The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells
Open accessAbstract
A shuttle system has been developed to genetically encode unnatural amino acids in mammalian cells using aminoacyl‐tRNA synthetases (aaRSs) evolved in E. coli. A pyrrolysyl‐tRNA synthetase (PylRS) mutant was evolved in E. coli that selectively aminoacylates a cognate nonsense suppressor tRNA with a photocaged lysine derivative. Transfer of this orthogonal tRNA–aaRS pair into mammalian cells made possible the selective incorporation of this unnatural amino acid into proteins. magnified image
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Cites
Expanding the Genetic Code of Escherichia coli
Wang, L., Brock, A., Herberich, B., & Schultz, P. G. (2001) · Science · doi:10.1126/science.1060077 · Cited by 1,499
Self-citationBiologically Active Molecules with a “Light Switch”
Mayer, G., & Heckel, A. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200600387 · Cited by 1,119
Photoremovable protecting groups: reaction mechanisms and applications
Pelliccioli, A. P., & Wirz, J. (2002) · Photochemical & Photobiological Sciences · doi:10.1039/b200777k · Cited by 671
Pyrrolysine Encoded by UAG in Archaea: Charging of a UAG-Decoding Specialized tRNA
Srinivasan, G., James, C. M., & Krzycki, J. A. (2002) · Science · doi:10.1126/science.1069588 · Cited by 639
Genetically encoding Nε-acetyllysine in recombinant proteins
Neumann, H., Peak-Chew, S. Y., & Chin, J. W. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.73 · Cited by 592
Wang, L., Xie, J., & Schultz, P. G. (2006) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.35.101105.121507 · Cited by 582
Self-citationA chemical toolkit for proteins — an expanded genetic code
Xie, J., & Schultz, P. G. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2005 · Cited by 408
Self-citationGenetic incorporation of unnatural amino acids into proteins in mammalian cells
Liu, W., Brock, A., Chen, S., Chen, S., & Schultz, P. G. (2007) · Nature Methods · doi:10.1038/nmeth1016 · Cited by 373
Self-citationYanagisawa, T., Ishii, R., Fukunaga, R., Kobayashi, T., Sakamoto, K., & Yokoyama, S. (2008) · Chemistry & Biology · doi:10.1016/j.chembiol.2008.10.004 · Cited by 336
Efficient incorporation of unnatural amino acids into proteins in Escherichia coli
Ryu, Y., & Schultz, P. G. (2006) · Nature Methods · doi:10.1038/nmeth864 · Cited by 315
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Cited by
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Self-citationReetz, M. T. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201000826 · Cited by 538
Expanding and Reprogramming the Genetic Code of Cells and Animals
Chin, J. W. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035737 · Cited by 476
Semisynthetic DNA–Protein Conjugates for Biosensing and Nanofabrication
Niemeyer, C. M. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200904930 · Cited by 369
Schmied, W. H., Elsässer, S. J., Uttamapinant, C., & Chin, J. W. (2014) · Journal of the American Chemical Society · doi:10.1021/ja5069728 · Cited by 270
Metadata
- Authors
- Chen, P. R., Groff, D., Guo, J., Ou, W., Cellitti, S., Geierstanger, B. H., & Schultz, P. G.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2009-05-12
- Volume
- 48
- Issue
- 22
- Pages
- 4052-4055
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W4231832388
- Cited by
- 269
- References
- 24
- FWCI
- 8.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Chen, P. R., Groff, D., Guo, J., Ou, W., Cellitti, S., Geierstanger, B. H., & Schultz, P. G. (2009). A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200900683
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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