The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Simple Peptide‐Tuned Self‐Assembly of Photosensitizers towards Anticancer Photodynamic Therapy
Open accessAbstract
Peptide‐tuned self‐assembly of functional components offers a strategy towards improved properties and unique functions of materials, but the requirement of many different functions and a lack of understanding of complex structures present a high barrier for applications. Herein, we report a photosensitive drug delivery system for photodynamic therapy (PDT) by a simple dipeptide‐ or amphiphilic amino‐acid‐tuned self‐assembly of photosensitizers (PSs). The assembled nanodrugs exhibit multiple favorable therapeutic features, including tunable size, high loading efficiency, and on‐demand drug release responding to pH, surfactant, and enzyme stimuli, as well as preferable cellular uptake and biodistribution. These features result in greatly enhanced PDT efficacy in vitro and in vivo, leading to almost complete tumor eradication in mice receiving a single drug dose and a single exposure to light.
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Cites
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Cited by
Biomimetic peptide self-assembly for functional materials
Levin, A., Hakala, T. A., Schnaider, L., Bernardes, G. J. L., Gazit, E., & Knowles, T. P. J. (2020) · Nature Reviews Chemistry · doi:10.1038/s41570-020-0215-y · Cited by 853
Rejuvenated Photodynamic Therapy for Bacterial Infections
Jia, Q., Song, Q., Li, P., & Huang, W. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900608 · Cited by 426
Nanoscale metal–organic frameworks for phototherapy of cancer
Lan, G., Ni, K., & Lin, W. (2019) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2017.09.007 · Cited by 420
Supramolecular cancer nanotheranostics
Zhou, J., Rao, L., Yu, G., Cook, T. R., Chen, X., & Huang, F. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00011f · Cited by 411
Catalase-Integrated Hyaluronic Acid as Nanocarriers for Enhanced Photodynamic Therapy in Solid Tumor
Phua, S. Z. F., Yang, G., Lim, W. Q., Verma, A., Chen, H., Thanabalu, T., & Zhao, Y. (2019) · ACS Nano · doi:10.1021/acsnano.9b01087 · Cited by 375
Metadata
- Authors
- Liu, K., Xing, R., Zou, Q., Ma, G., Möhwald, H., & Yan, X.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2016-01-25
- Volume
- 55
- Issue
- 9
- Pages
- 3036-3039
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2270780899
- Cited by
- 503
- References
- 33
- FWCI
- 73.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Liu, K., Xing, R., Zou, Q., Ma, G., Möhwald, H., & Yan, X. (2016). Simple Peptide‐Tuned Self‐Assembly of Photosensitizers towards Anticancer Photodynamic Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201509810
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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