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Cited by 350

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

A Near‐Infrared‐Fluorescence‐Quenched Gold‐Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination

Lee, Seulki, Cha, Eui‐Joon, Park, Kyeongsoon, Lee, Seung‐Young, Hong, Jin‐Ki, Sun, In‐Cheol, Kim, Sang Yoon, Choi, Kuiwon, Kwon, Ick Chan, Kim, Kwangmeyung, Ahn, Cheol‐Hee·2008·Angewandte Chemie International Edition

Abstract

Nanodiagnosis: A matrix-metalloproteinase (MMP) sensitive gold-nanoparticle (AuNP) imaging probe quenches conjugated near-infrared (NIR) dyes with high efficiency and is specifically activated by the target MMPs (see picture, left). With this system, nanomolar amounts of protease can be detected—both in vitro and in vivo. Experiments disclose an apparent positive contrast in MMPs-positive tumor-bearing mice (right).

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Crossref · 10.1002/anie.200705240

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Metadata

Authors
Lee, S., Cha, E., Park, K., Lee, S., Hong, J., Sun, I., Kim, S. Y., Choi, K., Kwon, I. C., Kim, K., & Ahn, C.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2008-03-20
Volume
47
Issue
15
Pages
2804-2807
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2008300958
Cited by
350
References
2
FWCI
22.81
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Near‐Infrared‐Fluorescence‐Quenched Gold‐Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination. https://app.cochat.ai/papers/10.1002/anie.200705240
The paper
Lee, S., Cha, E., Park, K., Lee, S., Hong, J., Sun, I., Kim, S. Y., Choi, K., Kwon, I. C., Kim, K., & Ahn, C. (2008). A Near‐Infrared‐Fluorescence‐Quenched Gold‐Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200705240

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