The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
The Prodrug Platin‐A: Simultaneous Release of Cisplatin and Aspirin
Abstract
Cancer‐associated inflammation induces tumor progression to the metastatic stage, thus indicating that a chemo‐anti‐inflammatory strategy is of interest for the management of aggressive cancers. The platinum(IV) prodrug Platin‐A was designed to release cisplatin and aspirin to ameliorate the nephrotoxicity and ototoxicity caused by cisplatin. Platin‐A exhibited anticancer and anti‐inflammatory properties which are better than a combination of cisplatin and aspirin. These findings highlight the advantages of combining anti‐inflammatory treatment with chemotherapy when both the drugs are delivered in the form of a single prodrug.
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Cites
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Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs
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Prostaglandins and Inflammation
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Structure, Recognition, and Processing of Cisplatin−DNA Adducts
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Dysregulated pH: a perfect storm for cancer progression
Webb, B. A., Chimenti, M., Jacobson, M. P., & Barber, D. L. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3110 · Cited by 2,237
A cytokine-mediated link between innate immunity, inflammation, and cancer
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Inflammation in prostate carcinogenesis
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The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
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Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?
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Platinum(iv) anticancer prodrugs – hypotheses and facts
Gibson, D. (2016) · Dalton Transactions · doi:10.1039/c6dt01414c · Cited by 286
Metallodrugs in cancer nanomedicine
Peña, Q., Wang, A., Zaremba, O., Shi, Y., Scheeren, H. W., Metselaar, J. M., Kiessling, F., Pallares, R. M., Wuttke, S., & Lammers, T. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00468a · Cited by 259
Metadata
- Authors
- Pathak, R. K., Marrache, S., Choi, J. H., Berding, T. B., & Dhar, S.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2014-01-22
- Volume
- 53
- Issue
- 7
- Pages
- 1963-1967
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2114410648
- Cited by
- 255
- References
- 30
- FWCI
- 11.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Prodrug Platin‐A: Simultaneous Release of Cisplatin and Aspirin. https://app.cochat.ai/papers/10.1002/anie.201308899
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- Pathak, R. K., Marrache, S., Choi, J. H., Berding, T. B., & Dhar, S. (2014). The Prodrug Platin‐A: Simultaneous Release of Cisplatin and Aspirin. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201308899
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
