The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
A Multinuclear Metal Complex Based DNase‐Mimetic Artificial Enzyme: Matrix Cleavage for Combating Bacterial Biofilms
Abstract
Extracellular DNA (eDNA) is an essential structural component during biofilm formation, including initial bacterial adhesion, subsequent development, and final maturation. Herein, the construction of a DNase‐mimetic artificial enzyme (DMAE) for anti‐biofilm applications is described. By confining passivated gold nanoparticles with multiple cerium(IV) complexes on the surface of colloidal magnetic Fe 3 O 4 /SiO 2 core/shell particles, a robust and recoverable artificial enzyme with DNase‐like activity was obtained, which exhibited high cleavage ability towards both model substrates and eDNA. Compared to the high environmental sensitivity of natural DNase in anti‐biofilm applications, DMAE exhibited a much better operational stability and easier recoverability. When DMAE was coated on substratum surfaces, biofilm formation was inhibited for prolonged periods of time, and the DMAE excelled in the dispersion of established biofilms of various ages. Finally, the presence of DMAE remarkably potentiated the efficiency of traditional antibiotics to kill biofilm‐encased bacteria and eradiate biofilms.
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Extracellular DNA Required for Bacterial Biofilm Formation
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Quantification of biofilm structures by the novel computer program comstat
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Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection
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Self-citationZhang, C., Bu, W., Ni, D., Zhang, S., Li, Q., Yao, Z., Zhang, J., Yao, H., Wang, Z., & Shi, J. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201510031 · Cited by 1,269
Self-citationCatalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes
Lin, Y., Ren, J., & Qu, X. (2014) · Accounts of Chemical Research · doi:10.1021/ar400250z · Cited by 1,252
Self-citationA genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance
Mah, T.-F., Pitts, B., Pellock, B., Walker, G. C., Stewart, P. S., & O'Toole, G. A. (2003) · Nature · doi:10.1038/nature02122 · Cited by 1,190
Intracellular Bacterial Biofilm-Like Pods in Urinary Tract Infections
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d -Amino Acids Trigger Biofilm Disassembly
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Graphene Quantum Dots-Band-Aids Used for Wound Disinfection
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Cited by
Enzyme Mimicry for Combating Bacteria and Biofilms
Chen, Z., Wang, Z., Ren, J., & Qu, X. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00011 · Cited by 499
Self-citationNanozybiotics: advancing antimicrobial strategies through biomimetic mechanisms
Zhou, C., Wang, Q., Cao, H., Jiang, J., & Gao, L. (2024) · Advanced Materials · doi:10.1002/adma.202403362 · Cited by 114
Metadata
- Authors
- Chen, Z., Ji, H., Liu, C., Bing, W., Wang, Z., & Qu, X.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2016-08-03
- Volume
- 55
- Issue
- 36
- Pages
- 10732-10736
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2493956367
- Cited by
- 266
- References
- 56
- FWCI
- 8.44
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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