The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
TEG and ROTEM: Technology and clinical applications
Open accessAbstract
Initially described in 1948 by Hertert thromboelastography (TEG) provides a real‐time assessment of viscoelastic clot strength in whole blood. Rotational thromboelastometry (ROTEM) evolved from TEG technology and both devices generate output by transducing changes in the viscoelastic strength of a small sample of clotting blood (300 µl) to which a constant rotational force is applied. These point of care devices allow visual assessment of blood coagulation from clot formation, through propagation, and stabilization, until clot dissolution. Computer analysis of the output allows sophisticated clot formation/dissolution kinetics and clot strength data to be generated. Activation of clot formation can be initiated with both intrinsic (kaolin, ellagic acid) and extrinsic (tissue factor) activators. In addition, the independent contributions of platelets and fibrinogen to final clot strength can be assessed using added platelet inhibitors (abciximab and cytochalasin D). Increasingly, ROTEM and TEG analysis is being incorporated in vertical algorithms to diagnose and treat bleeding in high‐risk populations such as those undergoing cardiac surgery or suffering from blunt trauma. Some evidence suggests these algorithms might reduce transfusions, but further study is needed to assess patient outcomes. Am. J. Hematol. 89:228–232, 2014. © 2013 Wiley Periodicals, Inc.
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Cites
Thromboelastography-Guided Transfusion Algorithm Reduces Transfusions in Complex Cardiac Surgery
Shore-Lesserson, L., Manspeizer, H. E., DePerio, M., Francis, S., Vela-Cantos, F., & Ergin, M. A. (1999) · Anesthesia & Analgesia · doi:10.1097/00000539-199902000-00016 · Cited by 845
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Weber, C. F., Görlinger, K., Meininger, D., Herrmann, E., Bingold, T., Moritz, A., Cohn, L. H., & Zacharowski, K. (2012) · Anesthesiology · doi:10.1097/aln.0b013e318264c644 · Cited by 625
Blutgerinnungsstudien mit der Thrombelastographie, einem neuen Untersuchungsverfahren
Hartert, H. (1948) · Klinische Wochenschrift · doi:10.1007/bf01697545 · Cited by 615
Functional definition and characterization of acute traumatic coagulopathy
Davenport, R., Manson, J., DeʼAth, H., Platton, S., Coates, A., Allard, S., Hart, D., Pearse, R., Pasi, K. J., MacCallum, P., et al. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182281af5 · Cited by 520
The incidence and magnitude of fibrinolytic activation in trauma patients
RAZA, I., DAVENPORT, R., ROURKE, C., PLATTON, S., MANSON, J., SPOORS, C., KHAN, S., De'ATH, H. D., ALLARD, S., HART, D. P., et al. (2013) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12078 · Cited by 481
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Cited by
Extracorporeal Membrane Oxygenation—Hemostatic Complications
Murphy, D. A., Hockings, L. E., Andrews, R. K., Aubron, C., Gardiner, E. E., Pellegrino, V. A., & Davis, A. K. (2015) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2014.12.001 · Cited by 455
Point-of-care viscoelastic tests in the management of obstetric hemorrhage
Nelson, D. B., Ogunkua, O., & Cunningham, F. G. (2022) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000004686 · Cited by 13
Metadata
- Authors
- Whiting, D., & DiNardo, J. A.
- Venue
- American Journal of Hematology
- Publisher
- Wiley
- Published
- 2014-02
- Volume
- 89
- Issue
- 2
- Pages
- 228-232
- ISSN
- 0361-8609 (ISSN-L)
- 1096-8652
- OpenAlex
- W1524658408
- Cited by
- 688
- References
- 27
- FWCI
- 20.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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