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Cited by 283

The DOI matches its Crossref record; 204 of the 204 references it cites were found in a registry or an index.

Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review

Jin, Lin-Yu, Li, Jie, Wang, Kai-Feng, Xia, Wei-Wei, Zhu, Zhen-Qi, Wang, Chun-Ru, Li, Xin-Feng, Liu, Hai-Ying·2021·Journal of Neurotrauma

Abstract

The blood-spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord and maintains a tightly controlled chemical balance in the spinal environment, which is necessary for proper neural function. A BSCB disruption, however, plays an important role in primary and secondary injury processes related to spinal cord injury (SCI). After SCI, the structure of the BSCB is broken down, which leads directly to leakage of blood components. At the same time, the permeability of the BSCB is also increased. Repairing the disruption of the BSCB could alleviate the SCI pathology. We review the morphology and pathology of the BSCB and progression of therapeutic methods targeting BSCB in SCI.

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Metadata

Authors
Jin, L.-Y., Li, J., Wang, K.-F., Xia, W.-W., Zhu, Z.-Q., Wang, C.-R., Li, X.-F., & Liu, H.-Y.
Venue
Journal of Neurotrauma
Published
2021-05-01
Volume
38
Issue
9
Pages
1203-1224
ISSN
  • 0897-7151 (ISSN-L)
  • 1557-9042
OpenAlex
W3111030686
Cited by
283
References
204
FWCI
13.72
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review. https://app.cochat.ai/papers/10.1089/neu.2020.7413
The paper
Jin, L.-Y., Li, J., Wang, K.-F., Xia, W.-W., Zhu, Z.-Q., Wang, C.-R., Li, X.-F., & Liu, H.-Y. (2021). Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review. Journal of Neurotrauma. https://doi.org/10.1089/neu.2020.7413

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