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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Interactions with Aromatic Rings in Chemical and Biological Recognition

Meyer, Emmanuel A., Castellano, Ronald K., Diederich, François·2003·Angewandte Chemie International Edition

Abstract

Intermolecular interactions involving aromatic rings are key processes in both chemical and biological recognition. Their understanding is essential for rational drug design and lead optimization in medicinal chemistry. Different approaches—biological studies, molecular recognition studies with artificial receptors, crystallographic database mining, gas‐phase studies, and theoretical calculations—are pursued to generate a profound understanding of the structural and energetic parameters of individual recognition modes involving aromatic rings. This review attempts to combine and summarize the knowledge gained from these investigations. The review focuses mainly on examples with biological relevance since one of its aims it to enhance the knowledge of molecular recognition forces that is essential for drug development.

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Crossref · 10.1002/anie.200390319

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Metadata

Authors
Meyer, E. A., Castellano, R. K., & Diederich, F.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2003-03-13
Volume
42
Issue
11
Pages
1210-1250
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2048631643
Cited by
3,541
References
3
FWCI
90.44
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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