The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
The blood–spinal cord barrier: Morphology and Clinical Implications
Abstract
The blood–spinal cord barrier (BSCB) is the functional equivalent of the blood–brain barrier (BBB) in the sense of providing a specialized microenvironment for the cellular constituents of the spinal cord. Even if intuitively the BSCB could be considered as the morphological extension of the BBB into the spinal cord, evidence suggests that this is not so. The BSCB shares the same principal building blocks with the BBB; nevertheless, it seems that morphological and functional differences may exist between them. Dysfunction of the BSCB plays a fundamental role in the etiology or progression of several pathological conditions of the spinal cord, such as spinal cord injury, amyotrophic lateral sclerosis, and radiation‐induced myelopathy. This review summarizes current knowledge of the morphology of the BSCB, the methodology of studying the BSCB, and the potential role of BSCB dysfunction in selected disorders of the spinal cord, and finally summarizes therapeutic approaches to the BSCB. Ann Neurol 2011;
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Cites
Astrocyte-endothelial interactions at the blood-brain barrier
Abbott, N. J., Rönnbäck, L., & Hansson, E. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1824 · Cited by 5,595
Structure and function of the blood–brain barrier
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Cited by
Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review
Jin, L.-Y., Li, J., Wang, K.-F., Xia, W.-W., Zhu, Z.-Q., Wang, C.-R., Li, X.-F., & Liu, H.-Y. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2020.7413 · Cited by 283
Liu, W.-Z., Ma, Z.-J., Li, J.-R., & Kang, X.-W. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02153-8 · Cited by 252
Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary Permeability
Winkler, E. A., Sengillo, J. D., Bell, R. D., Wang, J., & Zlokovic, B. V. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.113 · Cited by 226
Age- and location-related changes in microglial function
Ritzel, R. M., Patel, A. R., Pan, S., Crapser, J., Hammond, M., Jellison, E., & McCullough, L. D. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.02.016 · Cited by 134
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
Ramirez, S. H., Andrews, A. M., Paul, D., & Pachter, J. S. (2018) · Fluids and Barriers of the CNS · doi:10.1186/s12987-018-0104-7 · Cited by 128
Metadata
- Authors
- Bartanusz, V., Jezova, D., Alajajian, B., & Digicaylioglu, M.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2011-06-14
- Volume
- 70
- Issue
- 2
- Pages
- 194-206
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2120143347
- Cited by
- 481
- References
- 124
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- closed
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