The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Nanogels as Pharmaceutical Carriers: Finite Networks of Infinite Capabilities
Open accessAbstract
Nanogels are swollen nanosized networks composed of hydrophilic or amphiphilic polymer chains. They are developed as carriers for the transport of drugs, and can be designed to spontaneously incorporate biologically active molecules through formation of salt bonds, hydrogen bonds, or hydrophobic interactions. Polyelectrolyte nanogels can readily incorporate oppositely charged low‐molecular‐mass drugs and biomacromolecules such as oligo‐ and polynucleotides (siRNA, DNA) as well as proteins. The guest molecules interact electrostatically with the ionic polymer chains of the gel and become bound within the finite nanogel. Multiple chemical functionalities can be employed in the nanogels to introduce imaging labels and to allow targeted drug delivery. The latter can be achieved, for example, with degradable or cleavable cross‐links. Recent studies suggest that nanogels have a very promising future in biomedical applications.
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Cites
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New-Concept Chemotherapy by Nanoparticles of Biodegradable Polymers: Where Are We Now?
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Soft Nanotechnology with Soft Nanoparticles
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Direct Fabrication and Harvesting of Monodisperse, Shape-Specific Nanobiomaterials
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Cited by
Sahay, G., Alakhova, D. Y., & Kabanov, A. V. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.01.036 · Cited by 2,181
Self-citationControlled drug delivery vehicles for cancer treatment and their performance
Senapati, S., Mahanta, A. K., Kumar, S., & Maiti, P. (2018) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-017-0004-3 · Cited by 2,167
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine
Egorova, K. S., Gordeev, E. G., & Ananikov, V. P. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00562 · Cited by 1,649
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Metadata
- Authors
- Kabanov, A. V., & Vinogradov, S. V.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2009-07-08
- Volume
- 48
- Issue
- 30
- Pages
- 5418-5429
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2150918607
- Cited by
- 1,313
- References
- 84
- FWCI
- 26.29
- Type
- journal article
- Language
- en
- Open access
- green
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