The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis
Abstract
The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales—from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.
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Citations
Cites
Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices
Lee, J. N., Park, C., & Whitesides, G. M. (2003) · Analytical Chemistry · doi:10.1021/ac0346712 · Cited by 2,643
Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents
Song, H., & Ismagilov, R. F. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0354566 · Cited by 693
Microchemical systems for continuous-flow synthesis
Hartman, R. L., & Jensen, K. F. (2009) · Lab on a Chip · doi:10.1039/b906343a · Cited by 508
Self-citationKreutz, J. E., Shukhaev, A., Du, W., Druskin, S., Daugulis, O., & Ismagilov, R. F. (2010) · Journal of the American Chemical Society · doi:10.1021/ja909853x · Cited by 126
Cited by
The Hitchhiker’s Guide to Flow Chemistry
Plutschack, M. B., Pieber, B., Gilmore, K., & Seeberger, P. H. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00183 · Cited by 1,995
A robotic platform for flow synthesis of organic compounds informed by AI planning
Coley, C. W., Thomas, D. A., Lummiss, J. A. M., Jaworski, J. N., Breen, C. P., Schultz, V., Hart, T., Fishman, J. S., Rogers, L., Gao, H., et al. (2019) · Science · doi:10.1126/science.aax1566 · Cited by 1,052
Self-citationSchneider, G. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.232 · Cited by 910
Tay, N. E. S., Lehnherr, D., & Rovis, T. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00384 · Cited by 518
A field guide to flow chemistry for synthetic organic chemists
Capaldo, L., Wen, Z., & Noël, T. (2023) · Chemical Science · doi:10.1039/d3sc00992k · Cited by 402
Metadata
- Authors
- Hartman, R. L., McMullen, J. P., & Jensen, K. F.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2011-06-27
- Volume
- 50
- Issue
- 33
- Pages
- 7502-7519
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2146993554
- Cited by
- 999
- References
- 4
- FWCI
- 44.30
- Type
- journal article
- Language
- en
- Open access
- closed
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