The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Self‐Powered Iontophoretic Transdermal Drug Delivery System Driven and Regulated by Biomechanical Motions
Abstract
Transdermal drug delivery (TDD) systems with feedback control have attracted extensive research and clinical interest owing to their unique advantages of convenience, self‐administration, and safety. Here, a self‐powered wearable iontophoretic TDD system that can be driven and regulated by the energy harvested from biomechanical motions is proposed for closed‐loop motion detection and therapy. A wearable triboelectric nanogenerator (TENG) is used as the motion sensor and energy harvester that can convert biomechanical motions into electricity for iontophoresis without stored‐energy power sources, while a hydrogel‐based soft patch with side‐by‐side electrodes is designed to enable noninvasive iontophoretic TDD. Proof‐of‐concept experiments on pig skin with dyes as model drugs successfully demonstrate the feasibility of the proposed system. This work not only extends the application of TENG in the biomedical field, but may also provide a cost‐effective solution for noninvasive, electrically assisted TDD with closed‐loop sensing and treatment.
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Lee, H., Choi, T. K., Lee, Y. B., Cho, H. R., Ghaffari, R., Wang, L., Choi, H. J., Chung, T. D., Lu, N., Hyeon, T., et al. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.38 · Cited by 1,802
Sustainably powering wearable electronics solely by biomechanical energy
Wang, J., Li, S., Yi, F., Zi, Y., Lin, J., Wang, X., Xu, Y., & Wang, Z. L. (2016) · Nature Communications · doi:10.1038/ncomms12744 · Cited by 648
Self-citationBiodegradable triboelectric nanogenerator as a life-time designed implantable power source
Zheng, Q., Zou, Y., Zhang, Y., Liu, Z., Shi, B., Wang, X., Jin, Y., Ouyang, H., Li, Z., & Wang, Z. L. (2016) · Science Advances · doi:10.1126/sciadv.1501478 · Cited by 617
Self-citationStretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots
Di, J., Yao, S., Ye, Y., Cui, Z., Yu, J., Ghosh, T. K., Zhu, Y., & Gu, Z. (2015) · ACS Nano · doi:10.1021/acsnano.5b03975 · Cited by 253
Wang, W., Wat, E., Hui, P. C. L., Chan, B., Ng, F. S. F., Kan, C.-W., Wang, X., Hu, H., Wong, E. C. W., Lau, C. B. S., et al. (2016) · Scientific Reports · doi:10.1038/srep24112 · Cited by 130
Cited by
Advances in healthcare wearable devices
Iqbal, S. M. A., Mahgoub, I., Du, E., Leavitt, M. A., & Asghar, W. (2021) · npj Flexible Electronics · doi:10.1038/s41528-021-00107-x · Cited by 714
Choi, D., Lee, Y., Lin, Z.-H., Cho, S., Kim, M., Ao, C. K., Soh, S., Sohn, C., Jeong, C. K., Lee, J., et al. (2023) · ACS Nano · doi:10.1021/acsnano.2c12458 · Cited by 656
Self-citationYu, Y.-Q., Yang, X., Wu, X.-F., & Fan, Y.-B. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.646554 · Cited by 441
Porous Conductive Textiles for Wearable Electronics
Ding, Y., Jiang, J., Wu, Y., Zhang, Y., Zhou, J., Zhang, Y., Huang, Q., & Zheng, Z. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00507 · Cited by 269
Design, manufacturing and applications of wearable triboelectric nanogenerators
Wang, H., Han, M., Song, Y., & Zhang, H. (2021) · Nano Energy · doi:10.1016/j.nanoen.2020.105627 · Cited by 179
Metadata
- Authors
- Wu, C., Jiang, P., Li, W., Guo, H., Wang, J., Chen, J., Prausnitz, M. R., & Wang, Z. L.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2019-10-25
- Volume
- 30
- Issue
- 3
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2981853637
- Cited by
- 167
- References
- 5
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wu, C., Jiang, P., Li, W., Guo, H., Wang, J., Chen, J., Prausnitz, M. R., & Wang, Z. L. (2020). Self‐Powered Iontophoretic Transdermal Drug Delivery System Driven and Regulated by Biomechanical Motions. Advanced Functional Materials. https://doi.org/10.1002/adfm.201907378
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
