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Cited by 37Morphological variations and asymmetryForensic Anthropology and Bioarchaeology StudiesGenetic diversity and population structure

Genomic validation of the differential preservation of population history in modern human cranial anatomy

Reyes‐Centeno, Hugo, Ghirotto, Silvia, Harvati, Katerina·2017·American Journal of Physical Anthropology
DOI 10.1002/ajpa.23060
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Abstract

Objectives: In modern humans, the significant correlation between neutral genetic loci and cranial anatomy suggests that the cranium preserves a population history signature. However, there is disagreement on whether certain parts of the cranium preserve this signature to a greater degree than other parts. It is also unclear how different quantitative measures of phenotype affect the association of genetic variation and anatomy. Here, we revisit these matters by testing the correlation of genetic distances and various phenotypic distances for ten modern human populations. Materials and Methods: Geometric morphometric shape data from the crania of adult individuals (n = 224) are used to calculate phenotypic PST, Procrustes, and Mahalanobis distances. We calculate their correlation to neutral genetic distances, FST, derived from single nucleotide polymorphisms (SNPs). We subset the cranial data into landmark configurations that include the neurocranium, the face, and the temporal bone in order to evaluate whether these cranial regions are differentially correlated to neutral genetic variation. Results: Our results show that PST, Mahalanobis, and Procrustes distances are correlated with FST distances to varying degrees. They indicate that overall cranial shape is significantly correlated with neutral genetic variation. Of the component parts examined, PST distances for both the temporal bone and the face have a stronger association with FST distances than the neurocranium. When controlling for population divergence time, only the whole cranium and the temporal bone have a statistically significant association with FST distances. Discussion: Our results confirm that the cranium, as a whole, and the temporal bone can be used to reconstruct modern human population history.

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  • While facial morphology carries a neutral genetic or population history signal, it is more strongly affected by climatic conditions than other parts of the cranium, especially in high latitude populations.

    “while facial morphology does carry a neutral genetic or population history signal, it is more strongly affected by climatic conditions than other parts of the cranium, especially in high latitude populations 81,82,83”

    From The evolutionary history of the human face (2019) · cites this paper as [83]

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Authors
Reyes‐Centeno, H., Ghirotto, S., & Harvati, K.
Affiliations
  • Senckenberg Centre for Human Evolution and Palaeoenvironment (DE)
  • University of Ferrara (IT)
Corresponding author
Reyes‐Centeno, Hugo
ORCID
Venue
American Journal of Physical Anthropology
Publisher
Wiley
Published
2016-08-04
Volume
162
Issue
1
Pages
170-179
ISSN
  • 0002-9483 (ISSN-L)
  • 1096-8644
DOI
10.1002/ajpa.23060
OpenAlex
W2493489323
Cited by
37
References
68
Citations by year
2026: 2 · 2025: 3 · 2023: 4 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 7 · 2018: 3 · 2017: 6 · 2016: 1
FWCI
8.13
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • American Journal of Physical Anthropology (publishedVersion)
  • PubMed (publishedVersion)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
Funders
Deutsche Forschungsgemeinschaft (DFG FOR 2237)
Topics
  • Physical Sciences › Mathematics › Geometry and Topology › Morphological variations and asymmetry
  • Social Sciences › Arts and Humanities › Archeology › Forensic Anthropology and Bioarchaeology Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
Keywords
skull morphology, demographic history, genetic distance, head shape, temporal bone, face, neurocranium, FST, single nucleotide polymorphisms, geometric morphometrics, population divergence time
MeSH terms
Adult, Anthropology, Physical, Cephalometry, Female, Genetics, Population, Humans, Male, Skull, Reproducibility of Results, Polymorphism, Single Nucleotide, Genomics

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