Much of late life cognitive decline is not due to common neurodegenerative pathologies

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Items 201–300 of 322

  1. An interpretable machine learning‐based cerebrospinal fluid proteomics clock for predicting age reveals novel insights into brain aging
    Justin Melendez, Yun Ju Sung, Miranda E. Orr, Andrew S.J. Yoo, Suzanne E. Schindler, Carlos Cruchaga, Randall John Bateman · 2024 · Aging Cell
  2. Ankle brachial index and cognitive function among Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos
    W. Tarraf, M. Criqui, M. Allison, C. Wright, M. Fornage, M. Daviglus, R. Kaplan, S. Davis, A. Conceicao, H. González · 2018 · Atherosclerosis
  3. Neurodegenerative disease and cognitive retest learning
    Robert S. Wilson, Ana Werneck Capuano, Lei Yu, Jingyun Yang, Namhee Kim, Sue E. Leurgans, Melissa Lamar, Julie A. Schneider, David Alan Bennett, Patricia A. Boyle · 2018 · Neurobiology of Aging
  4. The SNAP25 Interactome in Ventromedial Caudate in Schizophrenia Includes the Mitochondrial Protein ARF1
    Alfredo Ramos‐Miguel, Vilte Barakauskas, Jehan Alamri, Masatoshi Miyauchi, Alasdair M. Barr, Clare L. Beasley, Gorazd B. Rosoklija, Joseph John Mann, Andrew J. Dwork, Annie Moradian et al. · 2019 · Neuroscience
  5. A cortical immune network map identifies a subset of human microglia involved in Tau pathology
    Patrick, Ellis, Olah, Marta, Taga, Mariko, Klein, Hans-Ulrich, Xu, Jishu, White, Charles C, Felsky, Daniel, Gaiteri, Chris, Chibnik, Lori B, Mostafavi, Sara et al. · 2017
  6. Longitudinal Modeling of Functional Decline Associated with Pathologic Alzheimer’s Disease in Older Persons without Cognitive Impairment
    Dai Wang, Tim Schultz, Gerald Novak, Susan A. Baker, David Alan Bennett, Vaibhav A. Narayan · 2018 · Journal of Alzheimer s Disease
  7. The effects of COVID-19 infection on working memory: a systematic review
    Rui Cui, Beiyao Gao, Ruidong Ge, MingZhen Li, Min Li, Xi Lu, Shan Jiang · 2023 · Current Medical Research and Opinion
  8. Mixed Neuropathologies, Neural Motor Resilience and Target Discovery for Therapies of Late-Life Motor Impairment
    Aron S. Buchman, David Alan Bennett · 2022 · Frontiers in Human Neuroscience
  9. Urinary Incontinence, Incident Parkinsonism, and Parkinson’s Disease Pathology in Older Adults
    Noa Buchman, Sue E. Leurgans, Raj J. Shah, Veronique VanderHorst, Robert S. Wilson, Yaacov G. Bachner, David Tanné, Julie A. Schneider, David Alan Bennett, Aron S. Buchman · 2016 · The Journals of Gerontology Series A
  10. Pathologies Underlying Longitudinal Cognitive Decline in the Oldest Old
    Madeline T. Nguyen, Nora Mattek, Randy L Woltjer, Diane B. Howieson, Lisa C. Silbert, Scott Michael Hofer, Jeffrey Alan Kaye, Hiroko Hayama Dodge, Deniz Erten‐Lyons · 2018 · Alzheimer Disease & Associated Disorders
  11. Could there Be Frailty in the Discrepancy between Lesions and Symptoms of Alzheimer's Disease?
    Marco Canevelli, Giuseppe Bruno, Martina Valletta, Matteo Cesari · 2022 · The Journal of Frailty & Aging
  12. Those Who Hesitate Are Lost: The Case for Setting Behavioral Health Treatment and Disability Standards, Part I
    Pamela A. Warren · 2013 · Psychological Injury and Law
  13. Periodontitis and Tooth Loss Are Associated With Higher Risks of Cognitive Disorders: A Systematic Umbrella Meta‐Analysis
    Balen Hamid Qadir, Mohammed Khalid Mahmood, Yusra Amin, Handren Ameer Kurda, Tara Ali Rasheed, Ahmed Hama Noori, Zana Fuad Noori, Mohammed Aso Abdulghafor, Hevi Nihad Mohammed Fadhil, Mohammed Taib Fatih et al. · 2025 · Clinical and Experimental Dental Research
  14. Dementia With Lewy Bodies: A Common Condition in Nursing Homes?
    John Edward Morley · 2013 · Journal of the American Medical Directors Association
  15. Evaluation of Whole Brain Health in Aging and Alzheimer's Disease: A Standard Procedure for Scoring an MRI-Based Brain Atrophy and Lesion Index
    Hui Guo, Alzheimer’s Disease Neuroimaging Initiative, Xiaowei Song, Matthias Helge Schmidt, Robert A. Vandorpe, Zhan Yang, Emily LeBlanc, Jing Zhang, Steven Beyea, Yunting Zhang et al. · 2014 · Journal of Alzheimer s Disease
  16. Genetic predisposition to higher production of interleukin-6 through -174 G > C polymorphism predicts global cognitive decline in oldest-old with cognitive impairment no dementia
    Vanêssa Gomes Fraga, Henrique Cerqueira Guimarães, Antônio Lúcio Teixeira, Maira Tonidandel Barbosa, Elvis C. C. Mateo, María das Graças Carvalho Ferriani, Paulo Caramelli, Karina Braga Gomes · 2015 · Arquivos de Neuro-Psiquiatria
  17. Prevención de la enfermedad de Alzheimer: un camino a seguir
    Félix Bermejo‐Pareja, Sara Llamas Velasco, Alberto Villarejo‐Galende · 2016 · Revista Clínica Española
  18. SQYZ granules, a traditional Chinese herbal, attenuate cognitive deficits in AD transgenic mice by modulating on multiple pathogenesis processes.
    Haiting An, Dongfeng Wei, Yanjing Qian, Ning Li, Xiaomin Wang · 2018 · Europe PMC (PubMed Central)
  19. A novel neuroimaging signature for ADRD risk stratification in the community
    Claudia Liliana Satizábal, Alexa Beiser, Evan M. Fletcher, Sudha S. Seshadri, Charles S DeCarli · 2023 · Alzheimer s & Dementia
  20. Impairments of inhibitory neurons in amyotrophic lateral sclerosis and frontotemporal dementia
    Félicie Lorenc, Luc Dupuis, Raphaelle Cassel · 2024 · Neurobiology of Disease
  21. Subjective socioeconomic status is associated with risk aversion in a community-based cohort of older adults without dementia
    Gali H. Weissberger, Sungwon Han, Lei Yu, Lisa Laverne Barnes, Melissa Lamar, David Alan Bennett, Patricia A. Boyle · 2022 · Frontiers in Psychology
  22. Fluid biomarker agreement and interrelation in dementia due to Alzheimer’s disease
    Alzheimer’s Disease Neuroimaging Initiative, Panagiotis Alexopoulos, Jennifer Roesler, Lukas Werle, Nathalie Thierjung, Iliana Lentzari, Marion Ortner, Timo Grimmer, Nikolaos Laskaris, Antonios M. Politis et al. · 2017 · Journal of Neural Transmission
  23. Epigenomics of Alzheimer’s Disease
    David Alan Bennett, Lei Yu, Jingyun Yang, Hans‐Ulrich Klein, Philip L. De Jager · 2017 · Elsevier eBooks
  24. What we can learn from animal models about cerebral multi-morbidity
    Siân L. Baker, Jürgen Götz · 2015 · Alzheimer s Research & Therapy
  25. IQ as moderator of terminal decline in perceptual and motor speed, spatial, and verbal ability: Testing the cognitive reserve hypothesis in a population-based sample followed from age 70 until death.
    Valgeir Thorvaldsson, Ingmar Gr. Skoog, Boo E. A. Johansson · 2017 · Psychology and Aging
  26. Pattern Recognition to Objectively Differentiate the Etiology of Cognitive Decline: Analysis of the Impact of Stroke and Alzheimer’s Disease
    Sean Clouston, Lauren L. Richmond, Stacey Scott, Christian C. Luhmann, Ginny Natale, Douglas William Hanes, Yun Zhang, Dylan M. Smith · 2020 · Neuroepidemiology
  27. Combined Cognitive Training and Vortioxetine Mitigates Age-Related Declines in Functional Brain Network Integrity
    Jill D. Waring, Samantha Erin Williams, Angela Stevens, Anja Pogarcic, Joshua S. Shimony, Abraham Z. Snyder, Christopher R. Bowie, Eric J. Lenze · 2023 · American Journal of Geriatric Psychiatry
  28. Assessing the impact of frailty on cognitive function in older adults receiving home care
    Christos F. Kleisiaris, E M Kaffatou, Papathanasiou, Ionna, Emmanouil Androulakis, Panagiotakis, Simeon, Serena Alvino, Chariklia Tziraki · 2019 · PubMed Central
  29. Cognitive decline profiles associated with lewy pathology in the context of Alzheimer’s disease neuropathologic change
    Jon B. Toledo, David P. Salmon, Melissa J. Armstrong, Douglas Galasko · 2024 · Alzheimer s Research & Therapy
  30. Associations between solar and geomagnetic activity and cognitive function in the Normative Aging study
    Jahred M. Liddie, Carolina L. Zilli Vieira, Brent A. Coull, David Sparrow, Petros Koutrakis, Marc G. Weisskopf · 2024 · Environment International
  31. Terminal decline of episodic memory and perceptual speed in a biracial population
    Robert Smith Wilson, Kumar Bharat Rajan, Lisa Laverne Barnes, Willemijn J. Jansen, Priscilla Amofa, Jennifer Weuve, Denis A. Evans · 2017 · Aging Neuropsychology and Cognition
  32. Can we reduce the risk of dementia?: Table 1
    M. Robertson, Anthony Seaton, Lawrence J. Whalley · 2014 · QJM
  33. Alzheimer's disease prevention: A way forward
    Félix Bermejo‐Pareja, Sara Llamas Velasco, Alberto Villarejo‐Galende · 2016 · Revista Clínica Española (English Edition)
  34. Financial and health literacy discrepancies with cognition in older adults.
    Gali H. Weissberger, Sungwon Han, Lei Yu, Lisa Laverne Barnes, David Alan Bennett, Patricia A. Boyle · 2019 · Neuropsychology
  35. Cause of Suspected Non–Alzheimer Disease Pathophysiology
    Sylvia Villeneuve · 2016 · JAMA Neurology
  36. Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology
    Eli Wertman · 2024 · Journal of Clinical Medicine
  37. Treatment preferences among adults with normal cognition and cognitive impairment
    Kelsey M. Owsley, Kenneth M. Langa, Mario Macis, Lauren Hersch Nicholas · 2022 · Journal of the American Geriatrics Society
  38. Integrating the molecular and the population approaches to dementia research to help guide the future development of appropriate therapeutics
    Sally Hunter, Carol Brayne · 2014 · Biochemical Pharmacology
  39. WHO's dementia research priorities: a prescription for failure?
    Lon S. Schneider · 2016 · The Lancet Neurology
  40. Sex-Specific Biological Aging-Related Lipidomic Profiles Mediate the Impact of Urinary Polycyclic Aromatic Hydrocarbon Exposures on Cognitive Function in Healthy Older Adults
    Huimin Ren, Wanying Shi, Xiaojie Guo, Xiao Ma, Jiran Zhang, Yongjun Situ, Chenfeng Li, Chenlong Li, Peijie Sun, Yibo Xu et al. · 2025 · Environment & Health
  41. Rethinking neuropsychological test validity in dementia assessment: a critical review in the age of neuroimaging and digital markers
    Seyul Kwak · 2025 · Frontiers in Human Neuroscience
  42. The Lifetime of Experiences Questionnaire: Psychometric Properties and Relationships With Memory Function in an Iranian Elderly Sample
    Hossein Karsazi, Javad Hatami, Reza Rostami, Ali Moghadamzadeh · 2022 · Frontiers in Psychiatry
  43. Initial development of adult education learning toolkit: Inputs from adult education providers in the Philippines
    Jason Arsua Orozco, Julie S. Berame · 2022 · International Journal of Educational Policy Research and Review
  44. Olfaction and Anxiety Are Differently Associated in Men and Women in Cognitive Physiological and Pathological Aging
    Filippo Cieri, Nicoletta Cera, Aaron R. Ritter, Dietmar Cordes, Jessica Caldwell · 2023 · Journal of Clinical Medicine
  45. Brain aging rejuvenation factors in adults with genetic and sporadic neurodegenerative disease
    Kaitlin Blackstone Casaletto, Rowan Saloner, John Kornak, Adam M. Staffaroni, Saul Villeda, Emily W. Paolillo, Anna M. VandeBunte, Claire J. Cadwallader, Argentina Lario Lago, Julia D Webb et al. · 2024 · Brain Communications
  46. Neuropsychiatric symptom subtypes and dementia‐associated neuropathologic change
    Brenna Cholerton, Gary W. Beecham, Christiane Reitz, Alyssa N. De Vito, Michael L. Cuccaro, Walter A. Kukull, Thomas Jude Montine, Edward D. Huey · 2025 · Alzheimer s & Dementia
  47. Association of Plasma Placental Growth Factor with White Matter Hyperintensities in Alzheimer’s Disease
    Kazuya Igarashi, Tamao Tsukie, Kazuo Washiyama, Kiyoshi Onda, Yuki Miyagi, Shoya Inagawa, Soichiro Shimizu, Akinori Miyashita, Osamu Onodera, Takeshi Ikeuchi et al. · 2025 · Biomolecules
  48. Associations of Alzheimer Disease and Related Dementia Neuropathologies With Timely Diagnosis of Dementia in Healthcare Settings
    Yi Chen, Annie Chen, Melinda C. Power, Francine Grodstein, Alifiya Kapasi, Ana Werneck Capuano, Brittney S. Lange‐Maia, Ali Moghtaderi, Emma K. Stapp, Joya Bhattacharyya et al. · 2026 · Neurology
  49. Temporal Sequence of Incident Mild Cognitive Impairment, Incident Parkinsonism, and Risk of Death in Unimpaired Community-Dwelling Older Adults
    Andrea R. Zammit, Lei Yu, Shahram Oveisgharan, Julie A. Schneider, David Alan Bennett, Aron S. Buchman · 2024 · The Journals of Gerontology Series A
  50. Conditional functional clustering for longitudinal data with heterogeneous nonlinear patterns
    Tianhao Wang, Lei Yu, Sue E. Leurgans, Robert Smith Wilson, David A. A Bennett, Patricia A. Boyle · 2022 · The Annals of Applied Statistics
  51. Measuring disability, physical functions and cognitive abilities of adults: Survey enhancements and options for a new panel study
    Carlos F. Mendes de Leon, Vicki A. Freedman · 2015 · Journal of Economic and Social Measurement
  52. Do Deductive and Probabilistic Reasoning Abilities Decline in Older Adults?
    Jodi M. Tommerdahl, Will McKee, Monica Nesbitt, Mark Donald Ricard, John R. Biggan, Christopher T. Ray, Robert J. Gatchel · 2016 · Journal of Applied Biobehavioral Research
  53. Whole patient knowledge modeling of COVID-19 symptomatology reveals common molecular mechanisms
    Stephan Brock, David Jackson, Theodoros G. Soldatos, Klaus Hornischer, Anne Schäfer, Francesca Diella, Maximilian Y. Emmert, Simon Philipp Hoerstrup · 2023 · Frontiers in Molecular Medicine
  54. Cost-effective case-finding strategies for cognitive impairment with digital twin simulations
    Tau Ming Liew, Way Inn Koay · 2026 · Nature Health
  55. Neurochemical Aspects of Alzheimer Disease
    A. A. Farooqui · 2016 · Springer eBooks
  56. How do we validate approaches that aim to harness reserve to improve the aging brain?
    Lon R. White, Patricia A. Boyle, Thomas C. Foster, Adam H. Gazzaley, John F. Disterhoft · 2019 · Neurobiology of Aging
  57. Cerebral Multimorbidity in Aging
    K. A. Jellinger · 2016 · Journal of Neurology and Neuromedicine
  58. A viewpoint on change point modeling for cognitive aging research: Moving from description to intervention and practice
    Briana N. Sprague, SARA ANN FREED, Christine B. Phillips, Lesley A. Ross · 2019 · Ageing Research Reviews
  59. Structural and Inter-individual Differentiation in Personality Traits Across the Adult Lifespan
    Gabriel Olaru, Kristin Jankowsky, Mathias Allemand · 2023 · European Journal of Personality
  60. Cognitive function and neuropathological outcomes: a forward-looking approach
    Elizabeth Muñoz, Teresa Jenica Filshtein, Brianne Magouirk Bettcher, Donald G. McLaren, Trey Hedden, Douglas Tommet, Dan Mungas, Terry M. Therneau · 2019 · Journal of Neurology
  61. Measuring peripheral markers of neuroinflammation in Alzheimer’s disease – Challenges and opportunities
    Brittany N. Dugger, Ameer Y. Taha · 2020 · Brain Behavior and Immunity
  62. Mediation Analysis in Understanding Mechanism of Alzheimer’s Disease Risk
    Gautam Sajeev · 2015 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  63. Habilidades cognitivas adquiridas ao longo da vida e reserva cognitiva em idosos: desenvolvimento e validação de instrumento
    Isabella Figaro Gattás-Vernaglia · 2019 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  64. Multi-omic subtypes of Alzheimer’s dementia are differentially associated with psychological traits
    Andrea R. Zammit, Lei Yu, Victoria N. Poole, Konstantinos Arfanakis, Julie A. Schneider, Vladislav Petyuk, Philip L. De Jager, Rima F Kaddurah-Daouk, Yasser Iturria‐Medina, David Alan Bennett · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  65. All‐Cause Acute Illness Hospitalisations in the Preceding Two Years Are Associated With Cognitive Decline in Older Adults: The Sydney Memory and Ageing Study
    Lucia Chinnappa‐Quinn, Ben C. P. Lam, Lara Ann Harvey, Nicole A. Kochan, John D. Crawford, Steve Robert Makkar, Henry Brodaty, Perminder Singh Sachdev · 2025 · International Journal of Geriatric Psychiatry
  66. Multidimensional social exclusion and cognitive function in middle-aged and older adults
    Paula Rodrigues, Cláudia Cunha, Gina Voss, Alice Delerue Matos · 2026 · Ageing and Society
  67. Stage-dependent effects of cognitive reserve on memory and brain structural integrity across the spectrum from healthy aging to Alzheimer’s disease
    Laura Serra, Sabrina Bonarota, Giulia Caruso, Matteo Mancini, Sofia Sperati, Carlotta Di Domenico, Federico Maria Tamigi, Francesco Di Lorenzo, Francesco Ricci, Carlo Caltagirone et al. · 2026 · Frontiers in Human Neuroscience
  68. Neuropathology in a diverse cohort of oldest‐old: The LifeAfter90 study
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  69. Cardiorespiratory Fitness, Coronary Artery Calcium, and Risk of Later-Life Dementia
    Yariv Gerber, David Leonard, Kerem Shuval, Carolyn E. Barlow, Clare Meernik, Andjelka Pavlovic, Qing Li, Duke Appiah, Kelley Pettee Gabriel, Nina Butwell Radford et al. · 2026 · JACC Advances
  70. Mediating Role of Inhibition Control in the Relationship Between Age and Memory Changes Throughout Adulthood: An Aging Developmental Study in Iran
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  71. Does losing family members in midlife matter for late-life mental and cognitive health? A longitudinal study of older Swedes spanning 30 years
    Valeria Cecchini, Neda Agahi · 2024 · Aging & Mental Health
  72. Cognitive Aging and the Transition to Early Alzheimer’s Disease
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  73. Associations of stable psychological traits with multi-omic subtypes of Alzheimer’s dementia
    Andrea R. Zammit, Lei Yu, Victoria N. Poole, Shinya Tasaki, Ricardo A. Vialle, Konstantinos Arfanakis, Julie A. Schneider, Vladislav Petyuk, Philip L. De Jager, Rima Kaddurah‐Daouk et al. · 2026 · Translational Psychiatry
  74. Alzheimer's Disease: Current Clinical and Neuropathologic Diagnostic Criteria
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  75. Perceptual and cognitive issues of age-related impairment in complex control environments
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  76. Muscle Strength to Mental Strength: Exercise and Age-Related Cognitive Decline
    Rhianna A. Lovegrove, Mark Bahr · 2020 · Psychology
  77. Physiopathologie de la maladie d'Alzheimer : le rôle central de la plaque amyloïde et de la protéine Tau
    Pierre Krolak‐Salmon · 2020 · NPG. Neurologie, psychiatrie, gériatrie/NPG
  78. Accumulated degeneration of transcriptional regulation contributes to disease development and detrimental clinical outcomes of Alzheimer’s disease
    Guofeng Meng, Dong Lu, Yu Feng, Jijia Sun, Chong Ding, Yan Sun, Xuan Liu, Jiapei Dai, Wenfei Jin, Weidong Zhang · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  79. Asociaciones entre dieta y función cognitiva en el Proyecto SUN
    Mariana Isabel Muñoz · 2022 · Deposito Adademico Digital Universidad De Navarra (University of Navarra)
  80. Multi-‘Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging
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  81. Age, rate of change in neuropathology, and trajectory of cognitive decline
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  82. COMPUTERIZED TOOLS: A SUBSTITUTE OR A SUPPLEMENT WHEN DIAGNOSING ALZHEIMER'S DISEASE?
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  83. Bio-behavioral inquiries regarding cognitive aging and distance to death: The role of gender, APOE, grip strength and subjective memory
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  84. What Most Causes Cognitive Decline Is Not What We've Been Looking For
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  85. The trajectory of functional status before and after vascular events
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  86. The olfactory dysfunctions occurring in the course of Alzheimer’s disease
    Agnieszka Mydlikowska-Śmigórska, Krzysztof Śmigórski · 2017 · Postępy Psychiatrii i Neurologii
  87. Differential Diagnosis Toward a Cure for Alzheimer’s
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  88. Lipid and Genetic Predictors of Midlife Cognitive Decline in Treated HIV-1 Infection
    Shibani S. Mukerji · 2016 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  89. Community and Long‐Term Care Supports for Older Adults with Cognitive Decline
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  90. Estudo comparativo da neuroproteção por anticorpos anti-A? contra a toxicidade de oligômeros de A? em cultura diferenciada de neuroblastoma humano
    Nathalia Reges Pinheiro · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  91. Aging, cognitive ability and the risk of dementia in the Helsinki Birth Cohort Study
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  92. The influence of an 8-week water intervention on executive functioning and mobility in healthy older individuals
    Syndy Grobler · 2018 · SUNScholar (Stellenbosch University)
  93. THE ASSOCIATION OF HABITUAL MILK INTAKE WITH THE RATE OF COGNITIVE DECLINE, AND RISK OF MILD COGNITIVE IMPAIRMENT AND DEMENTIA.
    Natalia Petruski‐Ivleva · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  94. Searching for the Holy Grail Will Need Biomarkers
    Alfredo Ramı́rez · 2020 · The Journal of Prevention of Alzheimer s Disease
  95. Dementia and Neurocognitive Disability
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  96. Neuropathology of Alzheimer’s Disease and Vascular Dementia
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  97. Association between plasma phospho-tau181 and cognitive change from age 73 to 82: Lothian Birth Cohort 1936
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  98. Dementia
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