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Bioactive Coatings Based on a Polyelectrolyte Multilayer Architecture Functionalized by Embedded Proteins
Abstract
Does a signal protein imbedded in a polyelectrolyte layer keep its activity? The study reported here demonstrates that cells can indeed interact with proteins incorporated in poly(L‐lysine/glutamic acid) multilayer films. In contrast, poly(D‐lysine) acts as a barrier to cell communication. For the case of monocytic cells the mechanism of contact with the active protein is elucidated. It is believed that such functionalized coatings could be useful tools for the modification of biomaterial surfaces with applications in, e.g., implants or tissue engineering.
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Cited by
Biomedical Applications of Layer‐by‐Layer Assembly: From Biomimetics to Tissue Engineering
Tang, Z., Wang, Y., Podsiadlo, P., & Kotov, N. A. (2006) · Advanced Materials · doi:10.1002/adma.200600113 · Cited by 1,302
Richert, L., Boulmedais, F., Lavalle, P., Mutterer, J., Ferreux, E., Decher, G., Schaaf, P., Voegel, J.-C., & Picart, C. (2004) · Biomacromolecules · doi:10.1021/bm0342281 · Cited by 437
Self-citationShi, F., Wang, Z., & Zhang, X. (2005) · Advanced Materials · doi:10.1002/adma.200402090 · Cited by 344
Mahmoudi, M., Simchi, A., Imani, M., Shokrgozar, M. A., Milani, A. S., Häfeli, U. O., & Stroeve, P. (2010) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2009.08.044 · Cited by 294
Wood, K. C., Chuang, H. F., Batten, R. D., Lynn, D. M., & Hammond, P. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602884103 · Cited by 270
Metadata
- Authors
- Jessel, N., Atalar, F., Lavalle, P., Mutterer, J., Decher, G., Schaaf, P., Voegel, J. ‐., & Ogier, J.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2003-04-25
- Volume
- 15
- Issue
- 9
- Pages
- 692-695
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2059473135
- Cited by
- 242
- References
- 0
- FWCI
- 18.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jessel, N., Atalar, F., Lavalle, P., Mutterer, J., Decher, G., Schaaf, P., Voegel, J. ‐., & Ogier, J. (2003). Bioactive Coatings Based on a Polyelectrolyte Multilayer Architecture Functionalized by Embedded Proteins. Advanced Materials. https://doi.org/10.1002/adma.200304634
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
