Bone tissue engineering: electrospun polycaprolactone 3D nanofibrous scaffold with interconnected and hierarchically structured pores for bone tissue engineering (Adv. Healthcare Mater. 15/2015)
Abstract
On page 2238, H. Sun, H. Fong, and co-workers report that electrospun PCL 3D nanofibrous scaffold with interconnected and hierarchically structured pores is morphologically/structurally similar to natural extracellular matrix (ECM), hence well-suited for cell functions and tissue formation. The in vitro results indicate that the novel scaffold supports mouse bone marrow mesenchymal stem cells' osteogenic differentiation, while the in vivo results suggest that it acts as favorable synthetic ECM for the physiological process of endochondral ossification.
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- Authors
- Xu, T., Miszuk, J. M., Zhao, Y., Sun, H., & Fong, H.
- Affiliations
- South Dakota School of Mines and Technology (US)
- University of South Dakota (US)
- Corresponding author
- Sun, Hongli
- Fong, Hao
- Venue
- Advanced Healthcare Materials
- Publisher
- Wiley
- Published
- 2015-10
- Volume
- 4
- Issue
- 15
- Pages
- 2237-2237
- ISSN
- 2192-2640 (ISSN-L)
- 2192-2659
- OpenAlex
- W1889165435
- Cited by
- 12
- References
- 0
- Citations by year
- 2022: 2 · 2021: 1 · 2020: 1 · 2019: 4 · 2018: 1 · 2016: 3
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Healthcare Materials (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Keywords
- bone tissue engineering, polycaprolactone, electrospun nanofibrous scaffolds, hierarchical porous structure, interconnected pores, extracellular matrix mimicry, mesenchymal stem cells, osteogenic differentiation, endochondral ossification, synthetic extracellular matrix
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