The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Epigenetic Reprogramming in Mammalian Development
Abstract
During the mid-twentieth century Conrad Waddington proposed his ontogenic concept of canalization, and suggested that epigenetic mechanisms might serve as a means of metastable memory imposed on the genetic material during differentiation. Subsequently, Waddington's theories have received substantial acknowledgment during the first decade of the twenty-first century, with numerous studies unraveling the important contributions of epigenetic mechanisms and the epigenomic control of differentiation. The early embryogenesis and primordial germ cell development have received much attention as developmental stages with extensive epigenomic reprogramming. In both developmental phases, the epigenomic landscape of chromosomes is rapidly and dramatically altered, and this goes along with a substantial change in the developmental potential of cells. In this chapter, a summary is provided of the current knowledge of epigenetic reprogramming mechanisms. These are discussed in line with biological concepts, and with the role of DNA methylation in particular.
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Cites
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Cited by
The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W., & Reik, W. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.11.001 · Cited by 973
Self-citationAcute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
Barrès, R., Yan, J., Egan, B., Treebak, J. T., Rasmussen, M., Fritz, T., Caidahl, K., Krook, A., O'Gorman, D. J., & Zierath, J. R. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.01.001 · Cited by 965
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
Pastor, W. A., Aravind, L., & Rao, A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3589 · Cited by 897
Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D., et al. (2011) · Cell · doi:10.1016/j.cell.2011.06.020 · Cited by 809
Koh, K. P., Yabuuchi, A., Rao, S., Huang, Y., Cunniff, K., Nardone, J., Laiho, A., Tahiliani, M., Sommer, C. A., Mostoslavsky, G., et al. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.01.008 · Cited by 776
Metadata
- Authors
- Lepikhov, K., Arand, J., Wossidlo, M., & Walter, J.
- Venue
- Encyclopedia of Molecular Cell Biology and Molecular Medicine
- Publisher
- Wiley-VCH Verlag GmbH & Co. KGaA
- Published
- 2012-05-15
- OpenAlex
- W2914618148
- Cited by
- 336
- References
- 7
- Type
- reference entry
- Language
- en
- Open access
- closed
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- Lepikhov, K., Arand, J., Wossidlo, M., & Walter, J. (2012). Epigenetic Reprogramming in Mammalian Development. Encyclopedia of Molecular Cell Biology and Molecular Medicine. https://doi.org/10.1002/3527600906.mcb.201100038
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