The Use of Functionalized Silk Fibroin Films as a Platform for Optical Diffraction‐Based Sensing Applications
Abstract
A set of biocompatible, biodegradable, and biofunctionalizable diffractive optical elements (DOEs) using silk proteins as the building materials is reported. The diffraction pattern of a DOE is highly sensitive to the surrounding environment and the structural integrity, offering numerous opportunities for biosensing applications.
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In vivo animal models possess limitations: species-specific differences between animals and humans cause differences in drug efficacy and toxicity tests in physiology and cell biology.
“Species-specific differences between animals and humans cause differences in drug efficacy and toxicity tests in physiology and cell biology31–37.”
From Tumor-on-a-chip: from bioinspired design to biomedical application (2021) · cites this paper as [37]
Cites
Materials fabrication from Bombyx mori silk fibroin
Rockwood, D. N., Preda, R. C., Yücel, T., Wang, X., Lovett, M. L., & Kaplan, D. L. (2011) · Nature Protocols · doi:10.1038/nprot.2011.379 · Cited by 3,096 · see citing works
Self-citationBiodegradation of Silk Biomaterials
Cao, Y., & Wang, B. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10041514 · Cited by 719 · see citing works
Silk Materials – A Road to Sustainable High Technology
Tao, H., Kaplan, D. L., & Omenetto, F. G. (2012) · Advanced Materials · doi:10.1002/adma.201104477 · Cited by 528 · see citing works
Self-citationOmenetto, F. G., & Kaplan, D. L. (2008) · Nature Photonics · doi:10.1038/nphoton.2008.207 · Cited by 333 · see citing works
Self-citationFabrication of Silk Microneedles for Controlled‐Release Drug Delivery
Tsioris, K., Raja, W. K., Pritchard, E. M., et al. (2011) · Advanced Functional Materials · doi:10.1002/adfm.201102012 · Cited by 300 · see citing works
Progress of new label-free techniques for biosensors: a review
Sang, S., Wang, Y., Feng, Q., Wei, Y., Ji, J., & Zhang, W. (2015) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2014.991270 · Cited by 276 · see citing works
Weissleder, R., & Nahrendorf, M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1508524112 · Cited by 216 · see citing works
Antibiotic‐Releasing Silk Biomaterials for Infection Prevention and Treatment
Pritchard, E. M., Valentin, T., Panilaitis, B., Omenetto, F. G., & Kaplan, D. L. (2012) · Advanced Functional Materials · doi:10.1002/adfm.201201636 · Cited by 191 · see citing works
Self-citationPhysical and chemical aspects of stabilization of compounds in silk
Pritchard, E. M., Dennis, P. B., Omenetto, F. G., Naik, R. R., & Kaplan, D. L. (2012) · Biopolymers · doi:10.1002/bip.22026 · Cited by 155 · see citing works
Self-citationImplantable, multifunctional, bioresorbable optics
Tao, H., Kainerstorfer, J. M., Siebert, S. M., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209056109 · Cited by 119 · see citing works
Effect of Silk Protein Processing on Drug Delivery from Silk Films
Pritchard, E. M., Hu, X., Finley, V., Kuo, C. K., & Kaplan, D. L. (2013) · Macromolecular Bioscience · doi:10.1002/mabi.201200323 · Cited by 105 · see citing works
Self-citationImmobilization of antibodies in micropatterns for cell detection by optical diffraction
Morhard, F., Pipper, J., Dahint, R., et al. (2000) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(00)00574-8 · Cited by 71 · see citing works
Porous silicon structures for low-cost diffraction-based biosensing
Ryckman, J. D., Liscidini, M., Sipe, J. E., et al. (2010) · Applied Physics Letters · doi:10.1063/1.3421545 · Cited by 62 · see citing works
Biopatterning of Silk Proteins for Soft Micro-optics
Pal, R. K., Kurland, N. E., Wang, C., Kundu, S. C., & Yadavalli, V. K. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b01380 · Cited by 55 · see citing works
Flexible, fast, and low-cost production process for polymer based diffractive optics
Rahlves, M., Rezem, M., Boroz, K., et al. (2015) · Optics Express · doi:10.1364/oe.23.003614 · Cited by 48 · see citing works
Cashmere-derived keratin for device manufacturing on the micro- and nanoscale
Marelli, B., & Omenetto, F. G. (2015) · Journal of Materials Chemistry C · doi:10.1039/c5tc00056d · Cited by 27 · see citing works
Self-citationBiodegradation behavior of silk biomaterials
Li, M., & Li, J. (2014) · Elsevier eBooks · doi:10.1533/9780857097064.2.330 · Cited by 25 · see citing works
Diffractive Optical Analysis for Refractive Index Sensing using Transparent Phase Gratings
Kumawat, N., Pal, P., & Varma, M. M. (2015) · Scientific Reports · doi:10.1038/srep16687 · Cited by 23 · see citing works
Optofluidics for Biophotonic Applications
Bragheri, F., Osellame, R., & Ramponi, R. (2012) · IEEE photonics journal · doi:10.1109/jphot.2012.2190725 · Cited by 6 · see citing works
Schwiegerling, J. T. (2011) · Series in optics and optoelectronics · doi:10.1201/b10863-3 · Cited by 1 · see citing works
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Tumor-on-a-chip: from bioinspired design to biomedical application
Liu, X., Fang, J., Huang, S., Wu, X., Xie, X., Wang, J., Liu, F., Zhang, M., Peng, Z., & Hu, N. (2021) · Microsystems & Nanoengineering · doi:10.1038/s41378-021-00277-8 · Cited by 246 · see citing works
Khoshmanesh, F., Thurgood, P., Pirogova, E., Nahavandi, S., & Baratchi, S. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112946 · Cited by 204 · see citing works
Zhang, S., Zhou, Z., Zhong, J., Shi, Z., Mao, Y., & Tao, T. H. (2020) · Advanced Science · doi:10.1002/advs.201903802 · Cited by 120 · see citing works
Self-citation
- Authors
- Zhou, Z., Shi, Z., Cai, X., Zhang, S., Corder, S. G., Li, X., Zhang, Y., Zhang, G., Chen, L., Liu, M., Kaplan, D. L., Omenetto, F. G., Mao, Y., Tao, Z., & Tao, T. H.
- Affiliations
- Chinese Academy of Sciences (CN)
- Shanghai Medical College of Fudan University (CN)
- The University of Texas at Austin (US)
- Department of Physics and Astronomy Stony Brook University Stony Brook NY 11794 USA
- Jiangsu University of Science and Technology (CN)
- Stony Brook University (US)
- Tufts University (US)
- Second Hospital of Nanchang (CN)
- Corresponding author
- Tao, Zhendong
- Tao, Tiger H.
- ORCID
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2017-02-13
- Volume
- 29
- Issue
- 15
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2588839040
- Cited by
- 148
- References
- 20
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 8 · 2023: 15 · 2022: 22 · 2021: 20 · 2020: 20 · 2019: 22 · 2018: 24 · 2017: 7
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Advanced Materials (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (61574156, 61527818)
- Ministry of Science and Technology of the People's Republic of China (2016YFA0200800)
- Natural Science Foundation of Jiangsu Province (BK20160554)
- Science and Technology Commission of Shanghai Municipality
- Natural Science Foundation of Shanghai (16JC1420100)
- Directorate for Engineering (1563422, 1562915)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced Fiber Optic Sensors
- Keywords
- silk fibroin, diffractive optical elements, light diffraction, biosensing, biodegradable materials, biomaterials, biofunctionalization
- MeSH terms
- Animals, Biocompatible Materials, Fibroins, Bombyx, Silk, Optical Devices
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