The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Mechanically Robust, Negative‐Swelling, Mussel‐Inspired Tissue Adhesives
Open accessAbstract
Most synthetic polymer hydrogel tissue adhesives and sealants swell considerably in physiologic conditions, which can result in mechanical weakening and adverse medical complications. This paper describes the synthesis and characterization of mechanically tough zero‐ or negative‐swelling mussel‐inspired surgical adhesives based on catechol‐modified amphiphilic poly(propylene oxide)‐poly(ethylene oxide) block copolymers. The formation, swelling, bulk mechanical, and tissue adhesive properties of the resulting thermosensitive gels were characterized. Catechol oxidation at or below room temperature rapidly resulted in a chemically cross‐linked network, with subsequent warming to physiological temperature inducing a thermal hydrophobic transition in the PPO domains and providing a mechanism for volumetric reduction and mechanical toughening. The described approach can be easily adapted for other thermally sensitive block copolymers and cross‐linking strategies, representing a general approach that can be employed to control swelling and enhance mechanical properties of polymer hydrogels used in a medical context.
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Cites
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
Peppas, N. A., Hilt, J. Z., Khademhosseini, A., & Langer, R. (2006) · Advanced Materials · doi:10.1002/adma.200501612 · Cited by 4,109
Holten-Andersen, N., Harrington, M. J., Birkedal, H., Lee, B. P., Messersmith, P. B., Lee, K. Y. C., & Waite, J. H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015862108 · Cited by 1,597
Self-citationCatechol-functionalized chitosan/pluronic hydrogels for tissue adhesives and hemostatic materials
Ryu, J. H., Lee, Y., Kong, W. H., Kim, T. G., Park, T. G., & Lee, H. (2011) · Biomacromolecules · doi:10.1021/bm200464x · Cited by 677
Cross-Linking in Adhesive Quinoproteins: Studies with Model Decapeptides
Burzio, L. A., & Waite, J. H. (2000) · Biochemistry · doi:10.1021/bi0002434 · Cited by 485
Papov, V. V., Diamond, T. V., Biemann, K., & Waite, J. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.34.20183 · Cited by 329
Chiappetta, D. A., Facorro, G., Rubin de Celis, E., & Sosnik, A. (2011) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2011.01.017 · Cited by 96
Cited by
Han, L., Liu, K., Wang, M., Wang, K., Fang, L., Chen, H., Zhou, J., & Lu, X. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201704195 · Cited by 1,160
The chemistry behind catechol-based adhesion
Saiz‐Poseu, J., Mancebo‐Aracil, J., Nador, F., Busqué, F., & Ruiz‐Molina, D. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201801063 · Cited by 850
Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764
Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein
Kord Forooshani, P., & Lee, B. P. (2017) · Journal of Polymer Science Part A: Polymer Chemistry · doi:10.1002/pola.28368 · Cited by 632
Mussel‐Inspired Hydrogels for Self‐Adhesive Bioelectronics
Xie, C., Wang, X., He, H., Ding, Y., & Lu, X. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201909954 · Cited by 482
Metadata
- Authors
- Barrett, D. G., Bushnell, G. G., & Messersmith, P. B.
- Venue
- Advanced Healthcare Materials
- Publisher
- Wiley
- Published
- 2012-11-23
- Volume
- 2
- Issue
- 5
- Pages
- 745-755
- ISSN
- 2192-2640 (ISSN-L)
- 2192-2659
- OpenAlex
- W2150757642
- Cited by
- 220
- References
- 6
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- green
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