The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Inorganic Nanoparticles Based Contrast Agents for X‐ray Computed Tomography
Abstract
Nanomaterials have gained considerable attention and interest in the development of new and efficient molecular probes for medical diagnosis and imaging. Heavy metal nanoparticles as such are excellent absorber of X‐rays and can offer excellent improvement in medical diagnosis and X‐ray imaging. Substantial progress has been made in the synthesis protocol and characterization studies of these materials but a major challenge still lies in the toxicological studies, which are rather incomplete. The worst known cases were those associated with Thorotrast (suspension of ThO 2 nanoparticles) which resulted in many deaths over years. Properly protected nanomaterials conjugated or coated with biocompatible materials can be used for the fabrication of various functional systems with multimodality, targeting properties, reduced toxicity and proper removal from the body. This review aims mainly to provide the advances in the development of inorganic nanoparticle based X‐ray contrasting agents with an overview of methods of their preparation, functionalization and applications in medical diagnosis.
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Kittler, S., Greulich, C., Diendorf, J., Köller, M., & Epple, M. (2010) · Chemistry of Materials · doi:10.1021/cm100023p · Cited by 1,126
Nanocrystal Core High-Density Lipoproteins: A Multimodality Contrast Agent Platform
Cormode, D. P., Skajaa, T., van Schooneveld, M. M., Koole, R., Jarzyna, P., Lobatto, M. E., Calcagno, C., Barazza, A., Gordon, R. E., Zanzonico, P., et al. (2008) · Nano Letters · doi:10.1021/nl801958b · Cited by 328
Computed Tomography in Color: NanoK‐Enhanced Spectral CT Molecular Imaging
Pan, D., Roessl, E., Schlomka, J., Caruthers, S. D., Senpan, A., Scott, M. J., Allen, J. S., Zhang, H., Hu, G., Gaffney, P. J., et al. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201005657 · Cited by 178
Cited by
Shahbazi, M.-A., Faghfouri, L., Ferreira, M. P. A., Figueiredo, P., Maleki, H., Sefat, F., Hirvonen, J., & Santos, H. A. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00283a · Cited by 523
Applications of nanoparticles for diagnosis and therapy of cancer
Baetke, S. C., Lammers, T., & Kiessling, F. (2015) · The British Journal of Radiology · doi:10.1259/bjr.20150207 · Cited by 494
Dou, Y., Guo, Y., Li, X., Li, X., Wang, S., Wang, L., Lv, G., Zhang, X., Wang, H., Gong, X., et al. (2016) · ACS Nano · doi:10.1021/acsnano.5b07473 · Cited by 288
Nanoparticles for Imaging: top or Flop?
Kiessling, F., Mertens, M. E., Grimm, J., & Lammers, T. (2014) · Radiology · doi:10.1148/radiol.14131520 · Cited by 228
Metadata
- Authors
- Jakhmola, A., Anton, N., & Vandamme, T. F.
- Venue
- Advanced Healthcare Materials
- Publisher
- Wiley
- Published
- 2012-05-18
- Volume
- 1
- Issue
- 4
- Pages
- 413-431
- ISSN
- 2192-2640 (ISSN-L)
- 2192-2659
- OpenAlex
- W2090877998
- Cited by
- 184
- References
- 3
- FWCI
- 7.67
- Type
- journal article
- Language
- en
- Open access
- closed
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