The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
DNA Hydrogels and Microgels for Biosensing and Biomedical Applications
Abstract
DNA hydrogels, which take advantage of the unique properties of functional DNA motifs, such as specific molecular recognition, programmable and high‐precision assembly, multifunctionality, and excellent biocompatibility, have attracted increasing research interest in the past two decades in diverse fields, especially in biosensing and biomedical applications. The responsiveness of smart DNA hydrogels to external stimuli by changing their swelling volume, crosslinking density, and optical or mechanical properties has facilitated the development of DNA‐hydrogel‐based in vitro biosensing systems and actuators. Furthermore, reducing the sizes of DNA hydrogels to the micro‐ and nanoscale leads to better responsiveness and delivery capacity, thereby making them excellent candidates for rapid detection, in vivo real‐time sensing, and drug release applications. Here, the recent progress in the development of smart DNA hydrogels and DNA microgels for biosensing and biomedical applications is summarized, and the current challenges as well as future prospects are also discussed.
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Cites
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Lu, P., Ruan, D., Huang, M., Tian, M., Zhu, K., Gan, Z., & Xiao, Z. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01852-x · Cited by 667
Zhang, K., Feng, Q., Fang, Z., Gu, L., & Bian, L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00071 · Cited by 394
DNA hydrogel-based gene editing and drug delivery systems
Mo, F., Jiang, K., Zhao, D., Wang, Y., Song, J., & Tan, W. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.07.018 · Cited by 304
Metadata
- Authors
- Li, F., Lyu, D., Liu, S., & Guo, W.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2019-08-05
- Volume
- 32
- Issue
- 3
- Pages
- e1806538-e1806538
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2964974813
- Cited by
- 305
- References
- 89
- FWCI
- 9.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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