The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Mechanical hyperalgesias in neuropathic pain patients: Dynamic and static subtypes
Abstract
Two behavioral kinds of mechanical hyperalgesia can be clearly discerned by clinical criteria in patients with neuropathic syndromes, i.e., a dynamic type, elicitable by lightly stroking the symptomatic skin, and a static type, elicitable by steadily applying gentle pressure on it. Of 28 patients studied, 19 had dynamic and 18 had static type mechanical hyperalgesia (9 expressed both types). Experimental compression–ischemia nerve block totally abolished the dynamic hyperalgesia in all patients except in 2, in whom it was markedly diminished. Disappearance of dynamic hyperalgesia occurred contemporaneously with block of myelinated A fibers, as expressed by abolition of the sensations of touch and cold, monitored quantitatively. Static hyperalgesia, however, outlasted A‐fiber block in 15 of 18 patients; the phenomenon persisted during the stage when only unmyelinated fibers were available for impulse conduction. It is thus concluded that, at the primary afferent level, dynamic hyperalgesia is mediated by myelinated fibers, whereas static hyperalgesia depends on unmyelinated afferents. These two kinds of hyperalgesia represent discrete pathophysiological entities with distinct clinical connotations.
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Torebjörk, H. E., Lundberg, L. E., & LaMotte, R. H. (1992) · The Journal of Physiology · doi:10.1113/jphysiol.1992.sp019069 · Cited by 786
Method for quantitative estimation of thermal thresholds in patients.
Fruhstorfer, H., Lindblom, U., & Schmidt, W. C. (1976) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.39.11.1071 · Cited by 781
LaMotte, R. H., Lundberg, L. E., & Torebjörk, H. E. (1992) · The Journal of Physiology · doi:10.1113/jphysiol.1992.sp019068 · Cited by 595
Myelinated afferents signal the hyperalgesia associated with nerve injury
Campbell, J. N., Raja, S. N., Meyer, R. A., & Mackinnon, S. E. (1988) · Pain · doi:10.1016/0304-3959(88)90027-9 · Cited by 562
Dynamic and static components of mechanical hyperalgesia in human hairy skin
Koltzenburg, M., Lundberg, L. E. R., & Torebjörk, E. H. (1992) · Pain · doi:10.1016/0304-3959(92)90262-a · Cited by 523
Baumann, T. K., Simone, D. A., Shain, C. N., & LaMotte, R. H. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.66.1.212 · Cited by 455
ON DISTURBANCES OF SENSATION WITH ESPECIAL REFERENCE TO THE PAIN OF VISCERAL DISEASE
HEAD, H. (1893) · Brain · doi:10.1093/brain/16.1-2.1 · Cited by 398
VERDUGO, R., & OCHOA, J. L. (1992) · Brain · doi:10.1093/brain/115.3.893 · Cited by 349
Self-citationFibre function and perception during cutaneous nerve block.
Mackenzie, R. A., Burke, D., Skuse, N. F., & Lethlean, A. K. (1975) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.38.9.865 · Cited by 275
EXPERIMENTAL EVIDENCE ON THE NATURE OF CUTANEOUS HYPERALGESIA
Hardy, J. D., Wolff, H. G., & Goodell, H. (1950) · Journal of Clinical Investigation · doi:10.1172/jci102227 · Cited by 271
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Quantitative sensory testing: a comprehensive protocol for clinical trials
Rolke, R., Magerl, W., Campbell, K. A., Schalber, C., Caspari, S., Birklein, F., & Treede, R. ‐. (2006) · European Journal of Pain · doi:10.1016/j.ejpain.2005.02.003 · Cited by 1,520
Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms
Jensen, T. S., & Finnerup, N. B. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70102-4 · Cited by 976
Postherpetic Neuralgia: Irritable Nociceptors and Deafferentation
Fields, H. L., Rowbotham, M., & Baron, R. (1998) · Neurobiology of Disease · doi:10.1006/nbdi.1998.0204 · Cited by 561
Development of a Neuropathic Pain Questionnaire
Krause, S. J., & Backonja, M.-M. (2003) · The Clinical Journal of Pain · doi:10.1097/00002508-200309000-00004 · Cited by 454
Secondary hyperalgesia to punctate mechanical stimuli
Ziegler, E. A., Magerl, W., Meyer, R. A., & Treede, R.-D. (1999) · Brain · doi:10.1093/brain/122.12.2245 · Cited by 414
Metadata
- Authors
- Ochoa, J. L., & Yarnitsky, D.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1993-05
- Volume
- 33
- Issue
- 5
- Pages
- 465-472
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2036459878
- Cited by
- 260
- References
- 16
- FWCI
- 3.12
- Type
- journal article
- Language
- en
- Open access
- closed
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