The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Highly Fluorescent Semiconducting Polymer Dots for Biology and Medicine
Open accessAbstract
In recent years, semiconducting polymer nanoparticles have attracted considerable attention because of their outstanding characteristics as fluorescent probes. These nanoparticles, which primarily consist of π‐conjugated polymers and are called polymer dots (Pdots) when they exhibit small particle size and high brightness, have demonstrated utility in a wide range of applications such as fluorescence imaging and biosensing. In this review, we summarize recent findings of the photophysical properties of Pdots which speak to the merits of these entities as fluorescent labels. This review also highlights the surface functionalization and biomolecular conjugation of Pdots, and their applications in cellular labeling, in vivo imaging, single‐particle tracking, biosensing, and drug delivery. We discuss the relationship between the physical properties and performance, and evaluate the merits and limitations of the Pdot probes for certain imaging tasks and fluorescence assays. We also tackle the current challenges of Pdots and share our perspective on the future directions of the field.
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Cites
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Multicolor Fluorescent Semiconducting Polymer Dots with Narrow Emissions and High Brightness
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Cited by
Zhu, S., Song, Y., Zhao, X., Shao, J., Zhang, J., & Yang, B. (2015) · Nano Research · doi:10.1007/s12274-014-0644-3 · Cited by 2,781
Fluorescent Polymer Nanoparticles Based on Dyes: Seeking Brighter Tools for Bioimaging
Reisch, A., & Klymchenko, A. S. (2016) · Small · doi:10.1002/smll.201503396 · Cited by 634
Ultralong Phosphorescence of Water‐Soluble Organic Nanoparticles for In Vivo Afterglow Imaging
Zhen, X., Tao, Y., An, Z., Chen, P., Xu, C., Chen, R., Huang, W., & Pu, K. (2017) · Advanced Materials · doi:10.1002/adma.201606665 · Cited by 602
Molecularly Imprinted Polymers: Antibody Mimics for Bioimaging and Therapy
Haupt, K., Medina Rangel, P. X., & Bui, B. T. S. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00428 · Cited by 561
Donor Engineering for NIR-II Molecular Fluorophores with Enhanced Fluorescent Performance
Yang, Q., Hu, Z., Zhu, S., Ma, R., Ma, H., Ma, Z., Wan, H., Zhu, T., Jiang, Z., Liu, W., et al. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b10334 · Cited by 554
Metadata
- Authors
- Wu, C., & Chiu, D. T.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2013-01-10
- Volume
- 52
- Issue
- 11
- Pages
- 3086-3109
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2054308157
- Cited by
- 1,101
- References
- 7
- FWCI
- 43.66
- Type
- journal article
- Language
- en
- Open access
- green
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