The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Hydrolytic Stability of Hydrazones and Oximes
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Watching C 'n' N: Hydrazones and oximes are common conjugates but are labile to hydrolysis. The hydrolytic stabilities of isostructural hydrazones and one oxime were determined at pD 5.0–9.0. The rate constant for the acid-catalyzed hydrolysis of the oxime was nearly 103-fold lower than those for simple hydrazones, and a trialkylhydrazonium ion (formed after condensation) was even more stable than the oxime.
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Cites
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
Mahal, L. K., Yarema, K. J., & Bertozzi, C. R. (1997) · Science · doi:10.1126/science.276.5315.1125 · Cited by 796
Carey, F. A., & Sundberg, R. J. (1995) · Springer eBooks · doi:10.1007/978-1-4613-9792-2 · Cited by 778
Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase
Chen, I., Howarth, M., Lin, W., & Ting, A. Y. (2005) · Nature Methods · doi:10.1038/nmeth735 · Cited by 667
A General Mechanism for Vitamin B6-catalyzed Reactions1
Metzler, D. E., Ikawa, M., & Snell, E. E. (1954) · Journal of the American Chemical Society · doi:10.1021/ja01632a004 · Cited by 633
Nucleophilic Catalysis of Oxime Ligation
Dirksen, A., Hackeng, T. M., & Dawson, P. E. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200602877 · Cited by 488
Dirksen, A., Dirksen, S., Hackeng, T. M., & Dawson, P. E. (2006) · Journal of the American Chemical Society · doi:10.1021/ja067189k · Cited by 433
Studies on the Mechanism of Oxime and Semicarbazone Formation1
Jencks, W. P. (1959) · Journal of the American Chemical Society · doi:10.1021/ja01511a053 · Cited by 346
The Mechanism of Hydrolysis of Schiff Bases Derived from Aliphatic Amines
Cordes, E. H., & Jencks, W. P. (1963) · Journal of the American Chemical Society · doi:10.1021/ja00901a037 · Cited by 318
Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein
Kochendoerfer, G. G., Chen, S.-Y., Mao, F., Cressman, S., Traviglia, S., Shao, H., Hunter, C. L., Low, D. W., Cagle, E. N., Carnevali, M., et al. (2003) · Science · doi:10.1126/science.1079085 · Cited by 312
Studies on the Mechanism of Oxime and Semicarbazone Formation
JENCKS, W. P. (1968) · Organic Functional Group Analysis · doi:10.1016/b978-0-08-203484-1.50017-x · Cited by 306
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Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis
Kölmel, D. K., & Kool, E. T. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00090 · Cited by 699
Lou, J., Stowers, R., Nam, S., Xia, Y., & Chaudhuri, O. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.004 · Cited by 523
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Wong, P. T., & Choi, S. K. (2015) · Chemical Reviews · doi:10.1021/cr5004634 · Cited by 507
Oxime-Based and Catalyst-Free Dynamic Covalent Polyurethanes
Liu, W.-X., Zhang, C., Zhang, H., Zhao, N., Yu, Z.-X., & Xu, J. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b03967 · Cited by 426
Design Challenges in Polymeric Scaffolds for Tissue Engineering
Echeverria Molina, M. I., Malollari, K. G., & Komvopoulos, K. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.617141 · Cited by 397
Metadata
- Authors
- Kalia, J., & Raines, R. T.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2008-09-09
- Volume
- 47
- Issue
- 39
- Pages
- 7523-7526
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2010621614
- Cited by
- 916
- References
- 19
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- green
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