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MOFBOTS: Metal–Organic‐Framework‐Based Biomedical Microrobots
Open accessAbstract
Motile metal−organic frameworks (MOFs) are potential candidates to serve as small‐scale robotic platforms for applications in environmental remediation, targeted drug delivery, or nanosurgery. Here, magnetic helical microstructures coated with a kind of zinc‐based MOF, zeolitic imidazole framework‐8 (ZIF‐8), with biocompatibility characteristics and pH‐responsive features, are successfully fabricated. Moreover, it is shown that this highly integrated multifunctional device can swim along predesigned tracks under the control of weak rotational magnetic fields. The proposed systems can achieve single‐cell targeting in a cell culture media and a controlled delivery of cargo payloads inside a complex microfluidic channel network. This new approach toward the fabrication of integrated multifunctional systems will open new avenues in soft microrobotics beyond current applications.
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Cited by
Metal-organic frameworks for advanced drug delivery
He, S., Wu, L., Li, X., Sun, H., Xiong, T., Liu, J., Huang, C., Xu, H., Sun, H., Chen, W., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.019 · Cited by 528
3D printing of functional microrobots
Li, J., & Pumera, M. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01062f · Cited by 303
Liu, L., Chen, B., Liu, K., Gao, J., Ye, Y., Wang, Z., Qin, N., Wilson, D. A., Tu, Y., & Peng, F. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910108 · Cited by 150
Metadata
- Authors
- Wang, X., Chen, X., Alcântara, C. C. J., Sevim, S., Hoop, M., Terzopoulou, A., de Marco, C., Hu, C., de Mello, A. J., Falcaro, P., Furukawa, S., Nelson, B. J., Puigmartí‐Luis, J., & Pané, S.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2019-05-06
- Volume
- 31
- Issue
- 27
- Pages
- e1901592-e1901592
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2944519259
- Cited by
- 228
- References
- 0
- FWCI
- 15.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, X., Chen, X., Alcântara, C. C. J., Sevim, S., Hoop, M., Terzopoulou, A., de Marco, C., Hu, C., de Mello, A. J., Falcaro, P., Furukawa, S., Nelson, B. J., Puigmartí‐Luis, J., & Pané, S. (2019). MOFBOTS: Metal–Organic‐Framework‐Based Biomedical Microrobots. Advanced Materials. https://doi.org/10.1002/adma.201901592
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