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Cited by 304

The DOI matches its Crossref record; 155 of the 155 references it cites were found in a registry or an index.

Bacteria‐Based Cancer Immunotherapy

Open access
Huang, Xuehui, Pan, Jingmei, Xu, Funeng, Shao, Binfen, Wang, Yi, Guo, Xing, Zhou, Shaobing·2021·Advanced Science

Abstract

In the past decade, bacteria‐based cancer immunotherapy has attracted much attention in the academic circle due to its unique mechanism and abundant applications in triggering the host anti‐tumor immunity. One advantage of bacteria lies in their capability in targeting tumors and preferentially colonizing the core area of the tumor. Because bacteria are abundant in pathogen‐associated molecular patterns that can effectively activate the immune cells even in the tumor immunosuppressive microenvironment, they are capable of enhancing the specific immune recognition and elimination of tumor cells. More attractively, during the rapid development of synthetic biology, using gene technology to enable bacteria to be an efficient producer of immunotherapeutic agents has led to many creative immunotherapy paradigms. The combination of bacteria and nanomaterials also displays infinite imagination in the multifunctional endowment for cancer immunotherapy. The current progress report summarizes the recent advances in bacteria‐based cancer immunotherapy with specific foci on the applications of naive bacteria‐, engineered bacteria‐, and bacterial components‐based cancer immunotherapy, and at the same time discusses future directions in this field of research based on the present developments.

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Metadata

Authors
Huang, X., Pan, J., Xu, F., Shao, B., Wang, Y., Guo, X., & Zhou, S.
Venue
Advanced Science
Publisher
Wiley
Published
2021-02-10
Volume
8
Issue
7
Pages
2003572-2003572
ISSN
2198-3844 (ISSN-L)
OpenAlex
W3127650252
Cited by
304
References
155
FWCI
22.57
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Bacteria‐Based Cancer Immunotherapy. https://app.cochat.ai/papers/10.1002/advs.202003572
The paper
Huang, X., Pan, J., Xu, F., Shao, B., Wang, Y., Guo, X., & Zhou, S. (2021). Bacteria‐Based Cancer Immunotherapy. Advanced Science. https://doi.org/10.1002/advs.202003572

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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