The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Discerning the Chemistry in Individual Organelles with Small‐Molecule Fluorescent Probes
Abstract
Principle has it that even the most advanced super‐resolution microscope would be futile in providing biological insight into subcellular matrices without well‐designed fluorescent tags/probes. Developments in biology have increasingly been boosted by advances of chemistry, with one prominent example being small‐molecule fluorescent probes that not only allow cellular‐level imaging, but also subcellular imaging. A majority, if not all, of the chemical/biological events take place inside cellular organelles, and researchers have been shifting their attention towards these substructures with the help of fluorescence techniques. This Review summarizes the existing fluorescent probes that target chemical/biological events within a single organelle. More importantly, organelle‐anchoring strategies are described and emphasized to inspire the design of new generations of fluorescent probes, before concluding with future prospects on the possible further development of chemical biology.
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Cited by
Zielonka, J., Joseph, J., Sikora, A., Hardy, M., Ouari, O., Vasquez-Vivar, J., Cheng, G., Lopez, M., & Kalyanaraman, B. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00042 · Cited by 1,683
Zhang, Q., Xu, S., Li, M., Wang, Y., Zhang, N., Guan, Y., Chen, M., Chen, C.-F., & Hu, H.-Y. (2019) · Chemical Communications · doi:10.1039/c9cc00898e · Cited by 73
Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells
Benhamou, R. I., Bibi, M., Steinbuch, K. B., Engel, H., Levin, M., Roichman, Y., Berman, J., & Fridman, M. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00339 · Cited by 71
Localizing Antifungal Drugs to the Correct Organelle Can Markedly Enhance their Efficacy
Benhamou, R. I., Bibi, M., Berman, J., & Fridman, M. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201802509 · Cited by 42
Xu, Y., Dou, Y., Li, Q., Ye, H., Li, Y., Qiu, S., Xiong, X., Li, J., & Sun, Y. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215320 · Cited by 39
Metadata
- Authors
- Xu, W., Zeng, Z., Jiang, J., Chang, Y., & Yuan, L.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2016-08-29
- Volume
- 55
- Issue
- 44
- Pages
- 13658-13699
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2512484144
- Cited by
- 808
- References
- 21
- FWCI
- 42.68
- Type
- journal article
- Language
- en
- Open access
- closed
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