Chemistry and biochemistry of insect hormones
Abstract
Abstract Insect hormones attracted the interest of endocrinologists only comparatively recently. This is partly due to the fact that an equivalent of sex hormones – the classical hormones of vertebrate physiology – is unknown in insects. Castration has no marked effect on the secondary sexual characters. Insect hormones act primarily on developmental processes; the metamorphosis hormone, ecdysone, is the best studied. Recent investigations have shown that ecdysone has the empirical formula C27H44O6 and belongs to the streroids. The mechanism of its action is seen in its influence on the chromosomes. – Other hormone‐like substances, the pheromones, are outstanding for their high activity; a few molecules are sufficient to trigger the characteristic behavioural response.
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The polytene chromosome model allowed description of the induction by 20E of a specific sequence of puffs, a key finding for understanding the mechanism of action of steroid hormones through their binding to nuclear receptors and inducing a sequence of gene activations.
“This biological model allowed description of the induction by 20E of a specific sequence of puffs, and this was a key finding for understanding the mechanism of action of steroid hormones through their binding to nuclear receptors and inducing a sequence of gene activations (Figure 5) [15,16].”
From Ecdysteroids (2021) · cites this paper as [15]
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- Authors
- Karlson, P.
- Affiliations
- Ludwig-Maximilians-Universität München (DE)
- Corresponding author
- Karlson, P.
- Venue
- Angewandte Chemie International Edition in English
- Publisher
- Wiley
- Published
- 1963-04
- Volume
- 2
- Issue
- 4
- Pages
- 175-182
- ISSN
- 0570-0833 (ISSN-L)
- OpenAlex
- W2088655987
- Cited by
- 60
- References
- 55
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 2
- FWCI
- 6.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angewandte Chemie International Edition in English (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect Pheromone Research and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
- Keywords
- insect hormones, ecdysone, steroid hormones, insect development, pheromones, insect endocrinology, hormone action mechanism
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