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Cited by 369

The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.

Semisynthetic DNA–Protein Conjugates for Biosensing and Nanofabrication

Niemeyer, Christof M.·2010·Angewandte Chemie International Edition

Abstract

Conjugation with artificial nucleic acids allows proteins to be modified with a synthetically accessible, robust tag. This attachment is addressable in a highly specific manner by means of molecular recognition events, such as Watson–Crick hybridization. Such DNA–protein conjugates, with their combined properties, have a broad range of applications, such as in high‐performance biomedical diagnostic assays, fundamental research on molecular recognition, and the synthesis of DNA nanostructures. This Review surveys current approaches to generate DNA–protein conjugates as well as recent advances in their applications. For example, DNA–protein conjugates have been assembled into model systems for the investigation of catalytic cascade reactions and light‐harvesting devices. Such hybrid conjugates are also used for the biofunctionalization of planar surfaces for micro‐ and nanoarrays, and for decorating inorganic nanoparticles to enable applications in sensing, materials science, and catalysis.

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Metadata

Authors
Niemeyer, C. M.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2010-02
Volume
49
Issue
7
Pages
1200-1216
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2156578843
Cited by
369
References
159
FWCI
13.94
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Semisynthetic DNA–Protein Conjugates for Biosensing and Nanofabrication. https://app.cochat.ai/papers/10.1002/anie.200904930
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Niemeyer, C. M. (2010). Semisynthetic DNA–Protein Conjugates for Biosensing and Nanofabrication. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200904930

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