The DOI matches its Crossref record; 204 of the 204 references it cites were found in a registry or an index.
Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review
Abstract
The blood-spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord and maintains a tightly controlled chemical balance in the spinal environment, which is necessary for proper neural function. A BSCB disruption, however, plays an important role in primary and secondary injury processes related to spinal cord injury (SCI). After SCI, the structure of the BSCB is broken down, which leads directly to leakage of blood components. At the same time, the permeability of the BSCB is also increased. Repairing the disruption of the BSCB could alleviate the SCI pathology. We review the morphology and pathology of the BSCB and progression of therapeutic methods targeting BSCB in SCI.
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Vargas-Rodríguez, P., Cuenca-Martagón, A., Castillo-González, J., Serrano-Martínez, I., Luque, R. M., Delgado, M., & González-Rey, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814117 · Cited by 25
Metadata
- Authors
- Jin, L.-Y., Li, J., Wang, K.-F., Xia, W.-W., Zhu, Z.-Q., Wang, C.-R., Li, X.-F., & Liu, H.-Y.
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2021-05-01
- Volume
- 38
- Issue
- 9
- Pages
- 1203-1224
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W3111030686
- Cited by
- 283
- References
- 204
- FWCI
- 13.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jin, L.-Y., Li, J., Wang, K.-F., Xia, W.-W., Zhu, Z.-Q., Wang, C.-R., Li, X.-F., & Liu, H.-Y. (2021). Blood–Spinal Cord Barrier in Spinal Cord Injury: A Review. Journal of Neurotrauma. https://doi.org/10.1089/neu.2020.7413
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