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Cited by 271

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Self‐Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing

Zeng, Qiong, Cheng, Jinsheng, Tang, Longhua, Liu, Xiaofei, Liu, Yanzhe, Li, Jinghong, Jiang, Jianhui·2010·Advanced Functional Materials

Abstract

The self‐assembly of sodium dodecyl benzene sulphonate (SDBS) functionalized graphene sheets (GSs) and horseradish peroxidase (HRP) by electrostatic attraction into novel hierarchical nanostructures in aqueous solution is reported. Data from scanning electron microscopy, high‐resolution transmission electron microscopy, and X‐ray diffraction demonstrate that the HRP–GSs bionanocomposites feature ordered hierarchical nanostructures with well‐dispersed HRP intercalated between the GSs. UV‐vis and infrared spectra indicate the native structure of HRP is maintained after the assembly, implying good biocompatibility of SDBS‐functionalized GSs. Furthermore, the HRP–GSs composites are utilized for the fabrication of enzyme electrodes (HRP–GSs electrodes). Electrochemical measurements reveal that the resulting HRP–GSs electrodes display high electrocatalytic activity to H 2 O 2 with high sensitivity, wide linear range, low detection limit, and fast amperometric response. These desirable electrochemical performances are attributed to excellent biocompatibility and superb electron transport efficiency of GSs as well as high HRP loading and synergistic catalytic effect of the HRP–GSs bionanocomposites toward H 2 O 2. As graphene can be readily non‐covalently functionalized by “designer” aromatic molecules with different electrostatic properties, the proposed self‐assembly strategy affords a facile and effective platform for the assembly of various biomolecules into hierarchically ordered bionanocomposites in biosensing and biocatalytic applications.

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Metadata

Authors
Zeng, Q., Cheng, J., Tang, L., Liu, X., Liu, Y., Li, J., & Jiang, J.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2010-08-16
Volume
20
Issue
19
Pages
3366-3372
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W1966217624
Cited by
271
References
37
FWCI
23.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Self‐Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing. https://app.cochat.ai/papers/10.1002/adfm.201000540
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Zeng, Q., Cheng, J., Tang, L., Liu, X., Liu, Y., Li, J., & Jiang, J. (2010). Self‐Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing. Advanced Functional Materials. https://doi.org/10.1002/adfm.201000540

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