Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression

Jouppila‐Mättö, A., Närkiö‐Mäkelä, M., Soini, Y., Pukkila, M. J., Sironen, R. K., Tuhkanen, H. E., Mannermaa, A., & Kosma, V. (2011) · BMC Cancer · doi:10.1186/1471-2407-11-350 · Cited by 55 · see citing works

Aberrant miR-21 and miR-200b expression and its pro-fibrotic potential in hypertrophic scars

Zhou, R., Zhang, Q., Zhang, Y., Fu, S., & Wang, C. (2015) · Experimental Cell Research · doi:10.1016/j.yexcr.2015.10.018 · Cited by 50 · see citing works

The Ski/Zeb2/Meox2 pathway provides a novel mechanism for regulation of the cardiac myofibroblast phenotype

Cunnington, R. H., Northcott, J. M., Ghavami, S., Bathe, K. L., Jahan, F., Kavosh, M., Davies, J., Wigle, J. T., & Dixon, I. (2013) · Journal of Cell Science · doi:10.1242/jcs.126722 · Cited by 50 · see citing works

Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis

Palumbo‐Zerr, K., Soare, A., Zerr, P., Liebl, A., Mancuso, R., Tomčík, M., Šumová, B., Dees, C., Chen, C., Wohlfahrt, T., et al. (2016) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2015-208470 · Cited by 48 · see citing works

A Possible Inflammatory Role of Twist1 in Human White Adipocytes

Pettersson, A., Laurencikiene, J., Mejhert, N., Näslund, E. B., Bouloumié, A., Dahlman, I. A., Arner, P., & Rydén, M. (2009) · Diabetes · doi:10.2337/db09-0997 · Cited by 44 · see citing works

Protumorigenic effects of Snail‐expression fibroblasts on colon cancer cells

Herrera, A., Herrera, M., Alba‐Castellón, L., Silva, J., García‐Barberán, V., Loubat‐Casanovas, J., Álvarez‐Cienfuegos, A., García, J. M., Rodríguez, R., Gil, B., et al. (2013) · International Journal of Cancer · doi:10.1002/ijc.28613 · Cited by 42 · see citing works

Up-regulation of stromal cell-derived factor-1α and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma

Taki, M., Higashikawa, K., Yoneda, S., Ono, S., Shigeishi, H., Nagayama, M., & Kamata, N. (2008) · Oncology Reports · doi:10.3892/or.19.4.993 · Cited by 39 · see citing works

Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury

Biswas, H., & Longmore, G. D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162636 · Cited by 29 · see citing works

Snail1 Expression Is Required for Sarcomagenesis

Alba‐Castellón, L., Batlle, R., Francı́, C., Fernández‐Aceñero, M. J., Mazzolini, R., Peña, R., Loubat‐Casanovas, J., Alameda, F., Rodríguez, R., Curto, J., et al. (2014) · Neoplasia · doi:10.1016/j.neo.2014.05.002 · Cited by 28 · see citing works

Immunohistochemical expression of epithelial and stromal immunomodulatory signalling molecules is a prognostic indicator in breast cancer

Richardsen, E. H., Uglehus, R. D., Johnsen, S. H., & Busund, L. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-110 · Cited by 26 · see citing works

Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury

Scarpa, M., Grillo, A. R., Brun, P., Macchi, V., Stefani, A., Signori, S., Buda, A., Fabris, P., Giordani, M. T., De, R., et al. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00141.2010 · Cited by 26 · see citing works

Snail1 is involved in de novo cardiac fibrosis after myocardial infarction in mice

Liu, Y., Du, J., Jin, Z., Weng, M., Li, X., Di, P., Gao, L., Deng, S., Xia, S., & She, Q. (2012) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gms085 · Cited by 21 · see citing works

Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders

Goyal, A., Linskey, K. R., Kay, J., Duncan, L. M., & Nazarian, R. M. (2016) · American Journal of Clinical Pathology · doi:10.1093/ajcp/aqw192 · Cited by 15 · see citing works

Transcription factor snail1 expression and poor survival in pharyngeal squamous cell carcinoma.

Jouppila‐Mättö, A., Tuhkanen, H. E., Soini, Y., Pukkila, M. J., Närkiö‐Mäkelä, M., Sironen, R. K., Virtanen, I., Mannermaa, A., & Kosma, V. (2011) · PubMed · doi:10.14670/hh-26.443 · Cited by 14 · see citing works

SIP1 predicts progression and poor prognosis in pharyngeal squamous cell carcinoma.

Jouppila‐Mättö, A., Mannermaa, A., Sironen, R. K., Kosma, V., Soini, Y., & Pukkila, M. J. (2015) · PubMed · doi:10.14670/hh-30.569 · Cited by 5 · see citing works

TGFβ biology in cancer progression and immunotherapy

Derynck, R., Turley, S. J., & Akhurst, R. J. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-0403-1 · Cited by 944 · see citing works

Controversies around epithelial–mesenchymal plasticity in cancer metastasis

Williams, E. D., Gao, D., Redfern, A. D., & Thompson, E. W. (2019) · Nature reviews. Cancer · doi:10.1038/s41568-019-0213-x · Cited by 451 · see citing works

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

Caja, L., Dituri, F., Mancarella, S., Caballero‐Díaz, D., Moustakas, A., Giannelli, G., & Fabregat, I. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051294 · Cited by 353 · see citing works

Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

Phan, T. H. G., Paliogiannis, P., Nasrallah, G. K., Giordo, R., Eid, A. H., Fois, A. G., Zinellu, A., Mangoni, A. A., & Pintus, G. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03693-7 · Cited by 355 · see citing works

Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology

Rout-Pitt, N., Farrow, N., Parsons, D., & Donnelley, M. (2018) · Respiratory Research · doi:10.1186/s12931-018-0834-8 · Cited by 275 · see citing works

Biophysics of tumor microenvironment and cancer metastasis – a mini review

Emon, B., Bauer, J., Jain, Y., Jung, B., & Saif, T. (2018) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2018.07.003 · Cited by 245 · see citing works

Cancer-associated fibroblasts and resistance to anticancer therapies: status, mechanisms, and countermeasures

Feng, B., Wu, J., Shen, B., Jiang, F., & Feng, J. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02599-7 · Cited by 210 · see citing works

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

Djurec, M., Graña‐Castro, O., Lee, A., Troulé, K., Espinet, E., Cabras, L., Navas, C., Blasco, M. T., Martín-Díaz, L., Burdiel, M., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1717802115 · Cited by 178 · see citing works

ENO1 Promotes Lung Cancer Metastasis via HGFR and WNT Signaling–Driven Epithelial-to-Mesenchymal Transition

Li, H., Ke, F.-Y., Lin, C.-C. J., Lu, M.-Y., Kuo, Y.-H., Wang, Y., Liang, K.-H., Lin, S.-C., Chang, Y.-H., Chen, H., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-3543 · Cited by 172 · see citing works

Epithelial–mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?

van Staalduinen, J., Baker, D., ten Dijke, P., & van Dam, H. (2018) · Oncogene · doi:10.1038/s41388-018-0378-x · Cited by 158 · see citing works

The transformation of cancer-associated fibroblasts: Current perspectives on the role of TGF-β in CAF mediated tumor progression and therapeutic resistance

Jena, B. C., Sarkar, S., Rout, L., & Mandal, M. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.08.002 · Cited by 137 · see citing works

Emerging Nano Drug Delivery Systems Targeting Cancer-Associated Fibroblasts for Improved Antitumor Effect and Tumor Drug Penetration

Guo, J. X., Zeng, H., & Chen, Y. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00014 · Cited by 90 · see citing works

Transcription factors in fibroblast plasticity and CAF heterogeneity

Melchionna, R., Trono, P., Carlo, A. D., Modugno, F. D., & Nisticò, P. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02934-4 · Cited by 87 · see citing works

Clinical significance of tumor-stroma ratio in head and neck cancer: a systematic review and meta-analysis

Almangush, A., Alabi, R. O., Troiano, G., Coletta, R. D., Salo, T. A., Pirinen, M., Mäkitie, A. A., & Leivo, I. V. V. (2021) · BMC Cancer · doi:10.1186/s12885-021-08222-8 · Cited by 79 · see citing works

Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progression

Jena, B. C., Das, C. K., Bharadwaj, D., & Mandal, M. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188416 · Cited by 70 · see citing works

Staphylococcal mastitis in dairy cows

Dego, O. K., & Vidlund, J. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1356259 · Cited by 78 · see citing works

Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment

Szabó, P. M., Vajdi, A., Kumar, N., Tolstorukov, M. Y., Chen, B. J., Edwards, R. H., Ligon, K. L., Chasalow, S. D., Chow, K.-H., Shetty, A., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-28480-9 · Cited by 65 · see citing works

Phenotypic heterogeneity, stability and plasticity in tumor‐promoting carcinoma‐associated fibroblasts

Mezawa, Y., & Orimo, A. (2021) · FEBS Journal · doi:10.1111/febs.15851 · Cited by 59 · see citing works

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles

Bhome, R., Emaduddin, M., James, V. H., House, L. M., Thirdborough, S. M., Mellone, M., Tulkens, J., Primrose, J. N., Thomas, G. J., Wever, O. D., et al. (2022) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12226 · Cited by 50 · see citing works

Cancer-associated fibroblasts: protagonists of the tumor microenvironment in gastric cancer

Ozmen, E., Demir, T. D., & Özcan, G. (2024) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2024.1340124 · Cited by 49 · see citing works

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

Banales, J. M., Marin, J. J. G., Lamarca, A., Rodrigues, P. M., Khan, S. A., Roberts, L. R., Cardinale, V., Carpino, G., Andersen, J. B., Braconi, C., et al. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-0310-z · Cited by 2,411 · see citing works

Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer

Li, Z., Zhang, J., Zhou, J., Lu, L., Wang, H., Zhang, G., Wan, G., Cai, S., & Du, J. (2019) · Cells · doi:10.3390/cells8060538 · Cited by 46 · see citing works

Mechanoregulation of Cancer-Associated Fibroblast Phenotype in Three-Dimensional Interpenetrating Hydrogel Networks

Cao, H., Lee, M. K. H., Yang, H., Sze, S. K., Tan, N. S., & Tay, C. Y. (2018) · Langmuir · doi:10.1021/acs.langmuir.8b02649 · Cited by 44 · see citing works

Quantitative proteomic profiling of primary cancer-associated fibroblasts in oesophageal adenocarcinoma

Manousopoulou, A., Hayden, A. L., Mellone, M., Garay‐Baquero, D. J., White, C., Noble, F., López, M. E. P., Thomas, G. J., Underwood, T., & Garbis, S. D. (2018) · British Journal of Cancer · doi:10.1038/s41416-018-0042-9 · Cited by 39 · see citing works

In silico identification of MAPK14-related lncRNAs and assessment of their expression in breast cancer samples

Dashti, S., Taherian‐Esfahani, Z., Kholghi‐Oskooei, V., Noroozi, R., Arsang-Jang, S., Ghafouri‐Fard, S., & Taheri, M. N. (2020) · Scientific Reports · doi:10.1038/s41598-020-65421-2 · Cited by 34 · see citing works

Role of CC Chemokines Subfamily in the Platinum Drugs Resistance Promotion in Cancer

Reyes, M. E., la Fuente, M. D., Hermoso, M. A., Ili, C., & Brebi, P. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00901 · Cited by 30 · see citing works

A novel epithelial–mesenchymal transition gene signature for the immune status and prognosis of hepatocellular carcinoma

Shi, Y., Wang, J., Huang, G. C., Zhu, J. W., Jian, H., Xia, G., Wei, Q., Li, Y., & Yu, H. (2022) · Hepatology International · doi:10.1007/s12072-022-10354-3 · Cited by 30 · see citing works

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma

Jiang, Z., Zhai, X., Shi, B., Luo, D., & Jin, B. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s187389 · Cited by 28 · see citing works

Cancer-Associated Stromal Fibroblast-Derived Transcriptomes Predict Poor Clinical Outcomes and Immunosuppression in Colon Cancer

Wang, J., Akter, R., Shahriar, M. F., & Uddin, M. N. (2022) · Pathology & Oncology Research · doi:10.3389/pore.2022.1610350 · Cited by 27 · see citing works

Abrogation of myofibroblast activities in metastasis and fibrosis by methyltransferase inhibition

Sala, L., Franco‐Valls, H., Stanisavljević, J., Curto, J., Vergés, J., Peña, R., Duch, P., Alcaraz, J., de Herreros, A. G., & Baulida, J. (2019) · International Journal of Cancer · doi:10.1002/ijc.32376 · Cited by 27 · see citing works

Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells

Acuña, R. A., Varas‐Godoy, M., Herrera-Sepulveda, D., & Retamal, M. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212604 · Cited by 23 · see citing works

Sigma-1 Receptor Alleviates Airway Inflammation and Airway Remodeling Through AMPK/CXCR4 Signal Pathway

Jiang, T., Zhao, D., Zheng, Z., & Li, Z. (2022) · Inflammation · doi:10.1007/s10753-022-01621-4 · Cited by 22 · see citing works

The role of transcription factors in the crosstalk between cancer-associated fibroblasts and tumor cells

Zhang, X., Zhang, M., Sun, H., Wang, X., Wang, X., Sheng, W., & Xu, M. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.01.033 · Cited by 22 · see citing works

Nano-Drug Delivery Systems Targeting CAFs: A Promising Treatment for Pancreatic Cancer

Wang, M., Xue, W., Yuan, H., Wang, Z., & Yu, L. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s451151 · Cited by 23 · see citing works

Single-cell deconvolution reveals high lineage- and location-dependent heterogeneity in mesenchymal multivisceral stage 4 colorectal cancer

Berlin, C., Mauerer, B., Cauchy, P., Lünstedt, J., Sankowski, R., Marx, L., Feuerstein, R., Schaefer, L., Greten, F. R., Pesic, M. H., et al. (2023) · Journal of Clinical Investigation · doi:10.1172/jci169576 · Cited by 19 · see citing works

Charactering tumor microenvironment reveals stromal‐related transcription factors promote tumor carcinogenesis in gastric cancer

Liu, H., Ni, S., Wang, H., Zhang, Q., & Weng, W. (2020) · Cancer Medicine · doi:10.1002/cam4.3133 · Cited by 19 · see citing works

Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma

Zhai, X., Wang, W., Ma, Y., Zeng, Y., Dou, D., Fan, H., Song, J., Yu, X., Xin, D., Du, G., et al. (2020) · Aging · doi:10.18632/aging.103964 · Cited by 19 · see citing works

Unraveling the role of cancer-associated fibroblasts in colorectal cancer

Cui, J., Ma, J., Gao, X., Sheng, Z.-M., Pan, Z., Shi, L., & Zhang, B. (2024) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v16.i12.4565 · Cited by 18 · see citing works

Helicobacter pylori–activated fibroblasts as a silent partner in gastric cancer development

Krzysiek-Mączka, G., Brzozowski, T., & Ptak‐Belowska, A. (2023) · Cancer and Metastasis Reviews · doi:10.1007/s10555-023-10122-1 · Cited by 20 · see citing works

Regulation of fibroblast-like synoviocyte transformation by transcription factors in arthritic diseases

Bhattaram, P., & Jones, K. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.03.018 · Cited by 18 · see citing works

The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment

Gulia, S., Chandra, P., & Das, A. (2023) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-023-01179-4 · Cited by 16 · see citing works

Modeling the epithelial-mesenchymal transition process in a 3D organotypic cervical neoplasia

Gregorio, V. D., Rocca, A. L., Urciuolo, F., Annunziata, C., Tornesello, M. L., Buonaguro, F. M., Netti, P. A., & Imparato, G. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.09.006 · Cited by 16 · see citing works

Progress in Expression Pattern and Molecular Regulation Mechanism of LncRNA in Bovine Mastitis

Li, J., Wang, J., Luoreng, Z., Wang, X., Wei, D., Yang, J., Hu, Q., & Ma, Y. (2022) · Animals · doi:10.3390/ani12091059 · Cited by 16 · see citing works

Tumor Stroma as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

Lee, D. U., Han, B. S., Jung, K. H., & Hong, S. (2024) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2024.029 · Cited by 15 · see citing works

GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism

Shi, Q., Xu, R., Song, G., Hao, L., Xue, D., He, X., & Xia, Y. (2019) · Cancer Gene Therapy · doi:10.1038/s41417-019-0146-2 · Cited by 15 · see citing works

The Areca Nut and Oral Submucosal Fibrosis: A Narrative Review

Kazemi, K., Fadl, A., Sperandio, F. F., & Leask, A. (2025) · Dentistry Journal · doi:10.3390/dj13080364 · Cited by 13 · see citing works

Cancer‑associated fibroblasts as cellular vehicles in endometrial cancer cell migration

Voon, Y., Omar, I. S., Wu, M., Said, N. A. B. M., & Chung, I. (2021) · Oncology Letters · doi:10.3892/ol.2021.13121 · Cited by 13 · see citing works

Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · BMC Medicine · doi:10.1186/s12916-022-02489-9 · Cited by 13 · see citing works

GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition

Li, M., Wang, X., Chen, X., Hong, J., Ye, D., & Song, D. E. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166925 · Cited by 13 · see citing works

Protein expression patterns in cancer-associated fibroblasts and cells undergoing the epithelial-mesenchymal transition in ovarian cancers

Fukagawa, D., Sugai, T., Osakabe, M., Suga, Y., Nagasawa, T., Itamochi, H., & Sugiyama, T. (2018) · Oncotarget · doi:10.18632/oncotarget.25518 · Cited by 13 · see citing works

Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin

Franco‐Valls, H., Tusquets-Uxó, E., Sala, L., Val-Casals, M., Peña, R., Iaconcig, A., Villarino, Á., Jiménez-Arriola, M., Massó, P., Trincado, J. L., et al. (2023) · Breast Cancer Research · doi:10.1186/s13058-023-01736-y · Cited by 12 · see citing works

A proteomics outlook towards the elucidation of epithelial–mesenchymal transition molecular events

Silvestrini, V. C., Lanfredi, G. P., Masson, A. P., Poersch, A., Ferreira, G. A., Thomé, C. H., & Faça, V. M. (2019) · Molecular Omics · doi:10.1039/c9mo00095j · Cited by 12 · see citing works

From darkness to light: Targeting CAFs as a new potential strategy for cancer treatment

Tian, H., Wang, W., Liang, S., Ding, J., & Hua, D. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113482 · Cited by 9 · see citing works

MSI2 knockdown represses extrahepatic cholangiocarcinoma growth and invasion by inhibiting epithelial–mesenchymal transition

Hu, F., Liu, C., Xie, F., Lin, X., Yang, J. H., Wang, C., & Huang, Q. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s170739 · Cited by 9 · see citing works

Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells

Handa, H., Hashimoto, A., Hashimoto, S., Sugino, H., Oikawa, T., & Sabe, H. (2018) · Cell Communication and Signaling · doi:10.1186/s12964-018-0302-6 · Cited by 9 · see citing works

Geneticin ameliorates pulmonary fibrosis by attenuating the TGF-β/Smad via modulating AMPK/SIRT1 signaling

Tirunavalli, S. K., & Andugulapati, S. B. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122626 · Cited by 7 · see citing works

ZEB1 recruits BRG1 to regulate airway remodelling epithelial‐to‐mesenchymal transition in asthma

Wang, T., Peng, B., Luo, T., Tian, D., Zhao, Z., Fu, Z., & Li, Q. (2022) · Experimental Physiology · doi:10.1113/ep090212 · Cited by 7 · see citing works

Targeting ROR1 inhibits epithelial to mesenchymal transition in human lung adenocarcinoma via mTOR signaling pathway.

Long, M., Wang, H.-L., Luo, Y.-B., & Yang, J. (2018) · Europe PMC (PubMed Central) · Cited by 7 · see citing works

Correction: GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism

Shi, Q., Xu, R., Song, G., Hao, L., Xue, D., He, X., & Xia, Y. (2020) · Cancer Gene Therapy · doi:10.1038/s41417-020-00229-w · Cited by 7 · see citing works

Current perspectives and trends in colorectal cancer and cancer-associated fibroblasts: a review and bibliometric analysis

Qian, C., Ren, L., Zhu, S., Chen, F., Shen, H., Hu, X., & Chen, G. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1618742 · Cited by 6 · see citing works

Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

Mohamed, I. S. E., Васильевна, С. А., Markov, O. V., Markov, A. V., Savin, I. A., Аркадьевна, З. М., & Mironova, N. L. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14061173 · Cited by 5 · see citing works

Epithelial to Mesenchymal Transition

Dalton, A. C., & Howe, P. H. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00005-0 · Cited by 5 · see citing works

KBTBD8/RRP15 as a potential novel therapeutic target associates with lenvatinib-inhibited progression in hepatocellular carcinoma both in vitro and in vivo

Zhao, S., Wang, X., Wu, R. T., Wang, F., Tang, X., Chen, J., Jiang, R., Kang, W., Xu, G., Wang, L., et al. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.12.017 · Cited by 4 · see citing works

USP27X, a new player on EMT and fibroblast activation

Diaz, V. M. (2018) · Oncotarget · doi:10.18632/oncotarget.26410 · Cited by 4 · see citing works

Modeling cancer-associated fibroblast plasticity and breast cancer interactions using patient-derived scaffolds

Ruiz‐Martínez, S., Gustafsson, A., Johansson, E., Garré, E., Helou, K., Ståhlberg, A., & Landberg, G. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118952 · Cited by 3 · see citing works

Single‐Cell and Spatial Transcriptomics Explore Purine Metabolism–Related Prognostic Risk Model and Tumor Immune Microenvironment Modulation in Ovarian Cancer

Liu, Y., Geng, R., Zhao, S., Yang, J., Liu, J., Zheng, Y., & Tang, W. (2025) · Human Mutation · doi:10.1155/humu/5530325 · Cited by 3 · see citing works

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation

Ouali, B. E. F., Liu, T., Lu, C.-Y., Cheng, P.-Y., Huang, C., Li, C.-C., Chiang, Y., & Wang, H. (2020) · BMC Research Notes · doi:10.1186/s13104-020-05152-9 · Cited by 3 · see citing works

RV-specific Targeting of Snai1 Rescues Pulmonary Hypertension-induced Right Ventricular Failure by Inhibiting EndMT and Fibrosis via LOXL2 Mediated MechanismPreprint

Banerjee, S., Clark, V. R., Hong, J. S., Martineau, S., Fishbein, G. A., Bonnet, S. B., Provencher, S., Bonnet, S., & Umar, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.30.591766 · Cited by 3 · see citing works

El papel del microambiente tumoral y los fibroblastos asociados a cáncer en el desarrollo y la progresión del cáncer de mama

Ramírez-Farías, C., González‐Blas, D., & Quintanar‐Stephano, A. (2021) · Revista de Senología y Patología Mamaria · doi:10.1016/j.senol.2021.08.003 · Cited by 2 · see citing works

Extracellular Vesicles from Lung Adenocarcinoma Cells Induce Activation of Different Cancer-Associated Fibroblast Subtypes

Trejo, J., Towle, R. M., Farnsworth, D., Sarafan, M., Lockwood, W. W., & Garnis, C. (2024) · Biomedicines · doi:10.3390/biomedicines12112523 · Cited by 2 · see citing works

Demethyleneberberine ameliorates pulmonary fibrosis by inhibiting the NLRP3 inflammasome and the epithelial–mesenchymal transition

Wang, X., Wu, X., Zhou, L., Lin, Y., Tang, Z., Chen, C., Wang, B., & Lin, Y.-T. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115003 · Cited by 2 · see citing works

Data from ENO1 Promotes Lung Cancer Metastasis via HGFR and WNT Signaling–Driven Epithelial-to-Mesenchymal Transition

Li, H., Ke, F.-Y., Lin, C.-C., Lu, M.-Y., Kuo, Y.-H., Wang, Y., Liang, K.-H., Lin, S.-C., Chang, Y.-H., Chen, H., et al. (2023) · doi:10.1158/0008-5472.c.6513010.v1 · Cited by 1 · see citing works

Faculty Opinions recommendation of Cholangiocarcinoma 2020: the next horizon in mechanisms and management.

Borad, M. J. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.738244264.793579671

Data from ENO1 Promotes Lung Cancer Metastasis via HGFR and WNT Signaling–Driven Epithelial-to-Mesenchymal Transition

Li, H., Ke, F.-Y., Lin, C.-C., Lu, M.-Y., Kuo, Y.-H., Wang, Y., Liang, K.-H., Lin, S.-C., Chang, Y.-H., Chen, H., et al. (2023) · doi:10.1158/0008-5472.c.6513010

Additional file 4 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069666

Additional file 6 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069672

Additional file 5 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069669

Additional file 3 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069663

Additional file 2 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069660

Additional file 1 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Yu, X., Lin, W., Spirtos, A. N., Wang, Y., Chen, H., Ye, J., Parker, J. E., Liu, C. C., Wang, Y., Quinn, G. M., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21069657

Additional file 1 of Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin

Franco‐Valls, H., Tusquets-Uxó, E., Sala, L., Val, M., Peña, R., Iaconcig, A., Villarino, Á., Jiménez-Arriola, M., Massó, P., Trincado, J. L., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26639965

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Licaj, M. (2021) · doi:10.70675/1fec630ez02e2z4a03z92bbze061df7c86cc

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Díaz-Palomera, C. D., Lucano, L. R. G., García-Bernal, J. R., de Arellano-Sánchez, J. A. R., Villegas‐Pineda, J. C., Villegas-Pacheco, R., Jave‐Suárez, L. F., & Pereira-Suárez, A. L. (2026) · Discover Oncology · doi:10.1007/s12672-026-04898-1

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Singh, D. K., Gupta, R., Kumar, U., & Gupta, S. (2026) · Clinical & Translational Oncology · doi:10.1007/s12094-026-04255-2 · Cited by 1 · see citing works

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Fiori, M. E., Franco, S. D., Villanova, L., Bianca, P., Stassi, G., & Maria, R. D. (2019) · Molecular Cancer · doi:10.1186/s12943-019-0994-2 · Cited by 648 · see citing works

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Soon, P. S. H., Kim, E., Pon, C. K., Gill, A. J., Moore, K., Spillane, A. J., Benn, D. E., & Baxter, R. C. (2012) · Endocrine Related Cancer · doi:10.1530/erc-12-0227 · Cited by 127 · see citing works

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Szabó, P. M., Vajdi, A., Kumar, N., Tolstorukov, M. Y., Chen, B. J., Edwards, R. H., Ligon, K. L., Chasalow, S. D., Chow, K.-H., Shetty, A., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-28480-9 · Cited by 65 · see citing works

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Tania, M., Khan, M. A., & Fu, J. (2014) · Tumor Biology · doi:10.1007/s13277-014-2163-y · Cited by 257 · see citing works