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Cited by 209

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Electrophoretic Separation of Nanoparticles with a Discrete Number of Functional Groups

Sperling, R. A., Pellegrino, T., Li, J. K., Chang, W. H., Parak, W. J.·2006·Advanced Functional Materials

Abstract

A concept is describe that facilitates the modification of colloidal nanoparticles of different materials with an exactly known number of variable functional groups. In particular, a procedure for the surface functionalization of nanoparticles with a controlled number of mono‐ or bifunctional poly(ethylene glycol) (PEG) molecules of suitable chain length is reported. Conjugates of nanoparticles with one, two, and three PEG molecules per nanoparticle could be separated using gel electrophoresis. Molecules with additional functionalities could be conjugated to the free ends of the bifunctional PEG molecules. In this way the PEG molecules act as convenient spacers that allow for the sorting of nanoparticles with a discrete number of functional groups.

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Metadata

Authors
Sperling, R. A., Pellegrino, T., Li, J. K., Chang, W. H., & Parak, W. J.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2006-04-12
Volume
16
Issue
7
Pages
943-948
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W2056120938
Cited by
209
References
0
FWCI
6.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Electrophoretic Separation of Nanoparticles with a Discrete Number of Functional Groups. https://app.cochat.ai/papers/10.1002/adfm.200500589
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Sperling, R. A., Pellegrino, T., Li, J. K., Chang, W. H., & Parak, W. J. (2006). Electrophoretic Separation of Nanoparticles with a Discrete Number of Functional Groups. Advanced Functional Materials. https://doi.org/10.1002/adfm.200500589

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.