Epithelial–mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?

Macrophage plasticity and polarization: in vivo veritas

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EMT: 2016

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The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

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Emerging Biological Principles of Metastasis

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Functional Polarization of Tumour-Associated Macrophages by Tumour-Derived Lactic Acid

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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

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Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

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Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

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TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

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Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

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A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

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The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.

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Direct regulation of TWIST by HIF-1α promotes metastasis

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Epithelial–mesenchymal plasticity in carcinoma metastasisPreprint

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The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

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Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

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Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts

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ABC transporters in cancer: more than just drug efflux pumps

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Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

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The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

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Snail blocks the cell cycle and confers resistance to cell deathPreprint

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Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

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Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications

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Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

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Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex

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A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

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Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

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Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis

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Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells

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Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

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Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

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Twist Transcriptionally Up-regulates AKT2 in Breast Cancer Cells Leading to Increased Migration, Invasion, and Resistance to Paclitaxel

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Chronic Oxaliplatin Resistance Induces Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cell Lines

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A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition

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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expressionPreprint

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ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

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Tumor Budding: The Name is EMT. Partial EMT.

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Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer

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Multiple Drug Resistance Mechanisms in Cancer

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MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination

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G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

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TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

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ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

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MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling

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Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2

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miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

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Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells

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Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters

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EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

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Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling

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ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

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Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis

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The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine‐specific demethylase 1

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Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

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E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

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Evidence for a function of CtBP in epithelial gene regulation and anoikis

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Aberrant Expression of the Transcription Factors Snail and Slug Alters the Response to Genotoxic Stress

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Hypoxia‐inducing factors as master regulators of stemness properties and altered metabolism of cancer‐ and metastasis‐initiating cells

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Tumor promoting role of anti-tumor macrophages in tumor microenvironment

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Upholding a role for EMT in breast cancer metastasis

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Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks

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Metabolic reprogramming and epithelial‐to‐mesenchymal transition in cancer

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An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal States

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Regulation of lncRNA and Its Role in Cancer Metastasis

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Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

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Amplification of Long Noncoding RNA ZFAS1 Promotes Metastasis in Hepatocellular Carcinoma

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The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis

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Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

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TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis

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Coupled Reversible and Irreversible Bistable Switches Underlying TGFβ-induced Epithelial to Mesenchymal Transition

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Expression of Wnt3 Activates Wnt/β-Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells

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Upholding a role for EMT in pancreatic cancer metastasis

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Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer

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SET8 promotes epithelial–mesenchymal transition and confers TWIST dual transcriptional activities

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Levels of Gemcitabine Transport and Metabolism Proteins Predict Survival Times of Patients Treated With Gemcitabine for Pancreatic Adenocarcinoma

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