Cited by 499Internet of Things and AITechnology and Human Factors in Education and HealthDigital Transformation in Industry

Medical 4.0 technologies for healthcare: Features, capabilities, and applications

Open access
Haleem, Abid, Javaid, Mohd, Pratap Singh, Ravi, Suman, Rajiv·2022·Internet of Things and Cyber-Physical Systems

Abstract

The Fourth Industrial Revolution may help many sectors and industries, whereas healthcare will be significantly impacted. Medical advances will be swifter, better and more effective, quickly providing medications to patients. It will act as a leveller for healthcare services by making them available to everybody. Medical 4.0 is the fourth medical revolution, employing emerging technologies to create significant advancements in healthcare. New medical 4.0 technology has advanced significantly, ranging from mobile computing to cloud computing, over the previous decade and is now ready to be employed as commercially accessible, networked systems. Expanding and with higher life expectancies, there is an enormous need for improved healthcare for older populations. This paper explores Medical 4.0 and its demand in the healthcare sector and discusses various progressive steps for Medical 4.0 implementation. Smart and Advanced Features of Medical 4.0 Practices are discussed diagrammatically. Medical 4.0 envisions a strongly interconnected health system. A hospital bed can be connected to the network and use patient data via the Internet of Things (IoT). Finally, this paper explores & provides the significant applications of Medical 4.0 for healthcare services. In addition to being creative, Medical 4.0 decreases the healthcare burden in affluent nations and offers good services to less developed countries, providing comprehensive and high-quality treatment. Medical 4.0 is characterised by technical discoveries and developments in the medical profession to encourage patient-centred therapy and drugs. This digital transformation, where patients' data will be electronically collected and utilised by technology to better understand and diagnose them, replaces the doctor-centric treatment techniques with a patient-centric paradigm.

Verified 2026-10-09 · 1 reference not checked yet

AI snapshot

Written from the paper’s full text.

TL;DR

This review describes Medical 4.0 as the fourth medical revolution, using emerging technologies such as IoT, AI, VR, big data, 5G, robotics, and blockchain to create interconnected, patient-centred healthcare. It discusses the need for Medical 4.0, progressive implementation steps, smart features, and applications across telemedicine, wearables, AI, data science, IoT, RPA, VR, edge computing, intelligent apps, additive manufacturing, 3D scanning, tissue engineering, big data, 5G, drones, nanomedicine, IoB, cybersecurity, and blockchain.

Key findings

  • Medical 4.0 is characterised as a patient-centric digital transformation that replaces doctor-centric treatment techniques, aiming to make healthcare more available, accurate, individualised, and lower cost; no numerical outcomes are reported.
  • The paper identifies progressive implementation steps: patient data collection and past medical records, processing with smart systems such as AI, machine learning, IoT, and cloud computing, then compilation of analysed data into improved patient records.
  • It lists major applications including telemedicine, sensors and wearable technology, artificial intelligence, data science, IoT, robotic process automation, virtual reality, edge computing, intelligent apps, additive manufacturing, 3D scanning, tissue engineering, big data, 5G, drones, nanomedicine, Internet of Behaviours, cybersecurity, and blockchain.
  • The paper states Medical 4.0 is still in its early stages and that a comprehensive picture may not yet exist.

Methods

  • Literature review-based study using Scopus, Google Scholar, Science Direct, Research Gate, and other databases.
  • Search terms included “Medical 4.0 technologies (All technologies)” and “Healthcare”; the most relevant papers were selected and critically discussed.
  • No primary data, sample size, or quantitative analysis is reported.

Limitations

  • The paper states that smart technologies have limitations, as do the humans who power them; human skill and learning curves differ, and innate strengths in traditional work may not translate proportionally when innovative technology is introduced.
  • The paper states that digital transformation will be widespread but slower than the Internet’s digital disruption, and that companies are often conservative due to extensive investment cycles.
  • Evident from the text: the review lacks a systematic review protocol, explicit inclusion/exclusion criteria, and empirical validation; many claims are broad and supported by narrative citation rather than reported outcomes.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1016/j.iotcps.2022.04.001

Cites

382 of 383 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 123 cited sources checked · 0 supported · 0 flagged

  • Premisecitation

    Medical 4.0 technologies are evolving into a patient-centred approach in which data will be provided to industry participants to develop better technology and healthcare delivery concepts.

    “These technologies are evolving into a patient-centred approach in which the data will be provided to industry participants to develop better technology and healthcare delivery concepts [28,29].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [28] Yang, 2020, Homecare robotic systems for healthcare 4.0: visions and enabling technologies, IEEE J. biomed. health inform. source

      Not checked in the free run.

    • cites [29] Hathaliya, 2020, An exhaustive survey on security and privacy issues in Healthcare 4.0, Comput. Commun. source

      Not checked in the free run.

  • Premisecitation

    AI is transforming the healthcare domain by allowing clinicians to stay focused on the most critical patient care and requirements rather than being distracted by different priorities of the same patients.

    “AI is transforming the healthcare domain by allowing clinicians to stay focused on the most critical patient care and requirements rather than being distracted by different priorities of the same patients [60,61].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [60] Weaver, 2010, Forgoing medical care because of cost: assessing disparities in healthcare access among cancer survivors living in the United States, Cancer source

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    • cites [61] Singh, 2020, Internet of things (IoT) applications to fight against COVID-19 pandemic, Diabetes Metabol. Syndr.: Clin. Res. Rev. source

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  • Interpretationcitation

    As technology progresses, more people will have access to high-quality healthcare at a lesser cost.

    “As technology progresses, more people will have access to high-quality healthcare at a lesser cost.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites [47][48][49]

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  • Interpretationreasoning

    Medical 4.0 can improve health care by offering more accurate and individualised care.

    “Medical 4.0 can improve health care by offering more accurate and individualised care.”
    Quote in the paperSubstantial claim
  • Premisecitation

    AI technologies enable virtual nursing assistants to undertake various activities, from talking with patients to guiding them to the most appropriate and effective care unit.

    “AI technologies enable virtual nursing assistants to undertake various activities, from talking with patients to guiding them to the most appropriate and effective care unit.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [125] Li, 2020, Developing a delivery science for artificial intelligence in healthcare, NPJ dig. med.

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    • cites [126] Longoni, 2019, Resistance to medical artificial intelligence, J. Consum. Res. source

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  • Classified as probably not a substantial claim. 55
  • May combine two claims. 44
  • The quote only partly states this claim. 1
  • Probably not a substantial claim: may not pass S4 (based).

    Interpretationreasoning

    This digital transformation replaces doctor-centric treatment techniques with a patient-centric paradigm.

    “This digital transformation, where patients' data will be electronically collected and utilised by technology to better understand and diagnose them, replaces the doctor-centric treatment techniques with a patient-centric paradigm.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationnone given

    Medical 4.0 uses modern technologies to connect patients and healthcare professionals to the organisation and treatment technique.

    “Medical 4.0 uses modern technologies to connect patients and healthcare professionals to the organisation and treatment technique.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Medical 4.0 technology has advanced significantly over the previous decade and is now ready to be employed as commercially accessible, networked systems.

    “Healthcare technologies, ranging from mobile computing to cloud computing, have advanced significantly over the previous decade and are now ready for deployment as commercially accessible.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [75] Bahl, 2020, Telemedicine technologies for confronting COVID-19 pandemic: a review, J. Ind. Integr. Manage. source

      Not checked in the free run.

    • cites [76] Aceto, 2020, Industry 4.0 and health: internet of things, big data, and cloud computing for healthcare 4.0, J. Ind. Inform. Integr.

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  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationnone given

    Medical 4.0 is characterised by technical discoveries and developments in the medical profession to encourage patient-centred therapy and drugs.

    “Medical 4.0 is characterised by technical discoveries and developments in the medical profession to encourage patient-centred therapy and drugs.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    VR has demonstrated proven pain management efficacy and showed vital improvement in chronic pain patients.

    “Aside from providing patients with an escape route, VR has also demonstrated proven pain management efficacy and showed vital improvement in chronic pain patients.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [32][33][34]

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  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Medical 4.0 decreases the healthcare burden in affluent nations and offers good services to less developed countries, providing comprehensive and high-quality treatment.

    “In addition to being creative, Medical 4.0 decreases the healthcare burden in affluent nations and offers good services to less developed countries, providing comprehensive and high-quality treatment.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationcitation

    The deployment of Medical 4.0 technologies will allow for significant advancements in therapies and make them available to more persons at an affordable price.

    “The advantages are vast, and the deployment of these technologies will allow for significant advancements in the therapies and make them available to more persons at an affordable price [17,20].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [17] Wehde, 2019, Healthcare 4.0, IEEE Eng. Manag. Rev. source

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    • cites [20] Singh, 2020, Significance of health information technology (HIT) in context to COVID-19 pandemic: potential roles and challenges, J. Ind. Integr. Manage. source

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  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Wearables and other IoMT devices help doctors to access extensive patient information remotely.

    “Wearables and other IoMT devices help doctors to access extensive patient information remotely.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Predictive analytics might help hospitals and clinics forecast admission rates to enhance staff scheduling.

    “Predictive analytics might help hospitals and clinics forecast admission rates to enhance staff scheduling [34][35][36].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [34][35][36]

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  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Medical 4.0 is emerging as a new trend in the healthcare field, where the Healthcare sector can benefit from cloud computing that employs artificial intelligence.

    “Medical 4.0 is emerging as a new trend in the healthcare field, where the Healthcare sector can benefit from cloud computing that employs artificial intelligence.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Wearable gadgets provide healthcare staff with real-time patient data while still at home.

    “Wearable gadgets provide healthcare staff with real-time patient data while still at home.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Hospitals can use IoT to automate production operations and reduce the overall cost of hiring a gardener team.

    “The hospitals can use IoT to automate production operations and reduce the overall cost of hiring a gardener team.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationreasoning

    Because of data, medical research will grow tremendously.

    “Because of data, medical research will likewise grow tremendously.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    One of the primary advantages of telehealth over in-person options is that it limits contact between patients, healthcare personnel, and other patients while still offering a significant patient experience.

    “One of the primary advantages of telehealth over in-person options is that it limits contact between patients, healthcare personnel, and other patients while still offering a significant patient experience.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Connecting medical areas to technology equipment enable healthcare providers to introduce a more precise therapy method.

    “Connecting medical areas to technology equipment enable healthcare providers to introduce a more precise therapy method.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Premisenone given

    Medical 4.0 technologies include wearables, applications, and mobile technologies that give access to health care assistance and monitoring, growing in popularity, particularly for managing long-term and chronic illnesses.

    “Medical 4.0 technologies include wearables, applications, and mobile technologies that give access to health care assistance and monitoring, growing in popularity, particularly for managing long-term and chronic illnesses.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationnone given

    Wearable technology predicts future ill-health endpoints in patients, and expert systems technology allows the impart of best practices.

    “Wearable technology predicts future ill-health endpoints in patients, and expert systems technology allows the impart of best practices.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationnone given

    A digital twin allows remote monitoring and operating equipment and systems by providing a near real-time bridge between the physical and digital worlds.

    “This technology allows remote monitoring and operating equipment and systems by providing a near real-time bridge between the physical and digital worlds.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    Blockchain can significantly enhance the healthcare business.

    “Blockchain is a movement that can significantly enhance the healthcare business.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationcitation

    Communication between healthcare practitioners and patients has become much easier because of advances in medical technologies.

    “Communication between healthcare practitioners and patients has become much easier because of advances in medical technologies [78,79].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [78] Zheng, 2013, Emerging wearable medical devices towards personalized healthcare

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    • cites [79] Jain, 2021, Adoption of fog computing in healthcare 4.0

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  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Premisenone given

    Companies that use digital twins for significant benefits include enhanced operations, product and service innovation, and faster time-to-market.

    “Companies that use digital twins for significant benefits include enhanced operations, product and service innovation, and faster time-to-market.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationcitation

    IoT devices in healthcare, such as wearable fitness bands, pulsometers, digital thermometers, and other related health equipment, elevate individuals' selfcare efforts.

    “IoT devices in healthcare, such as wearable fitness bands, pulsometers, digital thermometers, and other related health equipment, elevate individuals' selfcare efforts.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Interpretationreasoning

    Medical 4.0 technologies monitor patients and administer individualised care.

    “Medical 4.0 technologies monitor patients and administer individualised care.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationnone given

    5G can let IoT devices connect and communicate faster.

    “5G can let IoT devices connect and communicate faster.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S4 (based). May combine two claims.

    Interpretationnone given

    Medical 4.0 technologies help to provide individualised therapy, address symptoms rapidly and monitor patients' health minute by minute in real-time.

    “Medical 4.0 technologies help to provide individualised therapy, address symptoms rapidly and monitor patients' health minute by minute in real-time.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    Technologies of Medical 4.0 are to improve operating performance, including health and safety performance.

    “Technologies of Medical 4.0 are to improve operating performance, including health and safety performance.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationreasoning

    The development of wearables and sensors has heralded a new age of telemedicine.

    “The development of wearables and sensors has heralded a new age of telemedicine.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Interpretationnone given

    IoT devices capture data and transmit it for examination and effective medicine, providing healthcare practitioners with a more accurate reflection of various healthcare applications and diagnoses.

    “IoT devices capture data and transmit it for examination and effective medicine, providing healthcare practitioners with a more accurate reflection of various healthcare applications and diagnoses.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationreasoning

    Telemedicine applications have become critical for millions of individuals worldwide regarding health promotion and illness prevention.

    “Telemedicine applications have become critical for millions of individuals worldwide regarding health promotion and illness prevention.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Telehealth services have grown in popularity in recent years, as Covid-19 has made individuals worldwide more worried about their general health.

    “Telehealth services have grown in popularity in recent years, as Covid-19 has made individuals worldwide more worried about their general health [90][91][92][93][94][95].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [90][91][92][93][94][95]

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    Premisecitation

    AI can improve surgery speed and help doctors perform delicate incisions.

    “AI can also improve surgery speed and help doctors perform delicate incisions [121][122][123][124].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [121][122][123][124]

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    Premisecitation

    AI has been employed to automate the most mundane and repetitive processes and reduce paperwork.

    “Initially, AI has been employed to automate the most mundane and repetitive processes and reduce paperwork.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [116][117][118][119][120]

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  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisenone given

    Telemedicine enables healthcare practitioners to examine, diagnose, and treat patients without seeing them.

    “Telemedicine enables healthcare practitioners to examine, diagnose, and treat patients without seeing them.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    AI-powered medical chatbots can provide patients with instant answers to many health-related queries and guide patients, saving unnecessary trips to the doctor and healthcare centre.

    “AI-powered medical chatbots service can provide patients with instant answers to many of their healthrelated queries and guide patients with any potential problems, saving on unnecessary trips to the doctor and healthcare centre.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [121][122][123][124]

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    Premisecitation

    AI can analyse enormous amounts of data to create knowledge databases and ease evaluation and advice for each patient, improving clinical decision support.

    “Artificial intelligence can analyse the enormous amounts of data, which may be used to create knowledge databases and ease evaluation and advice for each patient, improving clinical decision support.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [121][122][123][124]

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    Premisecitation

    Wireless sensors from Sensor Metrix are used in hospital refrigerators, freezers, and labs to keep blood samples, pharmaceuticals, and other items at the right temperature.

    “Wireless sensors from Sensor Metrix are used in hospital refrigerators, freezers, and labs to keep blood samples, pharmaceuticals, and other items at the right temperature [100][101][102].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [100][101][102]

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    Premisecitation

    Predictive analytics can be helpful to improve patient care, chronic illness management, the efficiency of supply chains and pharmaceutical logistics.

    “This predictive analytics can be helpful to improve patient care, chronic illness management, the efficiency of supply chains and pharmaceutical logistics.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [143][144][145]

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  • May combine two claims.

    Premisereasoning

    IoT offers real-time alerting, tracking, and monitoring, allowing for hands-on treatments, improved accuracy, timely intervention by doctors, and improved overall patient care delivery results.

    “As a result, IoT offers real-time alerting, tracking, and monitoring, allowing for hands-on treatments, improved accuracy, timely intervention by doctors, and improved overall patient care delivery results.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [166][167][168][169]

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    Premisecitation

    Internet of Things (IoT) in healthcare offers interoperability, machine-to-machine connection, information sharing, and data migration, which contribute to the effectiveness of healthcare service delivery.

    “Internet of Things (IoT) in healthcare offers interoperability, machine-to-machine connection, information sharing, and data migration, which contribute to the effectiveness of healthcare service delivery.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [155][156][157][158]

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    Premisecitation

    Data Science is critical in monitoring patients' health and informing essential measures to avoid potential illnesses.

    “Data Science is critical in monitoring patients' health and informing essential measures to be made to avoid potential illnesses from occurring.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [146] Kostkova, 2016, Who owns the data? Open data for healthcare, Front. Public Health source

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    • cites [147] Kim, 2017, Identifying and prioritizing critical factors for promoting the implementation and usage of big data in healthcare, Inf. Dev. source

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    Premisecitation

    Medical IoT devices collect vital indicators of any ailment and transmit that data to clinicians for real-time surveillance, while mobile applications and smart sensors notify individuals about key portions.

    “Medical IoT devices collect vital indicators of any ailment and transmit that data to clinicians for real-time surveillance, while mobile applications and smart sensors notify individuals about key portions [155][156][157][158].”
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    • cites [155][156][157][158]

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    Premisecitation

    One of IoT's most critical difficulties in healthcare is data security and privacy.

    “One of IoT's most critical difficulties in healthcare is data security and privacy.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [170][171][172][173][174]

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    Premisecitation

    RPA may automate registration procedures, maintain and manage medical information, and perform repetitive data entry.

    “RPA may automate registration procedures, maintain and manage medical information, and perform repetitive data entry.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [184][185][186]

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    Premisecitation

    By automating time-consuming and everyday activities such as data digitisation and payable accounts, RPA will improve billing performance, reduce write-offs and save healthcare providers.

    “By automating time-consuming and everyday activities such as data digitisation and payable accounts, RPA will improve billing performance, reduce write-offs and save healthcare providers.”
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    • cites [190][191][192]

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    Premisecitation

    Edge computing can be vital in times like the flu pandemic, where clinicians can monitor patients' vitals from remote areas and devise an action plan.

    “Edge computing can be vital in times like the flu pandemic, where clinicians can monitor patients' vitals from remote areas and devise an action plan.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [219] Sodhro, 2019, Mobile edge computing based QoS optimization in medical healthcare applications, Int. J. Inf. Manag.

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    • cites [220] Ray, 2019, Edge computing for Internet of Things: a survey, e-healthcare case study and future direction, J. Netw. Comput. Appl. source

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    Premisecitation

    Providing adequate healthcare to distant rural regions has always been difficult.

    “Providing adequate healthcare to distant rural regions has always been difficult [219,220].”
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    • cites [219] Sodhro, 2019, Mobile edge computing based QoS optimization in medical healthcare applications, Int. J. Inf. Manag.

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    • cites [220] Ray, 2019, Edge computing for Internet of Things: a survey, e-healthcare case study and future direction, J. Netw. Comput. Appl. source

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    Premisecitation

    VR-enabled virtual clinics have become more popular, and treating physical disorders at home using VR equipment yields promising results and is being expanded to other physical diseases.

    “VR-enabled virtual clinics have become more popular; treating physical disorders at home using VR equipment yields promising results and is being expanded to other physical diseases [205,206].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [205] Pillai, 2019, Impact of virtual reality in healthcare: a review, Virt. Augmented Real. Mental Health Treat. source

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    • cites [206] Bracq, 2019, Virtual reality simulation in nontechnical skills training for healthcare professionals: a systematic review, Simulat. Healthc. J. Soc. Med. Simulat. source

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    Premisecitation

    Exposure therapy is now considered a standard treatment method for several mental illnesses.

    “Exposure therapy is now considered a standard treatment method for several mental illnesses [210][211][212][213].”
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    • cites [210][211][212][213]

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    Premisecitation

    The biomedical and biotechnology domains are critical to developing successful regeneration therapeutics.

    “The biomedical and biotechnology domains are critical to developing successful regeneration therapeutics [268,269].”
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    • cites [268] Fernandes, 2018, Bioactive glasses and glass ceramics for bone regeneration and tissue engineering healthcare applications, Materials source

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    • cites [269] Xu, 2015, Bone tissue engineering: electrospun polycaprolactone 3D nanofibrous scaffold with interconnected and hierarchically structured pores for bone tissue engineering (Adv. Healthcare Mater. 15/2015), Adv. Healthc. Mater. source

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    Premisecitation

    Additive Manufacturing (AM) creates complex structures that vary in complexity, customisation, lightweight, strength, and speed for medical devices and other essential development.

    “Additive Manufacturing (AM) creates complex structures that vary in complexity, customisation, lightweight, strength, and speed, as additive manufacturing for medical devices and other essential development.”
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    • cites [243][244][245]

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    Premisecitation

    By keeping many critical processing jobs on network edge devices, healthcare IT infrastructures may still benefit from acquiring health-related data while also receiving quick, real-time analytics to detect and respond to health problems.

    “By keeping many critical processing jobs on network edge devices, healthcare IT infrastructures may still benefit from acquiring healthrelated data while also receiving quick, real-time analytics to detect and respond to health problems.”
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    • cites [224][225][226][227]

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    Premisecitation

    Intelligent apps provide a new approach to tailored health, bolstered by advanced AI, human medical expertise, and the power of mobile technology.

    “These apps provide a new approach to tailored health, bolstered by advanced AI, human medical expertise, and the power of mobile technology.”
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    • cites [233][234][235]

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    Premisecitation

    3D scanning provides doctors with a precise image of their patients and thoroughly researches potential treatments without physically testing them on the patient.

    “3D scanning provides doctors with a precise image of their patients and thoroughly researches potential treatments without physically testing them on the patient.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [258] Treleaven, 2007, 3D body scanning and healthcare applications, Computer source

      Not checked in the free run.

    • cites [259] Grazioso, 2018, Design and development of a novel body scanning system for healthcare applications, Int. J. Interact. Des. Manuf. source

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Population movements may be predicted using the GPS tracker, and the transmission of the infection can be limited.

    “Population movements may be predicted using the GPS tracker, and the transmission of the infection can be limited.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [284][285][286][287]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Tissue engineering helps functionalise tissues by mixing scaffolds, cells, and physiologically active chemicals.

    “It helps functionalising tissues by mixing scaffolds, cells, and physiologically active chemicals [270,271].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [270] Archer, 2005, Why tissue engineering needs process engineering, Nat. Biotechnol. source

      Not checked in the free run.

    • cites [271] Sridhar, 2015, Tissue engineering: development of a cellularly degradable PEG hydrogel to promote articular cartilage extracellular matrix deposition (Adv. Healthcare Mater. 5/2015), Adv. healthc. mater. source

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Non-therapeutic uses of tissue engineering include using tissues as biosensors to detect biological or chemical danger agents and tissue chips that may assess experimental medicine's toxicity.

    “Non-therapeutic uses include using tissues as biosensors to detect biological or chemical danger agents and tissue chips that may assess experimental medicine's toxicity [278][279][280].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [278][279][280]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Big data contributes to better results and lowers costs through improved disease management strategies.

    “It contributes to better results and lowers costs through improved disease management strategies.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [291][292][293]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    The pace, complexity, and volume of data flow and business operations will be boosted in the 5G era.

    “However, the pace, complexity, and volume of data flow and business operations will be boosted in this new era [303][304][305].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [303][304][305]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Nanotechnology is beneficial for healthcare applications in developing countries.

    “Nanotechnology is beneficial for healthcare applications in developing countries [336][337][338][339].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [336][337][338][339]

      Not checked in the free run.

  • The quote only partly states this claim.

    Premisecitation

    Big data will be highly beneficial to insurance firms by preventing a broad spectrum of insurance fraud claims.

    “It will also be highly beneficial to insurance firms.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [298][299][300][301]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    AR-powered medical devices and realtime data readings can remotely coach surgeons during surgery.

    “AR-powered medical devices and realtime data readings can remotely coach surgeons during surgery.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [315][316][317]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Drones can transfer medicine within hospital boundaries, transmit blood between hospital buildings, and provide elderly patients with gadgets to help them age in situ.

    “They can transfer medicine within hospital boundaries, transmit blood between hospital buildings, and provide elderly patients with gadgets to help them age in situ [329][330][331].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [329][330][331]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Nanoparticles can be used in various medical applications, including novel diagnostic tools, imaging agents and procedures, targeted medication delivery, medicines, bio-implants, and tissue engineering.

    “Nanoparticles can be used in various medical applications, including novel diagnostic tools, imaging agents and procedures, targeted medication delivery, medicines, bio-implants, and tissue engineering [332][333][334][335].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [332][333][334][335]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    The cloud's fast, frictionless scalability allows it to accommodate massive volumes of data involved in contemporary healthcare while utilising computing and storage resources as a service, enabling healthcare companies to react swiftly and cost-effectively to changing demands.

    “The cloud's fast, frictionless scalability allows it to accommodate the massive volumes of data involved in contemporary healthcare while utilising computing and storage resources as a service, enabling healthcare companies to react swiftly and cost-effectively to changing demands [306][307][308].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [306][307][308]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Nanostructure scaffolds are used for tissue replacement, and nanostructures that allow transport across biological barriers are novel nanotechnology applications.

    “Nanostructure scaffolds are used for tissue replacement, and nanostructures that allow transport across biological barriers are novel nanotechnology applications.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [340][341][342][343]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    With the arrival of 5G, healthcare businesses will have access to a more excellent range of apps, data, and infrastructure, allowing them to gain a competitive edge.

    “With the arrival of 5G, healthcare businesses will have access to a more excellent range of apps, data, and infrastructure, allowing them to gain a competitive edge [302].”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [302] Latif, 2017, How 5g wireless (and concomitant technologies) will revolutionize healthcare?, Future Internet source

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    5G will enable workloads to be provided from the cloud, lowering healthcare costs while increasing treatment quality and patient outcomes.

    “These are just a few of the workloads that 5G will enable to be provided from the cloud, lowering healthcare costs while increasing treatment quality and patient outcomes.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [309] Ahad, 2019, 5G-based smart healthcare network: architecture, taxonomy, challenges and future research directions, IEEE Access source

      Not checked in the free run.

    • cites [310] Hossain, 2017, Emotion-aware connected healthcare big data towards 5G, IEEE Internet Things J. source

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Rapid delivery of vaccinations, treatments, and supplies to the point of infection might end outbreaks of potentially fatal infectious illnesses.

    “Rapid delivery of vaccinations, treatments, and supplies to the point of infection might end outbreaks of potentially fatal infectious illnesses.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [318][319][320]

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Drones provide for the delivery of blood, vaccinations, birth control, snakebite serum, and other medical supplies to remote regions and the capacity to reach victims in need of rapid medical treatment within minutes.

    “Drones provide for the delivery of blood, vaccinations, birth control, snakebite serum, and other medical supplies to remote regions and the capacity to reach victims in need of rapid medical treatment within minutes.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [329][330][331]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisereasoning

    Because data breaches in health care have a significant financial impact, health informatics and other experts play a vital role in ensuring that medical organisations stay safe.

    “Because data breaches in health care have a significant financial impact, health informatics and other experts play a vital role in ensuring that medical organisations stay safe.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [347][348][349][350]

      Not checked in the free run.

    • Rests on an assumption: Data breaches in health care have a significant financial impact.
  • May combine two claims.

    Premisecitation

    Blockchain increases a drug's traceability as it passes through the supply chain and aids in the prevention of drug counterfeiting.

    “It increases a drug's traceability as it passes through the supply chain and aids in the prevention of drug counterfeiting.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [360] Siyal, 2019, Applications of blockchain technology in medicine and healthcare: challenges and future perspectives, Cryptography source

      Not checked in the free run.

    • cites [361] Aich, 2022, Protecting personal healthcare record using blockchain & federated learning technologies

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    Blockchain technology can secure data integrity and enable collaboration among increasing healthcare trends.

    “This technology can secure data integrity and enable collaboration among increasing healthcare trends [358,359].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [358] Chelladurai, 2022, A novel blockchain-based electronic health record automation system for healthcare, J. Ambient Intell. Hum. Comput. source

      Not checked in the free run.

    • cites [359] Hölbl, 2018, A systematic review of the use of blockchain in healthcare, Symmetry source

      Not checked in the free run.

  • May combine two claims.

    Premisecitation

    A smartphone health app can alert potentially unsafe situations and suggest behavioural changes that might result in a more positive and desirable outcome.

    “The app can alert potentially unsafe situations and suggest behavioural changes that might result in a more positive and desirable outcome [344,346].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [344] Javaid, 2021, Internet of behaviours (IoB) and its role in customer services, Sens. Int. source

      Not checked in the free run.

    • cites [346] Hampshire, 2021, Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom, Nat. Commun.

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Cybercriminals use malware and ransomware to take down individual devices, servers, or whole networks.

    “Cybercriminals use malware and ransomware to take down individual devices, servers, or whole networks.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [347][348][349][350]

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Blockchain technology can accelerate innovation in preventative care and community-based healthcare solutions.

    “Blockchain technology can accelerate innovation in preventative care and community-based healthcare solutions.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [358] Chelladurai, 2022, A novel blockchain-based electronic health record automation system for healthcare, J. Ambient Intell. Hum. Comput. source

      Not checked in the free run.

    • cites [359] Hölbl, 2018, A systematic review of the use of blockchain in healthcare, Symmetry source

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).

    Premisecitation

    The IoB can become a potent marketing and sales tool for businesses and organisations.

    “The IoB can become a potent marketing and sales tool for businesses and organisations [344,345].”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [344] Javaid, 2021, Internet of behaviours (IoB) and its role in customer services, Sens. Int. source

      Not checked in the free run.

    • cites [345] Bakhshi, 2019, Securing Internet of bio-Nano things: ML-enabled parameter profiling of bio-cyber interfaces

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Companies that have gotten to know us through IoT data may now influence our behaviour with IoB data.

    “Companies that have gotten to know us through IoT data may now influence our behaviour with IoB data.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites [344] Javaid, 2021, Internet of behaviours (IoB) and its role in customer services, Sens. Int. source

      Not checked in the free run.

    • cites [346] Hampshire, 2021, Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom, Nat. Commun.

      Not checked in the free run.

  • Probably not a substantial claim: may not pass S4 (based).

    Interpretationnone given

    Medical 4.0 technologies can bring obstacles, particularly in successfully utilising the rich insights gathered to enhance healthcare outcomes.

    “Medical 4.0 technologies can bring obstacles, particularly in successfully utilising the rich insights gathered to enhance healthcare outcomes.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: Medical 4.0 is still in its early stages, and we may not have a comprehensive picture.
  • Probably not a substantial claim: may not pass S4 (based).

    Interpretationnone given

    Medical 4.0 technologies are considerably altering our interactions with medical devices.

    “These technologies are considerably altering our interactions with medical devices.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S4 (based).

    Interpretationnone given

    Online education for healthcare professionals has decreased the need to travel large distances and spend time away from their jobs.

    “Online education for healthcare professionals has decreased the need to travel large distances and spend time away from their jobs.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationnone given

    Artificial intelligence can assist in identifying viral fragments with the qualities required to achieve various objectives.

    “Artificial intelligence can assist in identifying viral fragments with the qualities required to achieve various objectives.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Interpretationreasoning

    The ongoing COVID-19 pandemic has resulted in a change away from the old paradigm and toward a more dynamic one in which healthcare staff may treat patients remotely.

    “This, combined with the ongoing COVID-19 pandemic, has resulted in a change away from the old paradigm and toward a more dynamic one in which healthcare staff may treat patients remotely.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    Machine learning allows breakthroughs that humans would not otherwise be able to attain.

    “Machine learning allows breakthroughs that humans would not otherwise be able to attain.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationreasoning

    VR can considerably aid healthcare practitioners in their delivery of care.

    “VR can considerably aid healthcare practitioners in their delivery of care.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S4 (based). May combine two claims.

    Interpretationnone given

    Patient-centred AI improves results, costs, and experiences.

    “Patient-centred AI improves results, costs, and experiences.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S4 (based).

    Interpretationnone given

    Allowing patients to participate in their treatment will offer clinicians a wealth of information.

    “Allowing patients to participate in their treatment will offer clinicians a wealth of information.”
    Quote in the paperNot a substantial claim
86 of 86
  • The paper relies on this without support.

    There is an enormous need for improved healthcare for older populations due to expanding and higher life expectancies.

    “Expanding and with higher life expectancies, there is an enormous need for improved healthcare for older populations.”
  • The paper relies on this without support.

    Patients can entrust sensitive personal information to healthcare professionals.

    “Patients can entrust sensitive personal information to healthcare professionals.”
  • The paper relies on this without support.

    Most healthcare providers have begun growing to produce to give fresh meals and have eliminated as many items as feasible.

    “Most healthcare providers have begun growing to produce to give fresh meals and have eliminated as many items as feasible.”
  • The paper relies on this without support.

    Combining wearable monitors with other data sensor sources saves money and time and allows older patients and others with long-term health concerns to effectively track their progress and difficulties.

    “They save money and time by combining wearable monitors with other data sensor sources, allowing older patients and others with long-term health concerns to effectively track their progress and difficulties.”
  • The paper relies on this without support.

    Smart monitoring can aid in detecting early symptoms of illness, resulting in better treatment approaches and prevention.

    “Smart monitoring can aid in detecting early symptoms of illness, resulting in better treatment approaches and prevention.”
  • The paper relies on this without support.

    The most significant advantage of AI and healthcare technology is that they offer correct findings more quickly.

    “The most significant advantage of AI and healthcare technology is that they offer correct findings more quickly.”
  • The paper relies on this without support.

    Data science is critical in monitoring patients' health and informing essential measures to avoid potential illnesses.

    “Data Science is critical in monitoring patients' health and informing essential measures to be made to avoid potential illnesses from occurring.”
  • The paper relies on this without support.

    Smartphone applications enrich human lives by managing personal and professional relationships and activities practically, engagingly, and dynamically.

    “Smartphone applications enrich human lives by managing personal/ professional relationships/activities practically, engaging, and dynamic.”
  • The paper relies on this without support.

    The demand for efficient regeneration therapies is increasing due to the large ageing population, environmental concerns, rising lifestyle problems such as stress, obesity, and diabetes, as well as an increase in trauma cases.

    “The demand for efficient regeneration therapies is increasing due to the large ageing population, environmental concerns, rising lifestyle problems such as stress, obesity, and diabetes, as well as an increase in trauma cases.”
  • The paper relies on this without support.

    The existing healthcare digital infrastructure does not entirely support the essentially necessary security or interoperability.

    “The existing system does not entirely support the essentially necessary security or interoperability.”
  • The paper relies on this without support.

    Data breaches in health care have a significant financial impact.

    “Because data breaches in health care have a significant financial impact”
  • The paper relies on this without support.

    Protected health information is among individuals' most sensitive private data.

    “Because protected health information is among individuals' most sensitive private data”
  • The paper relies on this without support.

    Medical 4.0 is still in its early stages, and we may not have a comprehensive picture.

    “Indeed, Medical 4.0 is still in its early stages, and we may not have a comprehensive picture.”
13 of 13

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Telemedicine and telehealth are defined both as equivalent and as distinct

    Minor

    Section 8.1 presents telehealth as another name for telemedicine, then says telehealth is broader and includes non-clinical services. Those definitions do not describe the same scope.

1 of 1

Cites

Flagged first, then by citations

28 of the 411 references couldn’t be matched to a known paper.

Research works printed but not linked: 8

  1. Wu, 2019, Wearable technology applications in healthcare: a literature review, Online J. Nurs. Inform., 23
  2. Kulkarni, 2014, Healthcare applications of the internet of things: a review, Int. J. Comput. Sci. Inf. Technol., 5, 6229
  3. Azzawi, 2016, A review on internet of things (IoT) in healthcare, Int. J. Appl. Eng. Res., 11, 10216
  4. Srivastava, 2018, Self-organised design of virtual reality simulator for identification and optimization of healthcare software components, J. Ambient Intell. Hum. Comput., 1
  5. Kumar, 2018, Healthcare solution based on machine learning applications in IOT and edge computing, Int. J. Pure Appl. Math., 119, 1473
  6. Ransikabum, 2019, Additive manufacturing-based healthcare 3D model for education: literature review and A feasibility study, 1
  7. Pathak, 2019, Humanitarian impact of drones in healthcare and disaster management, Int. J. Recent Technol. Eng., 7, 201
  8. Tanwar, 2020, Blockchain-based electronic healthcare record system for healthcare 4.0 applications, J. Inf. Secur. Appl., 50

Cited by

Sorted by citations

Authors
Haleem, A., Javaid, M., Pratap Singh, R., & Suman, R.
Affiliations
  • Jamia Millia Islamia (IN)
  • Govind Ballabh Pant University of Agriculture and Technology (IN)
Corresponding author
Javaid, Mohd
Venue
Internet of Things and Cyber-Physical Systems
Publisher
Elsevier BV
Published
2022
Volume
2
Pages
12-30
ISSN
2667-3452 (ISSN-L)
OpenAlex
W4224055696
Cited by
468
References
411
Citations by year
2026: 53 · 2025: 211 · 2024: 119 · 2023: 76 · 2022: 8
FWCI
102.48
Type
journal article
Language
en
Open access
Locations
  • Internet of Things and Cyber-Physical Systems (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Physical Sciences › Computer Science › Information Systems › Internet of Things and AI
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
  • Physical Sciences › Engineering › Industrial and Manufacturing Engineering › Digital Transformation in Industry
Keywords
Fourth Industrial Revolution, Internet of Things, digitalization of healthcare, patient-centered care, cloud computing, mobile computing, patient information, health care access, new medical technologies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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