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Cited by 188

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Eradicating Multidrug‐Resistant Bacteria Rapidly Using a Multi Functional g‐C3N4@ Bi2S3 Nanorod Heterojunction with or without Antibiotics

Li, Yuan, Liu, Xiangmei, Tan, Lei, Cui, Zhenduo, Jing, Doudou, Yang, Xianjin, Liang, Yanqin, Li, Zhaoyang, Zhu, Shengli, Zheng, Yufeng, Yeung, Kelvin Wai Kwok, Zheng, Dong, Wang, Xianbao, Wu, Shuilin·2019·Advanced Functional Materials

Abstract

Wound infections caused by multidrug‐resistant (MDR) bacteria are hard to treat because of tolerance to existing antibiotics, repeated infection, and concomitant inflammation. Herein, zinc atom–doped g‐C 3 N 4 and Bi 2 S 3 nanorod heterojunctions (CN–Zn/BiS) are investigated for disinfection under near‐infrared light (NIR). The photocatalysis of CN–Zn/BiS is enhanced because of efficient charge separation during the interface electron field and increased oxygen adsorption capacity. Then, 99.2% antibacterial efficiency is shown toward methicillin‐resistant Staphylococcus aureus (MRSA) and 99.6% toward Escherichia coli under 10 min NIR irradiation. Meanwhile, a strategy for the combination of lapsed β‐lactam antibiotics with the photosensitizer CN–Zn/BiS is provided to kill MRSA by NIR without observable resistance, suggesting an approach to solve the problem of bacterial infection with NIR light penetrability and for exploiting new anti‐infection methods. The CN–Zn/BiS nanocomposite can also regulate genes and the inflammatory response through inflammatory factors (IL‐1β, IL‐6, TNF‐α, and iNOS) in vivo to accelerate tissue regeneration and thereby promote wound healing.

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Metadata

Authors
Li, Y., Liu, X., Tan, L., Cui, Z., Jing, D., Yang, X., Liang, Y., Li, Z., Zhu, S., Zheng, Y., Yeung, K. W. K., Zheng, D., Wang, X., & Wu, S.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2019-03-28
Volume
29
Issue
20
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W2927897792
Cited by
188
References
3
FWCI
5.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Eradicating Multidrug‐Resistant Bacteria Rapidly Using a Multi Functional g‐C3N4@ Bi2S3 Nanorod Heterojunction with or without Antibiotics. https://app.cochat.ai/papers/10.1002/adfm.201900946
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Li, Y., Liu, X., Tan, L., Cui, Z., Jing, D., Yang, X., Liang, Y., Li, Z., Zhu, S., Zheng, Y., Yeung, K. W. K., Zheng, D., Wang, X., & Wu, S. (2019). Eradicating Multidrug‐Resistant Bacteria Rapidly Using a Multi Functional g‐C3N4@ Bi2S3 Nanorod Heterojunction with or without Antibiotics. Advanced Functional Materials. https://doi.org/10.1002/adfm.201900946

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