The DOI matches its Crossref record; 260 of the 260 references it cites were found in a registry or an index.
Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures
Abstract
This review describes a multidimensional treatment of molecular recognition phenomena involving aromatic rings in chemical and biological systems. It summarizes new results reported since the appearance of an earlier review in 2003 in host–guest chemistry, biological affinity assays and biostructural analysis, data base mining in the Cambridge Structural Database (CSD) and the Protein Data Bank (PDB), and advanced computational studies. Topics addressed are arene–arene, perfluoroarene–arene, S⋅⋅⋅aromatic, cation–π, and anion–π interactions, as well as hydrogen bonding to π systems. The generated knowledge benefits, in particular, structure‐based hit‐to‐lead development and lead optimization both in the pharmaceutical and in the crop protection industry. It equally facilitates the development of new advanced materials and supramolecular systems, and should inspire further utilization of interactions with aromatic rings to control the stereochemical outcome of synthetic transformations.
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Exhaustive Fluorine Scanning toward Potent p53–Mdm2 Antagonists
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Metadata
- Authors
- Salonen, L. M., Ellermann, M., & Diederich, F.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2011-04-28
- Volume
- 50
- Issue
- 21
- Pages
- 4808-4842
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2117569373
- Cited by
- 1,539
- References
- 260
- FWCI
- 93.56
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
