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In Vivo, In Situ Tissue Analysis Using Rapid Evaporative Ionization Mass Spectrometry
Abstract
Beam me up: A novel mass spectrometric ionization technique based on rapid evaporation of biological tissues (see picture) can be used to analyze vital tissues during surgical intervention as well as for processed tissue specimens. A tissue identification system based on principal-component analysis was developed. The method differentiates malignant tumor cells from the surrounding healthy tissue.
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Citations
Cited by
Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry
Balog, J., Sasi-Szabó, L., Kinross, J., Lewis, M. R., Muirhead, L. J., Veselkov, K., Mirnezami, R., Dezső, B., Damjanovich, L., Darzi, A., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005623 · Cited by 608
Self-citationAmbient Sampling/Ionization Mass Spectrometry: Applications and Current Trends
Harris, G. A., Galhena, A. S., & Fernández, F. M. (2011) · Analytical Chemistry · doi:10.1021/ac200918u · Cited by 527
Mass Spectrometry: Recent Advances in Direct Open Air Surface Sampling/Ionization
Monge, M. E., Harris, G. A., Dwivedi, P., & Fernández, F. M. (2013) · Chemical Reviews · doi:10.1021/cr300309q · Cited by 476
Zhang, J., Rector, J., Lin, J. Q., Young, J. H., Sans, M., Katta, N., Giese, N., Yu, W., Nagi, C., Suliburk, J., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aan3968 · Cited by 406
Advances in Mass Spectrometry for Lipidomics
Blanksby, S. J., & Mitchell, T. W. (2010) · Annual Review of Analytical Chemistry · doi:10.1146/annurev.anchem.111808.073705 · Cited by 366
Metadata
- Authors
- Schäfer, K., Dénes, J., Albrecht, K., Szaniszló, T., Balog, J., Skoumal, R., Katona, M., Tóth, M., Balogh, L., & Takáts, Z.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2009-10-13
- Volume
- 48
- Issue
- 44
- Pages
- 8240-8242
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W1982026768
- Cited by
- 334
- References
- 0
- FWCI
- 4.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: In Vivo, In Situ Tissue Analysis Using Rapid Evaporative Ionization Mass Spectrometry. https://app.cochat.ai/papers/10.1002/anie.200902546
- The paper
- Schäfer, K., Dénes, J., Albrecht, K., Szaniszló, T., Balog, J., Skoumal, R., Katona, M., Tóth, M., Balogh, L., & Takáts, Z. (2009). In Vivo, In Situ Tissue Analysis Using Rapid Evaporative Ionization Mass Spectrometry. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200902546
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
