The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
New Antimalarial Drugs
Abstract
Approximately 40 % of the world population live in areas with the risk of malaria. Each year, 300–500 million people suffer from acute malaria, and 0.5–2.5 million die from the disease. Although malaria has been widely eradicated in many parts of the world, the global number of cases continues to rise. The most important reason for this alarming situation is the rapid spread of malaria parasites that are resistant to antimalarial drugs, especially chloroquine, which is by far the most frequently used. The development of new antimalarial drugs has been neglected since the 1970s owing to the end colonialism, changes in the areas of military engagement, and the restricted market potential. Only in recent years, in part supported by public funding programs, has interest in the development of antimalarial drugs been renewed. New data available from the recently sequenced genome of the malaria parasite Plasmodium falciparum and the application of methods of modern drug design promise to bring significant development in the fight against this disease.
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Citations
Cites
Human Malaria Parasites in Continuous Culture
Trager, W., & Jensen, J. B. (1976) · Science · doi:10.1126/science.781840 · Cited by 7,844
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Rohmer, M., & Rohmer, M. (1999) · Natural Product Reports · doi:10.1039/a709175c · Cited by 1,193
Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs
Jomaa, H., Wiesner, J., Sanderbrand, S., Altincicek, B., Weidemeyer, C., Hintz, M., Türbachova, I., Eberl, M., Zeidler, J., Lichtenthaler, H. K., et al. (1999) · Science · doi:10.1126/science.285.5433.1573 · Cited by 1,173
Self-citationWellems, T. E., & Plowe, C. V. (2001) · The Journal of Infectious Diseases · doi:10.1086/322858 · Cited by 807
Medical need, scientific opportunity and the drive for antimalarial drugs
Ridley, R. G. (2002) · Nature · doi:10.1038/415686a · Cited by 789
A Plastid of Probable Green Algal Origin in Apicomplexan Parasites
Köhler, S., Delwiche, C. F., Denny, P. W., Tilney, L. G., Webster, P., Wilson, R. J. M., Palmer, J. D., & Roos, D. S. (1997) · Science · doi:10.1126/science.275.5305.1485 · Cited by 760
Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum
Waller, R. F., Keeling, P. J., Donald, R. G. K., Striepen, B., Handman, E., Lang-Unnasch, N., Cowman, A. F., Besra, G. S., Roos, D. S., & McFadden, G. I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.21.12352 · Cited by 714
Biochemistry of Plasmodium (malarial parasites)
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Cited by
Nakase, I., Lai, H., Singh, N. P., & Sasaki, T. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.09.003 · Cited by 190
Recent advances in antimalarial drug development
Vangapandu, S., Jain, M., Kaur, K., Patil, P., Patel, S. R., & Jain, R. (2007) · Medicinal Research Reviews · doi:10.1002/med.20062 · Cited by 108
Metadata
- Authors
- Wiesner, J., Ortmann, R., Jomaa, H., & Schlitzer, M.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2003-11-04
- Volume
- 42
- Issue
- 43
- Pages
- 5274-5293
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W1995064146
- Cited by
- 428
- References
- 110
- FWCI
- 22.42
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
