New-Concept Chemotherapy by Nanoparticles of Biodegradable Polymers: Where Are We Now?

In vivo cancer targeting and imaging with semiconductor quantum dots

Gao, X., Cui, Y., Levenson, R. M., Chung, L. W. K., & Nie, S. (2004) · Nature Biotechnology · doi:10.1038/nbt994 · Cited by 4,775 · see citing works

Cancer nanotechnology: opportunities and challenges

Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558 · see citing works

Drug Delivery Systems: Entering the Mainstream

Allen, T. M., & Cullis, P. R. (2004) · Science · doi:10.1126/science.1095833 · Cited by 4,552 · see citing works

Biodegradable polymeric nanoparticles as drug delivery devices

Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00339-4 · Cited by 3,549 · see citing works

Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins

Nam, J., Thaxton, C. S., & Mirkin, C. A. (2003) · Science · doi:10.1126/science.1088755 · Cited by 2,391 · see citing works

Conformations of Polymers Attached to an Interface

de Gennes, P. G. (1980) · Macromolecules · doi:10.1021/ma60077a009 · Cited by 2,359 · see citing works

Nanoparticle-Based Bio-Barcodes for the Ultrasensitive Detection of Proteins*

Nam, J., Thaxton, C. S., & Mirkin, C. A. (2020) · Spherical Nucleic Acids · doi:10.1201/9781003056713-94 · Cited by 2,038 · see citing works

Nanomedicine: current status and future prospects

Moghimi, S. M., Hunter, A. C., & Murray, J. C. (2005) · The FASEB Journal · doi:10.1096/fj.04-2747rev · Cited by 2,029 · see citing works

Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs

Yin Win, K., & Feng, S.-S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.050 · Cited by 1,452 · see citing works

Poly(ethylene glycol) chemistry : biotechnical and biomedical applications

Harris, J. M. (1992) · Plenum Press eBooks · Cited by 1,426 · see citing works

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

Allen, T. M., Hansen, C., Martin, F., Redemann, C. T., & Yau‐Young, A. O. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90246-5 · Cited by 1,392 · see citing works

Optimizing Liposomes for Delivery of Chemotherapeutic Agents to Solid Tumors

Drummond, D. C., Meyer, O., Hong, K., Kirpotin, D. B., & Papahadjopoulos, D. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01426-1 · Cited by 1,265 · see citing works

Monoclonal antibody therapy of cancer

Adams, G. P., & Weiner, L. M. (2005) · Nature Biotechnology · doi:10.1038/nbt1137 · Cited by 1,254 · see citing works

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

Moghimi, S. M., & Szebeni, J. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00033-x · Cited by 1,228 · see citing works

In vivo molecular and cellular imaging with quantum dots

Gao, X., Yang, L. P. H., Petros, J. A., Marshall, F. F., Simons, J. W., & Nie, S. (2004) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2004.11.003 · Cited by 1,213 · see citing works

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

Gabizón, A., & Papahadjopoulos, D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.18.6949 · Cited by 1,134 · see citing works

Handbook of Water Soluble Gums and Resins

Davidson, R. L. (1980) · Cited by 1,037 · see citing works

Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

Caliceti, P. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(03)00108-x · Cited by 948 · see citing works

Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS

Maeda, H., Sawa, T., & Konno, T. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00309-1 · Cited by 926 · see citing works

Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer

Nahta, R., Yu, D., Hung, M., Hortobágyi, G. N., & Esteva, F. J. (2006) · Nature Clinical Practice Oncology · doi:10.1038/ncponc0509 · Cited by 916 · see citing works

Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer

Kukowska‐Latallo, J. F., Candido, K. A., Cao, Z., Nigavekar, S. S., Majoros, I., Thomas, T. P., Balogh, L. P., Khan, M. K., & Baker, J. R. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3921 · Cited by 912 · see citing works

Uptake and Cytotoxicity of Chitosan Molecules and Nanoparticles: Effects of Molecular Weight and Degree of Deacetylation

Huang, M., Khor, E., & Lim, L. Y. (2004) · Pharmaceutical Research · doi:10.1023/b:pham.0000016249.52831.a5 · Cited by 853 · see citing works

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity

Fonseca, C., Simões, S., & Gaspar, R. S. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00212-2 · Cited by 757 · see citing works

Distribution and Tissue Uptake of Poly(ethylene glycol) with Different Molecular Weights after Intravenous Administration to Mice

Yamaoka, T., Tabata, Y., & Ikada, Y. (1994) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600830432 · Cited by 751 · see citing works

Biomaterials in Drug Delivery and Tissue Engineering: One Laboratory's Experience

Langer, R. (1999) · Accounts of Chemical Research · doi:10.1021/ar9800993 · Cited by 751 · see citing works

A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing vitamin E TPGS

Li, M., & Feng, S. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00320-6 · Cited by 727 · see citing works

Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating

Wilhelm, C., Billotey, C., Roger, J., Pons, J.-N., Bacri, J.-C., & Gazeau, F. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00440-4 · Cited by 675 · see citing works

Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.

Park, J. W., Hong, K., Kirpotin, D. B., Colbern, G. T., Shalaby, R., Baselga, J. M., Shao, Y. Y., Nielsen, U. B., Marks, J. D., Moore, D. H., et al. (2002) · PubMed · Cited by 647 · see citing works

Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

GUPTA, B., Levchenko, T. S., & Torchilin, V. P. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.10.007 · Cited by 632 · see citing works

Fate and behavior of liposomes in vivo: a review of controlling factors.

Senior, J. H. (1987) · PubMed · Cited by 592 · see citing works

Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?

Jung, T. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00084-9 · Cited by 586 · see citing works

Nano and microparticles as controlled drug delivery devices.

Kumar, M. N. R. (2000) · PubMed · Cited by 532 · see citing works

Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs

Dong, Y., & Feng, S. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.055 · Cited by 468 · see citing works

Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues

Allen, T. M., Hansen, C., & Rutledge, J. M. (1989) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(89)90078-3 · Cited by 467 · see citing works

Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity

Torchilin, V. P., Omelyanenko, V. G., Papisov, M. I., Bogdanov, A. A., Jr., Trubetskoy, V. S., Herron, J. N., & Gentry, C. A. (1994) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)90003-5 · Cited by 466 · see citing works

Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes

Liu, D., Mori, A., & Huang, L. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90136-a · Cited by 464 · see citing works

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.

Chonn, A., Semple, S. C., & Cullis, P. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)37026-7 · Cited by 461 · see citing works

Ligand-targeted liposomal anticancer drugs

Sapra, P., & Allen, T. M. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00032-8 · Cited by 438 · see citing works

Cytotoxic studies of paclitaxel (Taxol®) in human tumour cell lines

Liebmann, J., Cook, J. A., Lipschultz, C. A., Teague, D., Fisher, J. K., & Mitchell, J. (1993) · British Journal of Cancer · doi:10.1038/bjc.1993.488 · Cited by 429 · see citing works

The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)–tocopheryl polyethylene glycol succinate nanoparticles

Zhang, Z., & Feng, S. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.03.006 · Cited by 415 · see citing works

Effects of emulsifiers on the controlled release of paclitaxel (Taxol®) from nanospheres of biodegradable polymers

Feng, S., & Huang, G. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00364-3 · Cited by 400 · see citing works

Poly(d,l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs

Dong, Y., & Feng, S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.03.021 · Cited by 396 · see citing works

Controlling the Physical Behavior and Biological Performance of Liposome Formulations Through Use of Surface Grafted Poly(ethylene Glycol)

Allen, C. J., Santos, N. D., Gallagher, R., Chiu, G. N. C., Shu, Y., Li, W. M., Johnstone, S. A., Janoff, A. S., Mayer, L. D., Webb, M. S., et al. (2002) · Bioscience Reports · doi:10.1023/a:1020186505848 · Cited by 388 · see citing works

Lymphatic uptake and biodistribution of liposomes after subcutaneous injection.

Oussoren, C., Zuidema, J., Crommelin, D. J. A., & Storm, G. (1997) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(97)00122-3 · Cited by 381 · see citing works

In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin–PLGA conjugates

Yoo, H. S., Lee, K. H., Oh, J. E., & Park, T. G. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00280-7 · Cited by 375 · see citing works

Comparative Uptake Studies of Bioadhesive and Non-Bioadhesive Nanoparticles in Human Intestinal Cell Lines and Rats: The Effect of Mucus on Particle Adsorption and Transport

Behrens, I., Pena, A. I. V., Alonso, M. J., & Kissel, T. (2002) · Pharmaceutical Research · doi:10.1023/a:1019854327540 · Cited by 372 · see citing works

The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes

Chonn, A., Cullis, P. R., & Devine, D. V. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.146.12.4234 · Cited by 367 · see citing works

Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes

Ishida, T., Harada, M., Wang, X., Ichihara, M., Irimura, K., & Kiwada, H. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.04.003 · Cited by 365 · see citing works

Repulsive interactions and mechanical stability of polymer-grafted lipid membranes

Needham, D., McIntosh, T. J., & Lasič, D. D. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90112-y · Cited by 364 · see citing works

Chemotherapeutic engineering: Application and further development of chemical engineering principles for chemotherapy of cancer and other diseases

Feng, S., & Chien, S. (2003) · Chemical Engineering Science · doi:10.1016/s0009-2509(03)00234-3 · Cited by 364 · see citing works

New Amphipatic Polymer-Lipid Conjugates Forming Long-Circulating Reticuloendothelial System-Evading Liposomes

Woodle, M. C., Engbers, C. M., & Zalipsky, S. (1994) · Bioconjugate Chemistry · doi:10.1021/bc00030a001 · Cited by 361 · see citing works

Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes

Crosasso, P., Ceruti, M., Brusa, P., Arpicco, S., Dosio, F., & Cattel, L. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00166-2 · Cited by 338 · see citing works

Development and characterization of a novel Cremophor® EL free liposome-based paclitaxel (LEP-ETU) formulation

Zhang, J. A., Anyarambhatla, G., Ma, L., Ugwu, S. O., Xuan, T., Sardone, T., & Ahmad, I. N. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.06.009 · Cited by 335 · see citing works

Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol®)

Li, M., & Feng, S. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00025-1 · Cited by 329 · see citing works

Liposome Clearance

Ishida, T., Harashima, H., & Kiwada, H. (2002) · Bioscience Reports · doi:10.1023/a:1020134521778 · Cited by 329 · see citing works

Biodegradable Polymers for Microencapsulation of Drugs

Park, J. H., Ye, M., & Park, K. (2005) · Molecules · doi:10.3390/10010146 · Cited by 318 · see citing works

Molecular mechanism of the lipid vesicle longevity in vivo

Blume, G., & Cevc, G. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90351-y · Cited by 314 · see citing works

Nanoparticles of Biodegradable Polymers for Clinical Administration of Paclitaxel

Feng, S., Li, M., Win, K. Y., & Huang, G. (2004) · Current Medicinal Chemistry · doi:10.2174/0929867043455909 · Cited by 311 · see citing works

Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells

Mamot, C., Drummond, D. C., Greiser, U., Hong, K., Kirpotin, D. B., Marks, J. D., & Park, J. W. (2004) · The Women s Oncology Review · doi:10.3109/14733400410001727592 · Cited by 298 · see citing works

Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function

Jain, R. K. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00306-6 · Cited by 298 · see citing works

Factors Affecting the Accelerated Blood Clearance of Polyethylene Glycol-Liposomes upon Repeated Injection

Laverman, P., Carstens, M. G., Boerman, O. C., Dams, E. T. M., Oyen, W. J. G., van Rooijen, N., Corstens, F. H. M., & Storm, G. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29419-2 · Cited by 298 · see citing works

Serum opsonins and liposomes: their interaction and opsonophagocytosis.

Hm, P. (1992) · PubMed · Cited by 298 · see citing works

Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs

Felnerova, D., Viret, J., Glück, R., & Moser, C. (2004) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2004.10.005 · Cited by 297 · see citing works

Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody

Lukyanov, A. N., ElBayoumi, T. A., Chakilam, A. R., & Torchilin, V. P. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.08.007 · Cited by 294 · see citing works

Fabrication, characterization and in vitro release of paclitaxel (Taxol®) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers

Li, M., & Feng, S. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00440-0 · Cited by 286 · see citing works

Enhanced Hepatic Uptake of Liposomes Through Complement Activation Depending on the Size of Liposomes

Harashima, H., Sakata, K., Funato, K., & Kiwada, H. (1994) · Pharmaceutical Research · doi:10.1023/a:1018965121222 · Cited by 285 · see citing works

Therapy of leishmaniasis: Superior efficacies of liposome-encapsulated drugs

Alving, C. R., Steck, E. A., Chapman, W. L., Waits, V. B., Hendricks, L. D., Swartz, G. M., & Hanson, W. L. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.6.2959 · Cited by 284 · see citing works

Anisamide‐targeted stealth liposomes: A potent carrier for targeting doxorubicin to human prostate cancer cells

Banerjee‬‬‬‬‬‬‬‬‬, R., Tyagi, P., Li, S., & Huang, L. (2004) · International Journal of Cancer · doi:10.1002/ijc.20452 · Cited by 274 · see citing works

Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serum

Moghimi, S. M., Muir, I. S., Illum, L., Davis, S. S., & Kolb‐Bachofen, V. (1993) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(93)90137-e · Cited by 259 · see citing works

Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo

Ishida, O., Maruyama, K., Tanahashi, H., Iwatsuru, M., Sasaki, K., Eriguchi, M., & Yanagië, H. (2001) · Pharmaceutical Research · doi:10.1023/a:1010960900254 · Cited by 258 · see citing works

Phase I and pharmacokinetic study of MCC-465, a doxorubicin (DXR) encapsulated in PEG immunoliposome, in patients with metastatic stomach cancer

Matsumura, Y., Gotoh, M., Muro, K., Yamada, Y., Shirao, K., Shimada, Y., Okuwa, M., Matsumoto, S., Miyata, Y., Ohkura, H., et al. (2004) · Annals of Oncology · doi:10.1093/annonc/mdh092 · Cited by 253 · see citing works

PLGA/TPGS Nanoparticles for Controlled Release of Paclitaxel: Effects of the Emulsifier and Drug Loading Ratio

Li, M., & Feng, S. (2003) · Pharmaceutical Research · doi:10.1023/b:pham.0000003387.15428.42 · Cited by 250 · see citing works

Liposome—complement interactions in rat serum: implications for liposome survival studies

Devine, D. V., Wong, K., Serrano, K., Chonn, A., & Cullis, P. R. (1994) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)90231-3 · Cited by 248 · see citing works

Advantages of liposomal delivery systems for anthracyclines

Allen, T. M., & Martin, F. J. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.08.001 · Cited by 248 · see citing works

Lipophilic drug derivatives in liposomes

Gulati, M., Grover, M., Singh, S., et al. (1998) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00006-4 · Cited by 244 · see citing works

In Vitro and in Vivo Study of Two Types of Long-Circulating Solid Lipid Nanoparticles Containing Paclitaxel.

Chen, D., Yang, T.-Z., Lü, W.-L., & Zhang, Q. (2001) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.49.1444 · Cited by 243 · see citing works

Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: Synthesis, formulation, characterization and in vitro drug release

Zhang, Z., & Feng, S.-S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.05.104 · Cited by 240 · see citing works

Amphiphilic vinyl polymers effectively prolong liposome circulation time in vivo

Torchilin, V. P., Shtilman, M. I., Trubetskoy, V. S., Whiteman, K. R., & Milstein, A. M. (1994) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)90025-6 · Cited by 239 · see citing works

Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel

Immordino, M. L., Brusa, P., Arpicco, S., Stella, B., Dosio, F., & Cattel, L. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00271-2 · Cited by 238 · see citing works

Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages.

Nishikawa, K., Arai, H., & Inoue, K. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)34110-9 · Cited by 233 · see citing works

Targeted imaging using ultrasound

Dayton, P. A., & Ferrara, K. W. (2002) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10173 · Cited by 233 · see citing works

Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes

Song, L. Y., AHKONG, Q. F., Rong, Q., Wang, Z., Ansell, S. M., Hope, M. J., & Mui, B. L. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00399-6 · Cited by 229 · see citing works

Subcutaneous administration of liposomes: a comparison with the intravenous and intraperitoneal routes of injection

Allen, T. M., Hansen, C. B., & Guo, L. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90115-g · Cited by 228 · see citing works

Targeted contrast agents for magnetic resonance imaging and ultrasound

Morawski, A. M., Lanza, G., & Wickline, S. A. (2004) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2004.11.001 · Cited by 223 · see citing works

A lipid based depot (DepoFoam® technology) for sustained release drug delivery

Mantripragada, S. B. (2002) · Progress in Lipid Research · doi:10.1016/s0163-7827(02)00004-8 · Cited by 222 · see citing works

Development and characterization of a novel liposome-based formulation of SN-38

Zhang, J. A., Xuan, T., Parmar, M. M., et al. (2003) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2003.10.015 · Cited by 220 · see citing works

Cationic Liposomes Coated with Polyethylene Glycol As Carriers for Oligonucleotides

Meyer, O., Kirpotin, D. B., Hong, K., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15621 · Cited by 217 · see citing works

Amphiphilic poly-N-vinylpyrrolidones:

Torchilin, V. P., Levchenko, T. S., Whiteman, K. R., Yaroslavov, A. A., Tsatsakis, A. M., Rizos, A. K., Michailova, E. V., & Shtilman, M. I. (2001) · Biomaterials · doi:10.1016/s0142-9612(01)00050-3 · Cited by 214 · see citing works

Stabilization of Substances in Circulation

Monfardini, C., & Veronese, F. M. (1998) · Bioconjugate Chemistry · doi:10.1021/bc970184f · Cited by 212 · see citing works

Nanoparticles of biodegradable polymers for new-concept chemotherapy

Feng, S. (2004) · Expert Review of Medical Devices · doi:10.1586/17434440.1.1.115 · Cited by 207 · see citing works

Intracellular targeting of sodium mercaptoundecahydrododecaborate (BSH) to solid tumors by transferrin-PEG liposomes, for boron neutron-capture therapy (BNCT)

Maruyama, K., Ishida, O., Kasaoka, S., et al. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.04.018 · Cited by 207 · see citing works

Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats

Takeuchi, H., Kojima, H., Yamamoto, H., & Kawashimà, Y. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00368-6 · Cited by 205 · see citing works

Tumor-Targeted Gene Delivery Using Poly(Ethylene Glycol)-Modified Gelatin Nanoparticles: In Vitro and in Vivo Studies

Kaul, G., & Amiji, M. M. (2005) · Pharmaceutical Research · doi:10.1007/s11095-005-4590-3 · Cited by 204 · see citing works

Targeted Liposomal Drug Delivery in Cancer

Medina, O. P., Zhu, Y., & Kairemo, K. (2004) · Current Pharmaceutical Design · doi:10.2174/1381612043383467 · Cited by 200 · see citing works

New Detachable Poly(ethylene glycol) Conjugates: Cysteine-Cleavable Lipopolymers Regenerating Natural Phospholipid, Diacyl Phosphatidylethanolamine

Zalipsky, S., Qazen, M. M., Walker, J. A., Mullah, N. N., Quinn, Y. P., & Huang, S. K. (1999) · Bioconjugate Chemistry · doi:10.1021/bc990031n · Cited by 198 · see citing works

Pegylated liposomal doxorubicin‐efficacy in patients with recurrent high‐grade glioma

Hau, P., Fabel, K. S., Baumgart, U., Rümmele, P., Grauer, O. M., Bock, A., Dietmaier, C., Dietmaier, W., Dietrich, J., Dudel, C., et al. (2004) · Cancer · doi:10.1002/cncr.20073 · Cited by 197 · see citing works

Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer

Kopelman, R., Koo, Y.-E. L., Philbert, M. A., Moffat, B. A., Reddy, G. R., McConville, P., Hall, D. E., Chenevert, T. L., Bhojani, M. S., Buck, S. M., et al. (2005) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2005.02.061 · Cited by 193 · see citing works

Multifunctional Nano-Architecture for Biomedical Applications

Ma, D., Guan, J., Normandin, F., Dénommée, S., Enright, G. D., Veres, T., & Simard, B. (2006) · Chemistry of Materials · doi:10.1021/cm052067x · Cited by 191 · see citing works

Phase I–II study of pegylated liposomal cisplatin (SPI-077™) in patients with inoperable head and neck cancer

Harrington, K. J., Lewanski, C. R., Northcote, A. D., et al. (2001) · Annals of Oncology · doi:10.1023/a:1011199028318 · Cited by 182 · see citing works

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis

Nielsen, U. B., Kirpotin, D. B., Pickering, E. M., et al. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(02)00256-2 · Cited by 178 · see citing works

Immunotherapy of folate receptor-expressing tumors: review of recent advances and future prospects

Lü, Y. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00215-3 · Cited by 172 · see citing works

New Synthetic Amphiphilic Polymers for Steric Protection of Liposomes in Vivo

Torchilin, V. P., Trubetskoy, V. S., Whiteman, K. R., Ferruti, P., Veronese, F. M., & Caliceti, P. (1995) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600840904 · Cited by 168 · see citing works

β2-Glycoprotein I Is a Major Protein Associated with Very Rapidly Cleared Liposomes in Vivo, Suggesting a Significant Role in the Immune Clearance of “Non-self” Particles

Chonn, A., Semple, S. C., & Cullis, P. R. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.43.25845 · Cited by 167 · see citing works

Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma

Zamboni, W. C., Gervais, A. C., Egorin, M. J., Schellens, J. H. M., Zuhowski, E. G., Pluim, D., Joseph, E., Hamburger, D. R., Working, P. K., Colbern, G. T., et al. (2004) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-003-0719-4 · Cited by 166 · see citing works

Determinants of drug delivery and transport to solid tumors

Au, J. L., Jang, S., Zheng, J., Chen, C.-T., Song, S., Hu, L., & Wientjes, M. G. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00308-x · Cited by 165 · see citing works

Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models.

Tardi, P. G., CHOICE, E., Masin, D., Redelmeier, T. E., Bally, M. B., & Madden, T. D. (2000) · PubMed · Cited by 160 · see citing works

Paclitaxel-loaded PLGA nanoparticles: Potentiation of anticancer activity by surface conjugation with wheat germ agglutinin

Mo, Y., & Lim, L. Y. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.08.013 · Cited by 155 · see citing works

Pegylated Liposomal Doxorubicin: Optimizing the Dosing Schedule in Ovarian Cancer

Rose, P. G. (2005) · The Oncologist · doi:10.1634/theoncologist.10-3-205 · Cited by 155 · see citing works

Transfer and exchange of phospholipid between small unilamellar liposomes and rat plasma high density lipoproteins Dependence on cholesterol content and phospholipid composition

Damen, J., Regts, J., & Scherphof, G. L. (1981) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(81)90268-x · Cited by 154 · see citing works

Nanotechnology Takes Aim at Cancer

Service, R. F. (2005) · Science · doi:10.1126/science.310.5751.1132 · Cited by 154 · see citing works

Use of liposomal anthracyclines in Kaposi’s sarcoma

Krown, S. E., Northfelt, D., Osoba, D., & Stewart, J. S. W. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.08.003 · Cited by 150 · see citing works

Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins

Mahmood, I., & Green, M. D. (2005) · Clinical Pharmacokinetics · doi:10.2165/00003088-200544040-00001 · Cited by 150 · see citing works

Polyethylene Glycol-Modified Liposome-Encapsulated Hemoglobin: A Long Circulating Red Cell Substitute

Phillips, W. T., Klipper, R. W., Awasthi, V., Rudolph, A. S., Cliff, R. O., Kwasiborski, V., & Goins, B. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38004-8 · Cited by 149 · see citing works

In vitro and in vivo studies on vitamin E TPGS-emulsified poly(d,l-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation

Win, K. Y., & Feng, S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.11.008 · Cited by 149 · see citing works

A Novel Family of l -Amino Acid-Based Biodegradable Polymer−Lipid Conjugates for the Development of Long-Circulating Liposomes with Effective Drug-Targeting Capacity

Metselaar, J. M., de Bruin, P., de Boer, L. W. T., de Vringer, T., Snel, C. J., Oussoren, C., Wauben, M. H. M., Crommelin, D. J. A., Storm, G., & Hennink, W. E. (2003) · Bioconjugate Chemistry · doi:10.1021/bc0340363 · Cited by 149 · see citing works

Toward Selection of Internalizing Antibodies from Phage Libraries

Becerril, B., Poul, M., & Marks, J. D. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0177 · Cited by 148 · see citing works

Is half‐life of circulating liposomes determined by changes in their permeability?

Senior, J., & Gregoriadis, G. C. (1982) · FEBS Letters · doi:10.1016/0014-5793(82)81216-7 · Cited by 148 · see citing works

Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice.

Pastorino, F., Brignole, C., Marimpietri, D., et al. (2003) · PubMed · Cited by 147 · see citing works

Protein adsorption to polyethylene glycol modified liposomes from fibrinogen solution and from plasma

Price, M., Cornelius, R. M., & Brash, J. L. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00330-3 · Cited by 147 · see citing works

Relaxivity of liposomal paramagnetic MRI contrast agents

Strijkers, G. J., Mulder, W. J. M., van Heeswijk, R. B., Frederik, P. M., Bomans, P. H. H., Magusin, P. C. M. M., & Nicolay, K. (2005) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-005-0111-y · Cited by 146 · see citing works

In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery

Xu, Z., Gu, W., Huang, J. C., et al. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2004.10.009 · Cited by 145 · see citing works

Efficacy and safety of liposomal anthracyclines in Phase I/II clinical trials

Alberts, D. S., Muggia, F. M., Carmichael, J., Winer, E. P., Jahanzeb, M., Venook, A. P., Skubitz, K. M., Rivera, E., Sparano, J. A., DiBella, N. J., et al. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.08.010 · Cited by 139 · see citing works

Long Circulating Liposomes: Old Drugs, New Therapeutics

Woodle, M. C., & Storm, G. (1998) · Springer eBooks · doi:10.1007/978-3-662-22115-0 · Cited by 136 · see citing works

Nanotechnology for drug and gene therapy: the importance of understanding molecular mechanisms of delivery

Labhasetwar, V. D. (2005) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2005.10.009 · Cited by 136 · see citing works

Magnetic resonance molecular imaging with nanoparticles

Lanza, G. M., Winter, P. M., Caruthers, S. D., Morawski, A. M., Schmieder, A. H., Crowder, K. C., & Wickline, S. A. (2004) · Journal of Nuclear Cardiology · doi:10.1016/j.nuclcard.2004.09.002 · Cited by 135 · see citing works

A phase II study of STEALTH cisplatin (SPI-77) in patients with advanced non-small cell lung cancer

Kim, E. S., Lu, C., Khuri, F. R., et al. (2001) · Lung Cancer · doi:10.1016/s0169-5002(01)00278-1 · Cited by 135 · see citing works

Tuftsin-bearing liposomes in treatment of macrophage-based infections

Agrawal, A. K., & Gupta, C. M. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(99)00061-7 · Cited by 134 · see citing works

Interaction of C-reactive protein with artificial phosphatidylcholine bilayers and complement.

Volanakis, J. E., & Narkates, A. J. (1981) · The Journal of Immunology · doi:10.4049/jimmunol.126.5.1820 · Cited by 132 · see citing works

Inhibition of Liposome-Induced Complement Activation by Incorporated Poly(Ethylene Glycol)-Lipids

Bradley, A. J., Devine, D. V., Ansell, S. M., Janzen, J., & Brooks, D. E. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1998.0798 · Cited by 132 · see citing works

Stability of Liposomal Formulations in Physiological Conditions for Oral Drug Delivery

Taira, M. C., Chiaramoni, N. S., Pecuch, K. M., & Alonso, S. D. V. (2004) · Drug Delivery · doi:10.1080/10717540490280769 · Cited by 131 · see citing works

Trastuzumab

Plosker, G. L., & Keam, S. J. (2006) · Drugs · doi:10.2165/00003495-200666040-00005 · Cited by 126 · see citing works

Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): Phase I study

Stathopoulos, G. P., Boulikas, T., Vougiouka, M., et al. (2005) · Oncology Reports · doi:10.3892/or.13.4.589 · Cited by 126 · see citing works

Systemic Lipoplatin infusion results in preferential tumor uptake in human studies.

Boulikas, T., Stathopoulos, G. P., Volakakis, N., et al. (2005) · PubMed · Cited by 125 · see citing works

Polymeric Contrast Agents for Medical Imaging

Torchilin, V. P. (2000) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201003378960 · Cited by 125 · see citing works

Phase I Trial of Intrathecal Liposomal Cytarabine in Children With Neoplastic Meningitis

Bomgaars, L. R., Geyer, J. R., Franklin, J. C., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.01.046 · Cited by 124 · see citing works

Controlled destabilization of a liposomal drug delivery system enhances mitoxantrone antitumor activity

Adlakha-Hutcheon, G., Bally, M. B., Shew, C. R., & Madden, T. D. (1999) · Nature Biotechnology · doi:10.1038/11710 · Cited by 122 · see citing works

Surface-associated serum proteins inhibit the uptake of phosphatidylserine and poly(ethylene glycol) liposomes by mouse macrophages

Johnstone, S. A., Masin, D., Mayer, L. D., & Bally, M. B. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00292-9 · Cited by 120 · see citing works

Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine

Jaeckle, K. A., Phuphanich, S., van den Bent, M. J., et al. (2001) · British Journal of Cancer · doi:10.1054/bjoc.2000.1574 · Cited by 120 · see citing works

Influence of dose on liposome clearance: critical role of blood proteins

Oja, C. D., Semple, S. C., Chonn, A., & Cullis, P. R. (1996) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(96)00003-x · Cited by 119 · see citing works

VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo studies

Dagar, S. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00242-6 · Cited by 118 · see citing works

Lipid based particulate formulations for the delivery of antigen

Copland, M. J., Rades, T., Davies, N. M., et al. (2005) · Immunology and Cell Biology · doi:10.1111/j.1440-1711.2005.01315.x · Cited by 116 · see citing works

Immunotherapy with monomethoxypolyethylene glycol modified allergens.

Dreborg, S. K. G., & Akerblom, E. B. (1990) · PubMed · Cited by 114 · see citing works

Intravenous administration of superoxide dismutase entrapped in long circulating liposomes

Corvo, M. L., Boerman, O. C., Oyen, W. J. G., van Bloois, L., Cruz, M. E. M., Crommelin, D. J. A., & Storm, G. (1999) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(99)00081-4 · Cited by 110 · see citing works

Lymphatic Uptake and Biodistribution of Liposomes After Subcutaneous Injection: III. Influence of Surface Modification with Poly(ethyleneglycol)

Oussoren, C., & Storm, G. (1997) · Pharmaceutical Research · doi:10.1023/a:1012145410859 · Cited by 102 · see citing works

Contribution of complement system on destabilization of liposomes composed of hydrogenated egg phosphatidylcholine in rat fresh plasma

Funato, K., Yoda, R., & Kiwada, H. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90087-3 · Cited by 102 · see citing works

Water insoluble and soluble lipids for gene delivery

Mahato, R. I. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.12.005 · Cited by 101 · see citing works

Optimization and Characterization of a Sphingomyelin/Cholesterol Liposome Formulation of Vinorelbine with Promising Antitumor Activity

Semple, S. C., Leone, R., Wang, J., Leng, E. C., Klimuk, S. K., Eisenhardt, M. L., Yuan, Z.-N., Edwards, K., Maurer, N., Hope, M. J., et al. (2005) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20332 · Cited by 101 · see citing works

Biodistribution and pharmacokinetics of 111In-DTPA-labelled pegylated liposomes in a human tumour xenograft model: implications for novel targeting strategies

Harrington, K. J., Rowlinson‐Busza, G., Syrigos, K. N., et al. (2000) · British Journal of Cancer · doi:10.1054/bjoc.1999.1232 · Cited by 97 · see citing works

Transfer of Lipophilic Markers from PLGA and Polystyrene Nanoparticles to Caco-2 Monolayers Mimics Particle Uptake

Pietzonka, P., Rothen‐Rutishauser, B., Langguth, P., Wunderli‐Allenspach, H., Walter, E., & Merkle, H. P. (2002) · Pharmaceutical Research · doi:10.1023/a:1015393710253 · Cited by 95 · see citing works

Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice.

Sugano, M., Egilmez, N. K., Yokota, S. J., et al. (2000) · PubMed · Cited by 93 · see citing works

POLY(HPMA)-COATED LIPOSOMES DEMONSTRATE PROLONGED CIRCULATION IN MICE

Whiteman, K. R., Šubr, V., Ulbrich, K., & Torchilin, V. P. (2001) · Journal of Liposome Research · doi:10.1081/lpr-100108459 · Cited by 93 · see citing works

Phosphatidyl polyglycerols prolong liposome circulation in vivo

Maruyama, K., Okuizumi, S., Ishida, O., YAMAUCHI, H., KIKUCHI, H., & Iwatsuru, M. (1994) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(94)90407-3 · Cited by 92 · see citing works

Influence of tumour size on uptake of111In-DTPA-labelled pegylated liposomes in a human tumour xenograft model

Harrington, K. J., Rowlinson‐Busza, G., Syrigos, K. N., et al. (2000) · British Journal of Cancer · doi:10.1054/bjoc.2000.1320 · Cited by 91 · see citing works

A Novel Peptide Specifically Binding to Nasopharyngeal Carcinoma For Targeted Drug Delivery

Lee, T.-Y., Wu, H., Tseng, Y., & Lin, C. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1948 · Cited by 91 · see citing works

Mechanistic study of the uptake of wheat germ agglutinin-conjugated PLGA nanoparticles by A549 cells

Mo, Y., & Lim, L. Y. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10507 · Cited by 91 · see citing works

HER-2/neu Status Is a Determinant of Mammary Aromatase Activity In vivo: Evidence for a Cyclooxygenase-2-Dependent Mechanism

Subbaramaiah, K., Howe, L. R., Port, E. R., Brogi, E., Fishman, J., Liu, C. H., Hla, T., Hudis, C. A., & Dannenberg, A. J. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4076 · Cited by 91 · see citing works

In Vitro Investigation on Poly(lactide)−Tween 80 Copolymer Nanoparticles Fabricated by Dialysis Method for Chemotherapy

Zhang, Z., & Feng, S. (2006) · Biomacromolecules · doi:10.1021/bm050953v · Cited by 88 · see citing works

Preclinical Manufacture of an Anti-HER2 scFv-PEG-DSPE, Liposome-Inserting Conjugate. 1. Gram-Scale Production and Purification

Nellis, D. F., Ekstrom, D. L., Kirpotin, D. B., et al. (2005) · Biotechnology Progress · doi:10.1021/bp049840y · Cited by 88 · see citing works

Preclinical Manufacture of Anti-HER2 Liposome-Inserting, scFv-PEG-Lipid Conjugate. 2. Conjugate Micelle Identity, Purity, Stability, and Potency Analysis

Nellis, D. F., Giardina, S. L., Janini, G. M., Shenoy, S. R., Marks, J. D., Tsai, R. M., Drummond, D. C., Hong, K., Park, J. W., Ouellette, T. F., et al. (2005) · Biotechnology Progress · doi:10.1021/bp049839z · Cited by 85 · see citing works

A phase II study of liposomal lurtotecan (OSI-211) in patients with topotecan resistant ovarian cancer

Seiden, M. V., Muggia, F. M., Astrow, A., Matulonis, U. A., Campos, S., Roche, M. R., Sivret, J., Rusk, J., & Barrett, E. (2004) · Gynecologic Oncology · doi:10.1016/j.ygyno.2003.12.037 · Cited by 84 · see citing works

Clinical aspects of drug delivery to tumors

Au, J. L. ‐., Jang, S. H., & Wientjes, M. G. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00488-6 · Cited by 84 · see citing works

Pharmacokinetics of intravenously administered liposomal all-trans-retinoic acid (ATRA) and orally administered ATRA in healthy volunteers.

Özpolat, B., Lopez‐Berestein, G., Adamson, P. C., Fu, C. J., & Williams, A. H. (2003) · PubMed · Cited by 81 · see citing works

Nanoparticles of poly(<scp>D</scp>,<scp>L</scp>‐lactide)/methoxy poly(ethylene glycol)‐poly(<scp>D</scp>,<scp>L</scp>‐lactide) blends for controlled release of paclitaxel

Dong, Y., & Feng, S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30684 · Cited by 81 · see citing works

Phase II Study of a Liposome-Entrapped Cisplatin Analog (L-NDDP) Administered Intrapleurally and Pathologic Response Rates in Patients With Malignant Pleural Mesothelioma

Lu, C. S., Pérez-Soler, R., Piperdi, B., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.00.802 · Cited by 80 · see citing works

Anti‐neovascular therapy by liposomal drug targeted to membrane type‐1 matrix metalloproteinase

Kondo, M., Asai, T., Katanasaka, Y., Sadzuka, Y., Tsukada, H., Ogino, K., Taki, T., Baba, K., & Oku, N. (2003) · International Journal of Cancer · doi:10.1002/ijc.11526 · Cited by 79 · see citing works

The role of the liposomal anthracyclines and other systemic therapies in the management of advanced breast cancer

Robert, N. J., Vogel, C. L., Henderson, I. C., et al. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.09.018 · Cited by 78 · see citing works

Uptake and Intracellular Processing of Targeted and Nontargeted Liposomes by Rat Kupffer Cells In Vivo and In Vitroa

Scherphof, G. L., DIJKSTRA, J., Spanjer, H. H., DERKSEN, J. T. P., & Roerdink, F. H. (1985) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1985.tb18414.x · Cited by 76 · see citing works

Depression after successful treatment for nonsmall cell lung carcinoma

Uchitomi, Y., Mikami, I., Kugaya, A., Akizuki, N., Nagai, K., Nishiwaki, Y., Akechi, T., & Okamura, H. (2000) · Cancer · doi:10.1002/1097-0142(20000901)89:5 · Cited by 75 · see citing works

CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome-positive acute lymphoblastic leukemia cells

Harata, M. (2004) · Blood · doi:10.1182/blood-2004-02-0588 · Cited by 75 · see citing works

Poly(ethylene glycol): Protein-repulsive or albumin-compatible?

Vert, M., & Domurado, D. (2000) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856200744345 · Cited by 74 · see citing works

Antitumor effect of MCC‐465, pegylated liposomal doxorubicin tagged with newly developed monoclonal antibody GAH, in colorectal cancer xenografts

Hamaguchi, T., Matsumura, Y., Nakanishi, Y., et al. (2004) · Cancer Science · doi:10.1111/j.1349-7006.2004.tb02495.x · Cited by 72 · see citing works

Cellular Trafficking and Cytotoxicity of Anti-Cd19-Targeted Liposomal Doxorubicin in B Lymphoma Cells

de Menezes, D. E. L., Kirchmeier, M. J., Gagné, J.-F., et al. (1999) · Journal of Liposome Research · doi:10.3109/08982109909024786 · Cited by 71 · see citing works

Haloperidol-associated Stealth Liposomes

Mukherjee, A., Prasad, T. K., Rao, N. M., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409723200 · Cited by 70 · see citing works

Macrophage Specific Drug Delivery in Experimental Leishmaniasis

Basu, M. K., & Lala, S. (2004) · Current Molecular Medicine · doi:10.2174/1566524043360186 · Cited by 68 · see citing works

Lipid-based formulations of amphotericin B

Veerareddy, P. R., & Vobalaboina, V. (2004) · Drugs of today · doi:10.1358/dot.2004.40.2.799425 · Cited by 68 · see citing works

Therapeutic Effect of Fe2O3 Nanoparticles Combined with Magnetic Fluid Hyperthermia on Cultured Liver Cancer Cells and Xenograft Liver Cancers

Yan, S., Zhang, D., Gu, N., et al. (2005) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2005.219 · Cited by 65 · see citing works

Design and Characterization of Liposomes Containing Long-Chain N-AcylPEs for Brain Delivery: Penetration of Liposomes Incorporating GM1 into the Rat Brain

Mora, M., Sagristá, M. L., Trombetta, D., et al. (2002) · Pharmaceutical Research · doi:10.1023/a:1020440229102 · Cited by 60 · see citing works

Preparation, Characterization, and Stability of Liposome-Based Formulations of Mitoxantrone

Ugwu, S. O., Zhang, A. W., Parmar, M. M., et al. (2005) · Drug Development and Industrial Pharmacy · doi:10.1081/ddc-200047850 · Cited by 59 · see citing works

Randomized Trial of Two Intravenous Schedules of the Topoisomerase I Inhibitor Liposomal Lurtotecan in Women With Relapsed Epithelial Ovarian Cancer: A Trial of the National Cancer Institute of Canada Clinical Trials Group

Dark, G. G., Calvert, A. H., Grimshaw, R. N., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.02.028 · Cited by 59 · see citing works

A novel influenza subunit vaccine composed of liposome-encapsulated haemagglutinin/neuraminidase and IL-2 or GM-CSF. I. Vaccine characterization and efficacy studies in mice

Babai, I., Samira, S., Barenholz, Y., et al. (1999) · Vaccine · doi:10.1016/s0264-410x(98)00346-6 · Cited by 58 · see citing works

Design and tumor targeting of anthracyclines able to overcome multidrug resistance: A double-advantage approach

Priebe, W., & Pérez-Soler, R. (1993) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(93)90007-z · Cited by 58 · see citing works

v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells

Masumoto, N., Nakano, S., Fujishima, H., Kohno, K., & Niho, Y. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990301)80:5 · Cited by 57 · see citing works

Liposome-induced activation of the classical complement pathway does not require immunoglobulin

Marjan, J. M. J., Xie, Z., & Devine, D. V. (1994) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)90140-6 · Cited by 55 · see citing works

Novel powder formulations for controlled delivery of poorly soluble anticancer drug: Application and investigation of TPGS and PEG in spray-dried particulate system

Mu, L., Teo, M. Y. B., Ning, H.-Z., et al. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.12.023 · Cited by 55 · see citing works

Poly (Lactide-co-Glycolide) Nanoparticles Containing Coumarin-6 for Suppository Delivery: In Vitro Release Profile and In Vivo Tissue Distribution

Eley, J. G., Pujari, V. D., & McLane, J. S. (2004) · Drug Delivery · doi:10.1080/10717540490467384 · Cited by 55 · see citing works

Non‐Viral Vector as Vaccine Carrier

Chen, W. C., & Huang, L. (2005) · Advances in genetics · doi:10.1016/s0065-2660(05)54013-6 · Cited by 54 · see citing works

Particulate delivery systems for biodefense subunit vaccines

Bramwell, V. W., Eyles, J. E., & Alpar, H. O. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.01.010 · Cited by 52 · see citing works

Folate Receptor-Mediated Targeting of Liposomal Drugs to Cancer Cells

Stephenson, S. M., Low, P. S., & Lee, R. J. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)87003-4 · Cited by 50 · see citing works

Polymeric nanospheres fabricated with natural emulsifiers for clinical administration of an anticancer drug paclitaxel (Taxol®)

Feng, S., Li, M., Chen, B., et al. (2002) · Materials Science and Engineering C · doi:10.1016/s0928-4931(02)00017-6 · Cited by 50 · see citing works

Interaction pharmacokinetics of pegylated liposomal doxorubicin (Caelyx) on coadministration with paclitaxel or docetaxel

Briasoulis, E. C., Karavasilis, V., Tzamakou, E., et al. (2004) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-003-0750-5 · Cited by 49 · see citing works

First line therapy with paclitaxel (Taxol®) and pegylated liposomal doxorubicin (Caelyx®) in patients with metastatic breast cancer: a multicentre phase II study

Vorobiof, D., Rapoport, B. L., Chasen, M. R., et al. (2004) · The Breast · doi:10.1016/j.breast.2004.01.006 · Cited by 48 · see citing works

Biodistribution of pH-responsive liposomes for MRI and a novel approach to improve the pH-responsiveness

Løkling, K., Fossheim, S. L., Klaveness, J., & Skurtveit, R. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.04.015 · Cited by 47 · see citing works

Effects of sialic acid derivative on long circulation time and tumor concentration of liposomes

Yamauchi, H., Yano, T., Kato, T., et al. (1995) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(94)00188-b · Cited by 47 · see citing works

Preparation of DHAQ-loaded mPEG-PLGA-mPEG nanoparticles and evaluation of drug release behaviors in vitro/in vivo

Duan, Y., Sun, X., Gong, T., Wang, Q., & Zhang, Z. (2006) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-006-8933-3 · Cited by 46 · see citing works

IgG2a induced by interleukin (IL) 12-producing tumor cell vaccines but not IgG1 induced by IL-4 vaccine is associated with the eradication of experimental metastases.

Rodolfo, M., Melani, C. C., Zilocchi, C., et al. (1998) · PubMed · Cited by 43 · see citing works

Transfection properties of stabilized plasmid–lipid particles containing cationic PEG lipids

Palmer, L., Chen, T., Lam, A. M. I., et al. (2003) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(03)00058-0 · Cited by 43 · see citing works

Some negatively charged phospholipid derivatives prolong the liposome circulation in vivo

Park, Y. S., Maruyama, K., & Huang, L. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90034-j · Cited by 43 · see citing works

Antiactin-Targeted Immunoliposomes Ameliorate Tissue Plasminogen Activator-Induced Hemorrhage after Focal Embolic Stroke

Asahi, M., Rammohan, R., Sumii, T., Wang, X., Pauw, R. J., Weissig, V., Torchilin, V. P., & Lo, E. H. (2003) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/01.wcb.0000072570.46552.df · Cited by 42 · see citing works

Folate receptor-targeted liposomes as possible delivery vehicles for boron neutron capture therapy.

Stephenson, S. M., Yang, W., Stevens, P. J., Tjarks, W., Barth, R. F., & Lee, R. J. (2003) · PubMed · Cited by 42 · see citing works

Hydrolysis of lactic acid based poly(ester-urethane)s

Hiltunen, K., Tuominen, J. U., & Seppälä, J. V. (1998) · Polymer International · doi:10.1002/(sici)1097-0126(1998100)47:2 · Cited by 33 · see citing works

Liposomes: Structure, composition, types, and clinical applications

Nsairat, H., Khater, D., Sayed, U., Odeh, F., Al Bawab, A., & Alshaer, W. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09394 · Cited by 1,561 · see citing works

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

Akinc, A., Querbes, W., De, S., Qin, J., Frank-Kamenetsky, M., Jayaprakash, K. N., Jayaraman, M., Rajeev, K. G., Cantley, W. L., Dorkin, J. R., et al. (2010) · Molecular Therapy · doi:10.1038/mt.2010.85 · Cited by 1,261 · see citing works

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review

Kanamala, M., Wilson, W. R., Yang, M., Palmer, B. D., & Wu, Z. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.01.061 · Cited by 1,004 · see citing works

Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine

Lombardo, D., Kiselev, M. A., & Caccamo, M. T. (2019) · Journal of Nanomaterials · doi:10.1155/2019/3702518 · Cited by 864 · see citing works

Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers

Fang, J., Islam, W., & Maeda, H. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.005 · Cited by 757 · see citing works

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works

Hydration lubrication

Klein, J. (2013) · Friction · doi:10.1007/s40544-013-0001-7 · Cited by 567 · see citing works

Polymeric micelles drug delivery system in oncology

Gong, J., Chen, M., Zheng, Y., Wang, S., & Wang, Y. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.12.012 · Cited by 570 · see citing works

Iron Oxide Nanoparticles for Magnetically-Guided and Magnetically-Responsive Drug Delivery

Estelrich, J., Escribano, E., Queralt, J., & Busquets, M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16048070 · Cited by 532 · see citing works

Light‐sensitive Intelligent Drug Delivery Systems^†

Alvarez‐Lorenzo, C., Bromberg, L., & Concheiro, A. (2009) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2008.00530.x · Cited by 519 · see citing works

Liposomes for use in gene delivery

Balazs, D. A., & Godbey, W. (2011) · Journal of Drug Delivery · doi:10.1155/2011/326497 · Cited by 441 · see citing works

Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems

Guan, S., & Rosenecker, J. (2017) · Gene Therapy · doi:10.1038/gt.2017.5 · Cited by 389 · see citing works

Metal Drugs and the Anticancer Immune Response

Englinger, B., Pirker, C., Heffeter, P., Terenzi, A., Kowol, C. R., Keppler, B. K., & Berger, W. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00396 · Cited by 355 · see citing works

Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for<i>in Vivo</i>Targeting of Tumor Hypoxia

Poon, Z., Chang, D., Zhao, X., & Hammond, P. T. (2011) · ACS Nano · doi:10.1021/nn200876f · Cited by 343 · see citing works

Multifunctional poly(D,L-lactide-co-glycolide)/ montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer

Sun, B., Ranganathan, B., & Feng, S.-S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.09.038 · Cited by 274 · see citing works

Metallodrugs in cancer nanomedicine

Peña, Q., Wang, A., Zaremba, O., Shi, Y., Scheeren, H. W., Metselaar, J. M., Kiessling, F., Pallares, R. M., Wuttke, S., & Lammers, T. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00468a · Cited by 259 · see citing works

Co-delivery of chemotherapeutics and proteins for synergistic therapy

He, C., Tang, Z., Tian, H., & Chen, X. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.10.021 · Cited by 231 · see citing works

Lipid nanoparticle-mediated efficient delivery of CRISPR/Cas9 for tumor therapy

Zhang, L., Wang, P., Feng, Q., Wang, N., Chen, Z., Huang, Y., Zheng, W., & Jiang, X. (2017) · NPG Asia Materials · doi:10.1038/am.2017.185 · Cited by 218 · see citing works

The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes

Kierstead, P. H., Okochi, H., Venditto, V. J., Chuong, T. C., Kivimae, S., Fréchet, J. M. J., & Szoka, F. C. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.06.023 · Cited by 210 · see citing works

Lipid-based nanoparticle formulations for small molecules and RNA drugs

Ickenstein, L. M., & Garidel, P. (2019) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2019.1669558 · Cited by 193 · see citing works

Targeted delivery of paclitaxel using folate-decorated poly(lactide)-vitamin E TPGS nanoparticles

Pan, J., & Feng, S.-S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.02.020 · Cited by 187 · see citing works

Role of the methoxy group in immune responses to mPEG-protein conjugates

Sherman, M. R., Williams, L. D., Sobczyk, M. A., Michaels, S. J., & Saifer, M. G. P. (2012) · Bioconjugate Chemistry · doi:10.1021/bc200551b · Cited by 185 · see citing works

Biomaterials for mRNA delivery

Islam, M. A., Reesor, E. K. G., Xu, Y., Zope, H. R., Zetter, B. R., & Shi, J. (2015) · Biomaterials Science · doi:10.1039/c5bm00198f · Cited by 176 · see citing works

Biomembrane-based nanostructures for cancer targeting and therapy: From synthetic liposomes to natural biomembranes and membrane-vesicles

Wang, J., Zhu, M., & Nie, G. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113974 · Cited by 153 · see citing works

Targeted mRNA Therapy for Ornithine Transcarbamylase Deficiency

Prieve, M. G., Harvie, P., Monahan, S. D., Roy, D., Li, A. G., Blevins, T. L., Paschal, A. E., Waldheim, M., Bell, E. C., Galperin, A., et al. (2018) · Molecular Therapy · doi:10.1016/j.ymthe.2017.12.024 · Cited by 145 · see citing works

Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading

Sutaria, D. S., Badawi, M., Phelps, M. A., & Schmittgen, T. D. (2017) · Pharmaceutical Research · doi:10.1007/s11095-017-2123-5 · Cited by 140 · see citing works

PEGylated nanomedicines: recent progress and remaining concerns

Vllasaliu, D., Fowler, R., & Stolnik, S. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2014.866651 · Cited by 137 · see citing works

Liposomal delivery of proteins and peptides

Swaminathan, J., & Ehrhardt, C. (2012) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2012.735658 · Cited by 135 · see citing works

Clinically approved liposomal nanomedicines: lessons learned from the biomolecular corona

Caracciolo, G. (2018) · Nanoscale · doi:10.1039/c7nr07450f · Cited by 106 · see citing works

Lipid Nanoparticles for Ocular Gene Delivery

Wang, Y., Rajala, A., & Rajala, R. (2015) · Journal of Functional Biomaterials · doi:10.3390/jfb6020379 · Cited by 93 · see citing works

Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery

Wang, Y., van Steenbergen, M. J., Beztsinna, N., Shi, Y., Lammers, T., van Nostrum, C. F., & Hennink, W. E. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.013 · Cited by 66 · see citing works

Ligand-functionalized nanoliposomes for targeted delivery of galantamine

Mufamadi, M. S., Choonara, Y. E., Kumar, P., Modi, G., Naidoo, D., van Vuuren, S., Ndesendo, V. M. K., Toit, L. C. D., Iyuke, S. E., & Pillay, V. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.03.037 · Cited by 51 · see citing works

Biocompatible Nanovesicular Drug Delivery Systems with Targeting Potential for Autoimmune Diseases

Neupane, Y. R., Mahtab, A., Siddiqui, L., Singh, A., Gautam, N., Rabbani, S. A., Goel, H., & Talegaonkar, S. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200523174108 · Cited by 21 · see citing works

The Role of the Reticuloendothelial System in Viral Hepatitis

Paronetto, F. (1988) · Infection · doi:10.1007/978-1-4899-3748-3_11 · Cited by 1 · see citing works

Complement Dependent and Independent Liposome Uptake by Peritoneal Macrophages: Cholesterol Content Dependency.

Tran Minh, H. O. N. G., Harashima, H., & Kiwada, H. (1998) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.21.969 · Cited by 17 · see citing works

Effect of liposome type and membrane fluidity on drug–membrane partitioning analyzed by immobilized liposome chromatography

Liu, X.-Y., Yang, Q. K., Kamo, N., et al. (2001) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)01266-8 · Cited by 68 · see citing works

Rates of Systemic Degradation and Reticuloendothelial System (RES) Uptake of Thermosensitive Liposome Encapsulating Cisplatin in Rats

Iga, K., Ogawa, Y., & Toguchi, H. (1993) · Pharmaceutical Research · doi:10.1023/a:1018925931294 · Cited by 5 · see citing works

Studies on liposome-encapsulated carboquone. II. Effect of liposomal encapsulation of carboquone on distribution and clearance in animals.

Hisaoka, M., Tsukada, K., & Morioka, T. (1982) · Journal of Pharmacobio-Dynamics · doi:10.1248/bpb1978.5.18 · Cited by 5 · see citing works