The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Amantadine use associated with impulse control disorders in Parkinson disease in cross‐sectional study
Abstract
A recent controlled clinical trial suggested a role for amantadine as a treatment for pathological gambling in patients with Parkinson disease (PD). Analyzing data from a large cross‐sectional study of impulse control disorders (ICDs) in PD, amantadine use (n = 728), vs no amantadine use (n = 2,357), was positively associated with a diagnosis of any ICD (17.6% vs 12.4%, p < 0.001) and compulsive gambling specifically (7.4% vs 4.2%, p < 0.001). This amantadine association remained after controlling for covariates of amantadine use, including both dopamine agonist use and levodopa dosage. Further research, including larger clinical trials, is needed to assess the role of amantadine in the development and treatment of ICDs in PD. Ann Neurol 2010
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Association of dopamine agonist use with impulse control disorders in Parkinson disease
Weintraub, D., Siderowf, A. D., Potenza, M. N., Goveas, J., Morales, K. H., Duda, J. E., Moberg, P. J., & Stern, M. B. (2006) · Archives of Neurology · doi:10.1001/archneur.63.7.969 · Cited by 662 · cited 1×
“Regarding preliminary evidence for the relationship between amantadine use and ICDs in PD, in a previous study amantadine treatment was associated with the presence of an ICD on univariate analysis, but not in a multivariable model.(19) However, the sample size in that study was nearly 10-fold lower than in this study…”
ResultSelf-citationPathological Gambling Caused by Drugs Used to Treat Parkinson Disease
Dodd, M. L., Klos, K. J., Bower, J. H., Geda, Y. E., Josephs, K. A., & Ahlskog, J. E. (2005) · Archives of Neurology · doi:10.1001/archneur.62.9.noc50009 · Cited by 563
Cited by
Seppi, K., Weintraub, D., Coelho, M., Perez‐Lloret, S., Fox, S. H., Katzenschlager, R., Hametner, E., Poewe, W., Rascol, O., Goetz, C. G., et al. (2011) · Movement Disorders · doi:10.1002/mds.23884 · Cited by 1,141
Self-citationImpulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update
Voon, V., Napier, T. C., Frank, M. J., Sgambato-Faure, V., Grace, A. A., Rodriguez-Oroz, M., Obeso, J., Bezard, E., & Fernagut, P.-O. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30004-2 · Cited by 359
Self-citationClinical spectrum of impulse control disorders in Parkinson’s disease
Weintraub, D., David, A. S., Evans, A. H., Grant, J. E., & Stacy, M. (2015) · Movement Disorders · doi:10.1002/mds.26016 · Cited by 311
Self-citationTrial of CBT for impulse control behaviors affecting Parkinson patients and their caregivers
Okai, D., Askey-Jones, S., Samuel, M., O’Sullivan, S. S., Chaudhuri, K. R., Martin, A., Mack, J., Brown, R. G., & David, A. S. (2013) · Neurology · doi:10.1212/wnl.0b013e3182840678 · Cited by 202
A systematic review of impulse control disorders in Parkinson’s disease.
Callesen, M. B., Scheel-Krüger, J., Kringelbach, M. L., & Møller, A. (2013) · Journal of Parkinson s Disease · doi:10.3233/jpd-120165 · Cited by 130
Metadata
- Authors
- Weintraub, D., Sohr, M., Potenza, M. N., Siderowf, A. D., Stacy, M., Voon, V., Whetteckey, J., Wunderlich, G. R., & Lang, A. E.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2010-12
- Volume
- 68
- Issue
- 6
- Pages
- 963-968
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2101307138
- Cited by
- 158
- References
- 2
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Amantadine use associated with impulse control disorders in Parkinson disease in cross‐sectional study. https://app.cochat.ai/papers/10.1002/ana.22164
- The paper
- Weintraub, D., Sohr, M., Potenza, M. N., Siderowf, A. D., Stacy, M., Voon, V., Whetteckey, J., Wunderlich, G. R., & Lang, A. E. (2010). Amantadine use associated with impulse control disorders in Parkinson disease in cross‐sectional study. Annals of Neurology. https://doi.org/10.1002/ana.22164
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.